3-Hydroxyquinuclidinium derivatives: Synthesis of compounds and inhibition of acetylcholinesterase

Chemico-Biological Interactions

Volumn 119-120, Issue , 1999, Pages 173-181

  Reiner, Elsa ^a   Škrinjarić Špoljar, Mira ^a   Dunaj, Sanja ^a   Simeon Rudolf, Vera ^a   Primožič, Ines ^b   Tomić, Sranka ^b  

^a INSTITUTE FOR MEDICAL RESEARCH AND OCCUPATIONAL HEALTH   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Quinuclidinium carbamates; Quinuclidinium imidazolium compounds; Reaction of acetylthiocholine with quinuclidinium oximes; Reversible and progressive acetylcholinesterase inhibition; Synthesis of quinuclidinium derivatives

Indexed keywords

3 (N,N DIMETHYLCARBAMOYLOXY) 1 [3 (2 HYDROXYIMINOMETHYL 3 METHYL 1 IMIDAZOLIO) 2 OXAPROPYL]QUINUCLIDINIUM DICHLORIDE; 3 (N,N DIMETHYLCARBAMOYLOXY) 1 METHYLQUINUCLIDINIUM IODIDE; 3 HYDROXY 1 [3 (2 HYDROXYIMINOMETHYL 3 METHYL 1 IMIDAZOLIO) 2 OXAPROPYL]QUINUCLIDINIUM DICHLORIDE; 3 QUINUCLIDINOL METHIODIDE; ACETYLCHOLINESTERASE; ACETYLTHIOCHOLINE; OXIME; QUINUCLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; DISSOCIATION CONSTANT; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ERYTHROCYTE; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ACETYLCHOLINESTERASE; ACETYLTHIOCHOLINE; CARBAMATES; CHOLINESTERASE INHIBITORS; DRUG STABILITY; ERYTHROCYTES; HUMANS; IMIDAZOLES; KINETICS; OXIMES; QUINUCLIDINES; SOLUTIONS; WATER;

EID: 0344654713     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(99)00026-5     Document Type: Conference Paper

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