Role of redox cycling and activation by DT-diaphorase in the cytotoxicity of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB-1954) and its analogs

Cancer Letters

Volumn 146, Issue 2, 1999, Pages 217-222

  Miŝkiniene, Vanda ^a   Sergediene, Eglë ^a   Nemeikaite, Auŝra ^a   Segura Aguilar, Juan ^b   Ĉenas, Narimantas ^a  

^a VILNIUS UNIVERSITY   (Lithuania)

^b Unit for Biochemical Toxicology   (Sweden)

Author keywords

5 (Aziridin 1 yl) 2,4 dinitrobenzamide (CB 1954); Cytotoxicity; DT diaphorase; Redox cycling

Indexed keywords

4 NITROACETOPHENONE; 4 NITROBENZOIC ACID; 5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; ANTINEOPLASTIC AGENT; AROMATIC NITRO COMPOUND; NIFUROXIME; NITROBENZENE; NITROFURANTOIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL CELL; ARTICLE; BOVINE LEUKEMIA VIRUS; CATTLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; FIBROBLAST; LIPID PEROXIDATION; NONHUMAN; OXIDATION REDUCTION REACTION; PARTITION COEFFICIENT; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; AZIRIDINES; BIOTRANSFORMATION; NAD(P)H DEHYDROGENASE (QUINONE); OXIDATION-REDUCTION; RATS; SHEEP;

BOVINAE; BOVINE LEUKEMIA VIRUS;

EID: 0344631758     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00271-2     Document Type: Article

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