Desflurane increases heart rate independent of sympathetic activity in dogs

European Journal of Anaesthesiology

Volumn 20, Issue 12, 2003, Pages 945-951

  Picker, O ^a   Schwarte, L A ^a   Schindler, A W ^a   Scheeren, T W L ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Anaesthetics, Inhalation; Parasympathetic Nervous System; Sympathetic Nervous System

Indexed keywords

ATROPINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DESFLURANE; ENFLURANE; FENTANYL; NITROUS OXIDE; ORCIPRENALINE; P 0884; PROPRANOLOL;

ADRENERGIC SYSTEM; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; CHOLINERGIC SYSTEM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEART RATE; HEART RATE VARIABILITY; INHALATION ANESTHESIA; MALE; NONHUMAN; SYMPATHETIC TONE; VAGUS NERVE; WAKEFULNESS;

ADRENERGIC BETA-ANTAGONISTS; ANESTHETICS, INHALATION; ANIMALS; ATROPINE; AUTONOMIC NERVE BLOCK; AWARENESS; BAROREFLEX; DOGS; FEMALE; HEART RATE; HEMODYNAMIC PROCESSES; ISOFLURANE; MALE; PARASYMPATHOLYTICS; PROPRANOLOL; PULMONARY GAS EXCHANGE; SYMPATHETIC NERVOUS SYSTEM; VAGUS NERVE;

EID: 0344629199     PISSN: 02650215     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0265021503001522     Document Type: Article

References (28)

1. Scher AM, Young AC. Reflex control of heart rate in the unanesthetized dog. Am J Physiol 1970; 218: 780-789.
2. Picker O, Scheeren TWL, Arndt JO. Inhalation anaesthetics increase heart rate by decreasing cardiac vagal activity. Br J Anaesth 2001; 87: 748-754.
3. Ebert TJ, Muzi M. Sympathetic hyperactivity during desflurane anesthesia in healthy volunteers. A comparison with isoflurane. Anesthesiology 1993; 79: 444-453.
4. Ebert TJ, Muzi M, Lopatka CW. Neurocirculatory responses to sevoflurane in humans. A comparison to desflurane. Anesthesiology 1995; 83: 88-95.
5. Ebert TJ, Perez F, Uhrich TD, Deshur MA. Desflurane-mediated sympathetic activation occurs in humans despite preventing hypotension and baroreceptor unloading. Anesthesiology 1998; 88: 1227-1232.
6. Pac-Soo CK, Ma D, Wang C, Chakrabarti MK, Whitwam JG. Specific actions of halothane, isoflurane, and desflurane on sympathetic activity and A delta and C somatosympathetic reflexes recorded in renal nerves in dogs. Anesthesiology 1999; 91: 470-478.
7. Gueugniaud PY, Hanouz JL, Vivien B, Lecarpentier Y, Coriat P, Riou B. Effects of desflurane in rat myocardium: comparison with isoflurane and halothane. Anesthesiology 1997; 87: 599-609.
8. Kersten J, Pagel PS, Tessmer JP, Roerig DL, Schmeling WT, Warltier DC. Dexmedetomidine alters the hemodynamic effects of desflurane and isoflurane in chronically instrumented dogs. Anesthesiology 1993; 79: 1022-1032.
9. Boban M, Stowe DF, Buljubasic N, Kampine JP, Bosnjak ZJ. Direct comparative effects of isoflurane and desflurane in isolated guinea pig hearts. Anesthesiology 1992; 76: 775-780.
10. van Leersum E. Eine Methode zur Erleichterung der Blutdruckmessung bei Tieren. Pflügers Arch 1911; 142: 377-395.
11. Picker O, Schindler A, Scheeren TWL. Accuracy and reproducibility of long-term implanted transit-time ultrasound flow probes in dogs. Intensive Care Med 2000; 26: 601-607.
12. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: standards of measurement, physiological interpretation, and clinical use. Circulation 1996; 93: 1043-1065.
13. Ohsumi H, Sakamoto M, Yamazaki T, Okumura F. Effects of fentanyl on carotid sinus baroreflex control of circulation in rabbits. Am J Physiol 1989; 256: R625-R631.
14. Hammel HT, Wyndham CA, Hardy JD. Heat production and heat loss in the dog at 8-36°C environmental temperature. Am J Physiol 1958; 194: 99-108.
15. Doorley BM, Waters SJ, Terrell RC, Robinson JL. MAC of I-653 in beagle dogs and New Zealand white rabbits. Anesthesiology 1988; 69: 89-91.
16. Smith I, White PF, Nathanson M, Gouldson R. Propofol. An update on its clinical use. Anesthesiology 1994; 81: 1005-1043.
17. AHFS Drug Information. Cardiovascular Drugs. Bethesda: American Society of Health-System Pharmacists, 1996: 1202-1209.
18. Takamura M, Parent R, Cernacek P, Lavallee M. Influence of dual ET(A)/ET(B)-receptor blockade on coronary responses to treadmill exercise in dogs. J Appl Physiol 2000; 89: 2041-2048.
19. Stein PK, Kleiger RE. Insights from the study of heart rate variability. Annu Rev Med 1999; 50: 249-261.
20. Berntson GG, Bigger Jr JT, Eckberg DL, et al. Heart rate variability: origins, methods, and interpretive caveats. Psychophysiol 1997; 34: 623-648.
21. Hirsch JA, Bishop B. Respiratory sinus arrhythmia in humans: how breathing pattern modulates heart rate. Am J Physiol 1981; 241: H620-H629.
22. Brown TE, Beightol LA, Koh J, Eckberg DL. Important influence of respiration on human R-R interval power spectra is largely ignored. J Appl Physiol 1993; 75: 2310-2317.
23. Weiskopf RB, Eger EI, Daniel M. Fentanyl, esmolol, and clonidine blunt the transient cardiovascular stimulation induced by desflurane in humans. Anesthesiology 1994; 81: 1350-1355.
24. Vogt A, Thämer V. Vagal and sympathetic reflexes of left ventricular origin on the efferent activity of cardiac and renal nerves on anaesthetized cats. Basic Res Cardiol 1980; 75: 635-645.
25. Skoog P, Mansson J, Thoren P. Changes in renal sympathetic outflow during hypotensive haemorrhage in rats. Acta Physiol Scand 1985; 125: 655-660.
26. Ullman J. Influence of neurohumoral blockade on heart rate and blood pressure responses to haemorrhage in isoflurane anaesthetized rats. Acta Physiol Scand 2000; 169: 189-194.
27. Saeki Y, Hasegawa Y, Shibamoto T, et al. The effects of sevoflurane, enflurane, and isoflurane on baroreceptor - sympathetic reflex in rabbits. Anesth Analg 1996; 82: 342-348.
28. Muzi M, Ebert TJ. A comparison of baroreflex sensitivity during isoflurane and desflurane anesthesia in humans. Anesthesiology 1995; 82: 919-925.