A single point mutation resulting in an adversely reduced expression of DPM2 in the Lec15.1 cells

Biochemical and Biophysical Research Communications

Volumn 312, Issue 3, 2003, Pages 555-561

  Pu, Lixia ^a,b   Scocca, Jane R ^a   Walker, Brian K ^a   Krag, Sharon S ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

DPM synthase; DPM1; DPM2; Expression; Glycosylation; Hamster; Lec15.1 cells; Mutant; Oligosaccharides; Point mutation

Indexed keywords

ALANINE; AMINO ACID; CARRIER PROTEIN; COMPLEMENTARY DNA; DOLICHOL PHOSPHATE MANNOSE; DOLICHOL PHOSPHATE MANNOSE SYNTHASE 1; DOLICHOL PHOSPHATE MANNOSE SYNTHASE 2; DPM2 PROTEIN, HUMAN; GDPMANNOSE DOLICHOLPHOSPHATE MANNOSYLTRANSFERASE; GLUTAMIC ACID; GLYCINE; MANNOSYLTRANSFERASE; PEPTIDE; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LINE; CHIMERA; CHO CELL; CONTROLLED STUDY; DNA TRANSFECTION; DOWN REGULATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUSION; GENETICS; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHENOTYPE; PHYSIOLOGY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION; WILD TYPE;

CRICETINAE; CRICETULUS GRISEUS; MAMMALIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0344616905     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.10.152     Document Type: Article

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