Influence of nutritional status on the pharmacokinetics of acetylsalicylic acid and its metabolites in children with autoimmune disease

American Journal of Clinical Nutrition

Volumn 69, Issue 2, 1999, Pages 318-324

  Lares Asseff, Ismael ^a   Flores Pérez, Janett ^b   Juárez Olguín, Hugo ^b   Ramírez Lacayo, Martha ^b   Loredo Abdalá, Arturo ^b   Carbajal Rodríguez, Luis ^b  

^a INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^b NONE

Author keywords

Acetylsalicylic acid; Acute rheumatic fever; Children; Gentisic acid; Juvenile rheumatoid arthritis; Nutritional status; Pharmacokinetics; Salicylic acid; Salicylic acid metabolism; Salicyluric acid

Indexed keywords

ACETYLSALICYLIC ACID; DRUG METABOLITE; GENTISIC ACID; SALICYLIC ACID; SALICYLURIC ACID;

ADOLESCENT; AREA UNDER THE CURVE; ARTICLE; AUTOIMMUNE DISEASE; BODY HEIGHT; BODY WEIGHT; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG URINE LEVEL; FEMALE; HUMAN; MALE; MALNUTRITION; NUTRITIONAL STATUS; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS;

EID: 0344609736     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/69.2.318     Document Type: Article

References (28)

1. Gortmaker S. Chronic childhood disorders: prevalence and impact. Pediatr Clin North Am 1984;31:3-18.
2. Ansell BM. Rheumatic disorders in childhood. Clin Rheum Dis 1976;2:303-491.
3. Chauffard A, Raymond F. Adenopathies in chronic infectious rheumatism. Rev Med 1987;16:345-54.
4. Macioli EA, Blackburn GL. Nutrition and rheumatic diseases. In: Kelly WN, Harris ED, Rudy S, et al, eds. Texbook of rheumatology. Philadelphia: WB Saunders, 1985:484-97.
5. Johnansson V, Portinsson S, Akesson A, et al. Nutritional status in girls with juvenile chronic arthritis. Hum Nutr Clin Nutr 1986; 40:57-67.
6. Lovell DJ, Henderson CK. Juvenile rheumatoid arthritis. In: Ekvall S, ed. Pediatric nutrition in chronic diseases and developmental disorders. New York: Oxford University Press, 1993:263-8.
7. Henderson CJ, Lovell DJ. Assessment of protein-energy malnutrition in children and adolescents with juvenile rheumatoid arthritis. Arthritis Care Res 1989;2:108-13.
8. Henderson CJ, Lovell DJ, Gregg DJ. A nutritional screening test for use in children and adolescents with juvenile rheumatoid arthritis. J Rheumatol 1992;19:1276-81.
9. Gunsberg H, Bochner F, Graham G. Disposition of and clinical response to salicylates in patients with rheumatoid disease. Clin Pharmacol Ther 1984;35:585-93.
10. Hodges RE, Adelman RD. Nutritional evaluation of the patient. In: Hodges RE, ed. Nutrition in medical practice. Philadelphia: WB Saunders, 1980:13-51.
11. Frisancho AR. Anthropometric standards for the assessment of growth and nutrition status. Ann Arbor, MI: The University of Michigan Press, 1989.
12. Rámos-Galván R. Somatometría pediátrica. Estudio semilongitudinal en niños de la ciudad de México. (Pediatric somatometry. Semilongitudinal study in children of Mexico City.) Arch Invest Med (Mex) 1975:6(suppl):100-251 (in Spanish).
13. Waterlow JC. Classification and definition of protein-calorie malnutrition. Br Med J 1972;3:566-9.
14. Gómez F. Desnutrición. (Desnutrition.) Bol Med Hosp Infant Mex 1946;3:543-51 (in Spanish).
15. Buskin JN, Upton RA, Williams RL. Improved liquid-chromatography of aspirin, salicylate and salicyluric acid in plasma with a modification for determining aspirin metabolites in urine. Clin Chem 1982;28:1200-3.
16. Juárez OH, Flores PJ, Lares AI, Gómez ZA. Determinación de ácido acetil salicílico y sus metabolitos (ácido gentísico, ácido salicilúrico y ácido salicílico) en plasma y en orina. [Determination of acetylsalicylic acid and its metabolites (gentisic acid, salicyluric acid, and salicylic acid) in plasma and urine.] Rev Mex Cien Farm 1994;25:13-8 (in Spanish).
17. Gibaldi M, Perrier D. Pharmacokinetics. 2nd ed. New York: Marcel Dekker, 1982.
18. Levy G. Applied pharmacokinetics. In: Evans WE, Schentag JJ, Jusko WJ, eds. Applied pharmacokinetics. 2nd ed. Spokane, WA: Applied Therapeutics, 1986:21-4.
19. Solomons NW. Micronutrient deficiencies in inflammatory bowel disease. Clin Nutr 1983;4(suppl):19-25.
20. Frenk S. Protein-energy malnutrition. In: Arneil GC, Metcoff J, eds. Pediatric nutrition. London: Butterworth, 1985:151-93.
21. Bravo ME, Jarpa S, Monckeberg F, Pizarro G. Cinética de niveles plasmáticos de salicilato en niños desnutridos. (Plasma level kinetics of salicylates in malnourished children.) Rev Chil Pediatr 1978; 49:45-50 (in Spanish).
22. Shastri RA. Steady-state kinetics of salicylic acid in undernutrition. World Rev Nutr Diet 1984;43:192-7.
23. Treluyer JM, Sultan E, Alexandre JA, et al. Pharmacocinetique de l'aspirine chez l'enfant Africain normonutri et malnutri. (Pharmacokinetics of aspirin in African children with normal nutrition and malnutrition.) Arch Fr Pediatr 1991;48:337-41 (in French).
24. Ashton M, Bolme P, Zerihun G. Protein binding of salicylic and salicyluric acid in serum from malnourished children: the influence of albumin, competitive binding and non-esterified fatty acids. J Pharm Pharmacol 1989;41:474-80.
25. Ashton M, Bolme P, Zerihum G, Holmberg K, Paalzow LK. Disposition of salicylic acid in malnourished Ethiopian children after single oral dose. Clin Pharmacokinet 1993;25(suppl):483-94.
26. Levy G, Tsuchiya T, Ansel LP. Limited capacity for salicyl phenolic glucuronide formation and its effect on the kinetics of salicylate elimination in man. Clin Pharmacol Ther 1972;13:258-68.
27. Levy G, Tsuchiya T. Salicylate accumulation kinetics in man. N Engl J Med 1972;287:430-2.
28. Lares-Asseff L, Cravioto J, Santiago P, Ortiz B. Kinetics of metronidazole in severely malnourished and nutritionally rehabilitated children. Clin Pharmacol Ther 1992;51:142-50.