The mucilage of yam (Dioscorea batatas Decne) tuber exhibited angiotensin converting enzyme inhibitory activities

Botanical Bulletin of Academia Sinica

Volumn 44, Issue 4, 2003, Pages 267-273

  Lee, Mei Hsien ^a   Lin, Yin Shiou ^a   Lin, Yaw Huei ^b   Hsu, Feng Lin ^a   Hou, Wen Chi ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b INSTITUTE OF PLANT AND MICROBIAL BIOLOGY   (Taiwan)

Author keywords

Angiotensin converting enzyme (ACE); HPLC; Mucilage; N (3 2 furyl acryloyl Phe Gly Gly) (FAPGG); TLC; Yam

Indexed keywords

DIOSCOREA; DIOSCOREA ALATA; DIOSCOREA BATATAS;

EID: 0344584948     PISSN: 00068063     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Akoruda, M.O. 1984. Genetic improvement of vegetable crops: yam (Dioscorea spp.). In M. Kasloo (ed.), Genetic Improvement of Vegetable Crops. Pergamon Press, pp. 717-733.
2. Anzenbacherova, E., P. Anzenbacher, K. Macek, and J. Kvetina. 2001. Determination of enzyme (angiotensin convertase) inhibitors based on enzymatic reaction followed by HPLC. J. Phrmaceut. Biomed. Analys. 24: 1151-1156.
3. Carney, S.L. 1986. Proteoglycans, chapter 4. Carbohydrate analysis. In M. F. Chaplin and J.F. Kennedy (eds.), A Practical Approach. IRL Press Limited, pp. 97-141.
4. Chen, T.L., K.S. Ken, and H.M. Chang. 1999. Study on the preparation of angiotension-converting enzyme inhibitors (ACEI) from hydrolysates of gelatin. J. Chin. Agric. Chem. Soc. 37: 546-553.
5. Chen, T.L., Y.C. Lo, W.T. Hu, M.C. Wu, S.T. Chen, and H.M. Chang. 2003. Microencapsulation and modification of synthetic peptides of food proteins reduces the blood pressure of spontaneously hypertensive rats. J. Agric. Food Chem. 51: 1671-1675.
6. Dunbabin, D. 1992. Cost-effective intervention in stroke. Pharmacoeconomics 2: 468-499.
7. Fotherby, M.D. and B. Panayiotou. 1999. Antihypertensive therapy in the prevention of stroke: what, when, and for whom? Drugs 58: 663-674.
8. Holmquist, B., P. Bunning, and J.F. Riordan. 1979. A continuous spectrophotometric assay for angiotensin converting enzyme. Anal. Biochem. 95: 540-548.
9. Hou, W.C., J.S. Liu, H.J. Chen, T.E. Chen, C.F. Chang, and Y. H. Lin. 1999a. Dioscorin, the major tuber storage protein of yam (Dioscorea batatas Decne), with carbonic anhydrase and trypsin inhibitor activities. J. Agric. Food Chem. 47: 2168-2172.
10. Hou, W.C., H.J. Chen, and Y.H. Lin. 1999b. Dioscorin, the major tuber storage protein of yam (Dioscorea batatas Decne), with dehydroascorbate reductase and monodehydroascorbate reductase activities. Plant Sci. 149: 151-156.
11. Hou, W.C., M.H. Lee, H.J. Chen, W.L. Liang, C.H. Han, Y.W. Liu, and Y.H. Lin. 2001. Antioxidant activities of dioscorin, the tuber storage protein of yam (Dioscorea batatas Decne). J. Agric. Food Chem. 49: 4956-4960.
12. Hou, W.C., F.L. Hsu, and M.H. Lee. 2002. Yam (Dioscorea batatas) tuber mucilage exhibited antioxidant activities in vitro. Planta Medica 68: 1072-1076.
13. Hou, W.C., H.J. Chen, and Y.H. Lin. 2003. Antioxidant peptides with angiotensin converting enzyme inhibitory activities and applications for angiotensin converting enzyme purification. J. Agric. Food Chem. 51: 1706-1709.
14. Kim, S.K., H.G. Byun, P.J. Park, and F. Shahidi. 2001. Angiotension I converting enzyme inhibitory peptides purified from bovine skin gelatin hydrolysate. J. Agric. Food Chem. 49: 2992-2997.
15. Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
16. Mark, K.S. and T.P. Davis. 2000. Stroke: development, prevention and treatment with peptidase inhibitors. Peptides 21: 1965-1973.
17. sl-casein. Agric. Biol. Chem. 51: 2557-2561.
18. Misaki, A., T. Ito, and T. Harada. 1972. Constitutional studies on the mucilage of yamanoimo, Dioscorea batatas Decne, forma Tsukune. Isolation and structure of a mannan. Agri. Biol. Chem. 36: 761-771.
19. Mullally, M.M., H. Meisel, and R. J. FitzGerald. 1996. Synthetic peptides corresponding to α-lactalbumin and β-lactoglobulin sequences with angiotension-I-converting enzyme inhibitory activity. Biol. Chem. 377: 259-260.
20. Neuhoff, V., R. Stamm, and H. Eibl. 1985. Clear background and highly sensitive protein staining with Coomassie blue dyes in polyacrylamide gels: a systematic analysis. Electrophoresis 6: 427-448.
21. Pihlanto-Leppälä, A., T. Rokka, and H. Korhonen. 1998. Angiotensin I converting enzyme inhibitory peptides derived from bovine milk proteins. Int. Dairy J. 8: 325-331.
22. Tsai, S.S. and F.J. Tai. 1984. Studies on the mucilage from tuber of yam (Dioscorea alata Linn.) I. Isolation and purification of the mucilage. J. Chin. Agri. Chem. Soc. 22: 88-94.
23. Yano, S., K. Suzuki, and G. Funatsu. 1996. Isolation from azein of thermolysin peptides with angiotension I-converting enzyme inhibitory activity. Biosci. Biotechnol. Biochem. 60:661-663.