A mutant streptokinase lacking the C-terminal 42 amino acids is less immunogenic

Immunology Letters

Volumn 70, Issue 3, 2000, Pages 213-218

  Torrèns, Isis ^a   Ojalvo, Ariana G ^a   Seralena, Alina ^a   Hayes, Orlando ^b   De La Fuente, Josè ^b  

^a Center of Pharmaceutical Chemistry Cuba   (Cuba)

^b Mammalian Cell Genetics Division   (Cuba)

Author keywords

Antibodies; Immunology; Neutralizing antibodies; Streptokinase

Indexed keywords

MUTANT PROTEIN; STREPTOKINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DELETION MUTANT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMORAL IMMUNITY; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; CERCOPITHECUS AETHIOPS; FEMALE; FIBRINOLYTIC AGENTS; MALE; MUTATION; NEUTRALIZATION TESTS; PEPTIDE FRAGMENTS; PROTEIN ENGINEERING; SEQUENCE DELETION; STREPTOKINASE; THROMBOSIS;

EID: 0344577977     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2478(99)00151-0     Document Type: Article

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