Human δ-opioid receptor gene and susceptibility to heroin and alcohol dependence

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 88, Issue 5, 1999, Pages 462-464

  Franke, Petra ^a   Nöthen, Markus M ^a   Wang, Tao ^a   Neidt, Helge ^a   Knapp, Michael ^a   Lichtermann, Dirk ^a   Weiffenbach, Olaf ^a   Mayer, Peter ^b   Höllt, Volker ^b   Propping, Peter ^a   Maier, Wolfgang ^a  

^a UNIVERSITY OF BONN   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Opioid receptor gene; Addiction; Alcoholism; Candidate gene; Case control study; Family based association study; Heroin dependence

Indexed keywords

DELTA OPIATE RECEPTOR;

ADULT; ALCOHOLISM; ARTICLE; FAMILY HISTORY; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HEROIN DEPENDENCE; HUMAN; MAJOR CLINICAL STUDY; NUCLEIC ACID BASE SUBSTITUTION; POINT MUTATION; PRIORITY JOURNAL; RISK ASSESSMENT;

ADULT; ALCOHOLISM; ALLELES; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEROIN DEPENDENCE; HUMANS; MALE; MIDDLE AGED; PARENTS; POLYMORPHISM, GENETIC; RECEPTORS, OPIOID, DELTA;

EID: 0344563598     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19991015)88:5<462::AID-AJMG4>3.0.CO;2-S     Document Type: Article

References (6)

1. Befort K, Mattel MG, Roeckel N, et al. 1994. Chromosomal localization of the delta opioid receptor gene to human 1p34.3-p36.1 and mouse 4D bands by in situ hybridization. Genomics 20:143-145.
2. Kieffer BL, Befort K, Gaveriaux-Ruff C, et al. 1992. The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc Natl Acad Sci USA 89:12048-12052.
3. Mayer P, Rochlitz H, Rauch E, et al. 1997. Association between delta-opioid receptor gene polymorphism and heroin dependence in man. NeuroReport 8:2547-2550.
4. Merikangas KR, Rounsaville BJ, Prusoff BA. 1992. Familial factors in vulnerability to substance abuse. In: Meyer Glantz D, Pickens R, editors. Vulnerability to Drug Abuse. Washington, DC: American Psychological Association, p 75-97.
5. Spielman RS, McGinnis RE, Ewens WJ. 1993. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52:506-516.
6. Uhl GR, Childers S, Pasternak G. 1994. An opiate-receptor family reunion. TINS, 17:89-93.