The use of regional coordinating centers in large clinical trials: The DIG trial

Controlled Clinical Trials

Volumn 24, Issue 6 SUPPL., 2003, Pages S298-S305

  Collins, Joseph F ^a,b,h   Martin, Sylvia ^c   Kent, Eleanor ^d   Liuni, Connie ^e   Garg, Rekha ^f,g   Egan, Debra ^g  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c UNIVERSITY OF ALBERTA   (Canada)

^d ST JOSEPH S HOSPITAL   (Canada)

^e SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^f ELI LILLY AND COMPANY   (United States)

^g NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^h VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Digoxin; Heart failure; Large simple trial; Randomized clinical trials; Regional coordinating centers

Indexed keywords

ARTICLE; CANADA; CLINICAL TRIAL; FOLLOW UP; HUMAN; METHODOLOGY; ORGANIZATION; PROBLEM SOLVING; SUPPORT GROUP; TRAINING; UNITED STATES; WORKLOAD;

EID: 0344552401     PISSN: 01972456     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-2456(03)00101-6     Document Type: Article

References (3)

1. Yusuf S., Collins R., Peto R. Why do we need some large simple randomized trials? Stat Med. 3:1984;409-420.
2. Yusuf S., Held P., Teo K., Toretsky E.R. Selection of patients for randomized controlled trials: implications of wide narrow eligibility criteria. Stat Med. 9:1990;73-86.
3. Collins J.F., Garg R., Teo K.K., Williford W.O., Howell C.L. The role of the data coordinating center in the IRB review and approval process: the DIG trial experience. Control Clin Trials. 24:2003;306S-315S.