Defining the tolerable level of ergot in the diet of weaned pigs

Canadian Journal of Animal Science

Volumn 83, Issue 3, 2003, Pages 493-500

  Oresanya, T F ^a,b   Patience, J F ^a   Zijlstra, R T ^a   Beaulieu, A D ^a   Middleton, D M ^b   Blakley, B R ^b   Gillis, D A ^a  

^a PRAIRIE SWINE CENTRE INC   (Canada)

^b Dept of Animal and Poultry Science ^*  (Canada)

Author keywords

Alkaloid; Ergot; Performance; Pig; Prolactin; Toxicity

Indexed keywords

SUS SCROFA; TRITICUM AESTIVUM;

EID: 0344531473     PISSN: 00083984     EISSN: None     Source Type: Journal    
DOI: 10.4141/A03-008     Document Type: Article

References (40)

1. Association of Official Analytical Chemists. 1990. Official methods of analysis. 16th ed. AOAC, Arlington, VA.
2. Ascoli, M. and Segaloff, D. L. 1995. Adenohypophyseal hormones and their hypothalamic releasing factors. Pages 1363-1382 in J. G. Hardman and L. E. Limbird, eds. The pharmacological basis of therapeutics. 9th ed. Pergamon, New York, NY.
3. Bailey, J., Wrathall, A. E. and Mantle, P. G. 1973. The effect of feeding ergot to gilts during early pregnancy. Br. Vet. J. 129: 127-133.
4. Baum, M., Lagudah, E. S. and Appels, R. 1992. Wide crosses in cereals. Annu. Rev. Plant Physiol. Plant Mol. Biol. 43: 117-143.
5. Bennett, J. W. and Bentley, R. 1999. Pride and prejudice: the story of ergot. Perspect. Biol. Med. 42: 333-355.
6. Blaney, B. J., Kopinski, J. S., Magee, M. H., McKenzie, R. A., Blight, J. W., Maryam, R. and Downing, J. A. 2000. Blood prolactin depression in growing pigs fed sorghum ergot (Claviceps Africana). Aust. J. Agric. Res. 51: 785-791.
7. Burfening, P. J. 1994. Ergotism in domestic livestock. Pages 8.1-8.11 in Montana Nutrition Conference Special Report SR-50. Montana State University, Bozeman, MT.
8. Canadian Council on Animal Care. 1993. Guide to the care and use of experimental animals. Volume 1. 2nd ed. E. D. Olfert, B. M. Cross, and A. A. McWilliam, eds. CCAC, Ottawa, ON.
9. Canadian Grain Commission. 2002. The CGS and ergot. [Online] Available: http://www.grainscanada.gc.ca/pubs/factsfarm/factsfarmers10.htm [18 March 2002].
10. Downing, J. A., Joss, J. and Scaramuzzi, R. J. 1995. Ovulation rate and the concentrations of gonadotrophins and metabolic hormones in ewes infused with glucose during the late luteal phase of the oestrous cycle. J. Endocrinol. 146: 403-410.
11. Dunnett, C. W. 1964. New tables for multiple comparisons with a control. Biometrics 20: 482-491.
12. Evans, K. R. and Eikelboom, R. 1987. Feeding induced by ventricular bromocriptine and amphetamine: a possible excitatory role for dopamine in eating behavior. Behav. Neurosci. 101: 591-593.
13. Farmer, C. 2001. The role of prolactin for mammogenesis and galactopoiesis in swine. Livest. Prod. Sci. 70: 105-113.
14. Fawcett, J. K. and Scott, J. E. 1960. A rapid precise method for the determination of urea. J. Clin. Pathol. 13: 156-159.
15. Fluckiger, E., Doepfner, W., Marko, M. and Niederer, W. 1976. Effects of ergot alkaloids on the hypothalamic pituitary axis. Postgrad. Med. J. 52 (Suppl. 1): 57-63.
16. Halford, J. C. and Blundell, J. E. 2000. Pharmacology of appetite suppression. Prog. Drug Res. 54: 25-58.
17. Janssen, G. B., Beems, R. B., Speijers, G. J. and van Egmond, H. P. 2000a. Subacute toxicity of alpha-ergocryptine in Sprague-Dawley rats. 1. General toxicological effects. Food Chem. Toxicol. 38: 679-688.
18. Janssen, G. B., Beems, R. B., Elvers, L. H. and Speijers, G. J. 2000b. Subacute toxicity of alpha-ergocryptine in Sprague-Dawley rats. 2. Metabolic and hormonal changes. Food Chem. Toxicol. 38: 689-695.
19. Kren, V. 1999. Biotransformations of ergot alkaloids. Pages 229-226 in V. Kren and L. Cvak, eds. Ergot: the genus Claviceps. Harwood Academic Publishers, Amsterdam, The Netherlands.
20. Lipham, L. B., Porter, J. K., Norred, W. P., Booth, N. H. and Robbins, J. D. 1987. Quipazine-metoclopramide inhibition of CB-154-induced prolactin suppression in rats: neurotransmitter-metabolite correlations. Proc. Soc. Exp. Biol. Med. 184: 250-255.
21. Lorenz, K. 1979. Ergot on cereal grains. Crit. Rev. Food Sci. Nutr. 11: 311-354.
22. McCarthy, J. F., Aherne, F. X. and Okai, D. B. 1974. Use of HCl insoluble ash as an index material for determining apparent digestibility with pigs. Can. J. Anim. Sci. 54: 107-109.
23. Manev, H., Pericic, D. and Muck-seler, D. 1989. Inhibitory influence of dihydroergosine in the aggressiveness of rats and mice. Pharmacol. Biochem. Behav. 32: 111-115.
24. Melmed S. 1990. Acromegaly. N. Engl. J. Med. 322: 966-977.
25. Nickerson, M. 1970. Drugs inhibiting adrenergic nerves and structures innervated by them. Pages 549-584 in L. S. Goodman and A. Gillman, eds. The pharmacological basis of therapeutics. 4th ed. Macmillan, New York, NY.
26. National Research Council. 1998. Nutrient requirement of swine. 10th ed. National Academy Press, Washington, DC.
27. Opara, E. I., Meguid, M. M., Yang, Z. J. and Hammond, W. G. 1996. Studies on the regulation of food intake using rat total parenteral nutrition as a model. Neurosci. Biobehav. Rev. 20: 413-443.
28. Pearse, P. 1999. Ergot of cereals and grasses. [Online] Available: http//www.cgc.ca/views/ergot/ergot99-e.htm [21 December 1999].
29. Peroutka, S. J. 1995. Drugs effective in the treatment of migraine. Pages 487-502 in J. G. Hardman, and L. E. Limbird eds. The pharmacological basis of therapeutics. 9th ed. Pergamon, New York, NY.
30. Pfeuffer-Friederich, I. and Kilbinger, H. 1985. The effects of LSD in the guinea-pig ileum. Inhibition of acetylcholine release and stimulation of smooth muscle. Naunyn Schmiedeberg's Arch. Pharmacol. 331:311-315.
31. Rotter, R. G., Marquardt, R. R. and Young, J. C. 1985. Effect of ergot from different sources and of fractionated ergot on the performance of growing chicks. Can. J. Anim. Sci. 65: 953-961.
32. Rotter, R. G. and Phillips, G. D. 1991. Effect of dietary ergot on the mean transit time of digesta in the small intestine of sheep. Can. J. Anim. Sci. 71: 767-771.
33. SAS Institute, Inc. 1990. SAS/STAT user's guide, Version 6, 4th ed. Vols. 1 and 2. SAS Institute, Inc., Cary, NC.
34. Sawosz, E. 1996. The effect of ergot (Claviceps purpurea) on the results of pig fattening. Annals of Warsaw Agric. Univ. Animal Sci. 32: 47-54.
35. Sbarbati, A., Zancanaro, C., Barbatelli, G., Cinti, S. and Osculati, F. 1989. Ultrastructure of pituitary folliculo stellate cells of lactating rat during treatment with 2-bromo-alpha-ergocriptine. Tissue Cell. 21: 841-847.
36. Selby, R. A. 1999. Toxicology of ergot alkaloids in agriculture. Pages 469-477 in V. Kren, and L. Cvak, eds. Ergot: the genus Claviceps. Harwood Academic Publishers, Amsterdam, The Netherlands.
37. Terry, P., Gilbert, D. B. and Cooper, S. J. 1995. Dopamine receptor subtype agonists and feeding behavior. Obes. Res. (Suppl. 4): 515S-523S.
38. Whittemore, C. T., Macer, R. C., Miller, J. K. and Mantle, P. G. 1976. Some consequences of the ingestion by young and growing pigs of feed contaminated with ergot. Res. Vet. Sci. 20: 61-69.
39. Whittemore, C. T., Miller, J. K. and Mantle, P. G. 1977. Further studies concerning the toxicity of ingested ergot sclerotia (Claviceps purpurea) to young and growing pigs. Res. Vet. Sci. 22: 146-150.
40. Young, J. C. 1981. Variability in the content and composition of alkaloids found in Canadian ergot. II. Wheat. J. Environ. Sci. Health, Part B Pestic. Food Contam. Agric. Wastes 16: 381-393.