Application of solvent engineering to optimize lipase-catalyzed 1,3-diglyacylcerols by mixture response surface methodology

Biotechnology Letters

Volumn 25, Issue 21, 2003, Pages 1857-1861

  Liao, Hui Fen ^a   Tsai, Wei Chuan ^b   Chang, Shu Wei ^c   Shieh, Chwen Jen ^b  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

^b DA YEH UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN OCEAN UNIVERSITY   (Taiwan)

Author keywords

1,3 diacylglycerol; Lipase; Mixture response surface methodology; Solvent engineering

Indexed keywords

DIACYLGLYCEROL; HEXANE; N-HEXANE; SOLVENT; TRIACYLGLYCEROL LIPASE; TRIOLEIN;

ARTICLE; CATALYSIS; CHEMICAL ENGINEERING; CHEMICAL MODEL; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPUTER SIMULATION; HYDROPHOBICITY; METHODOLOGY; QUALITY CONTROL; SYNTHESIS;

CATALYSIS; CHEMICAL ENGINEERING; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER SIMULATION; DIGLYCERIDES; HEXANES; HYDROPHOBICITY; LIPASE; MODELS, CHEMICAL; QUALITY CONTROL; SOLVENTS; TRIOLEIN;

EID: 0344531005     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026237829284     Document Type: Article

References (8)

1. Cornell JA (1973) Experiments with mixtures: a review. Technometrics 15: 437-455.
2. Kuo SJ, Parkin KL (1996) Solvent polarity Influences product selectivity of lipase-mediated esterification reactions in microaqueous media. J. Am. Oil Chem. Soc. 73: 1427-1433.
3. Liu KJ, Shaw JF (1995) Synthesis of propylene glycerol monoesters of docosahexaenoic acid and eicosapentaenoic acid by lipase-catalyzed esterification in organic solvents. J. Am. Oil Chem. Soc. 72: 1271-1274.
4. Nagao T, Watanabe H, Goto N, Onizawa K, Taguchi H, Matsuo N, Yasukawa T, Tsushima R, Shimasaki H, Itakura H (2000) Dietary diacylglycerol suppresses accumulation of body fat compared to triacylglycerol in men in a double-blind controlled trial. J. Nutr. 130: 792-797.
5. Ott L (1998) An Introduction to Statistical Methods and Data Analysis. Boston: PWS-Kent Publishing.
6. Rendon X, López-Munguía A, Castillo E (2001) Solvent engineering applied to lipase-catalyzed glycerolysis of triolein. J. Am. Oil Chem. Soc. 78: 1061-1066.
7. Shieh C-J, Akoh CC, Koehler PE (1996) Formulation and optimization of sucrose polyester physical properties by mixture response surface methodology. J. Am. Oil Chem. Soc. 73: 455-460.
8. Statistical Analysis System (1990) SAS User Guide. Cary: SAS Institute Inc.