Regulated EGF receptor binding to F-actin modulates receptor phosphorylation

Biochemical and Biophysical Research Communications

Volumn 312, Issue 4, 2003, Pages 930-936

  Tang, Jun ^a   Gross, David J ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Cell surface receptor; Cytoskeleton; Signal transduction; Tyrosine kinase

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; F ACTIN; PHOSPHATASE; TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHOSPHORYLATION; CARBOXY TERMINAL SEQUENCE; CARCINOMA CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; CYTOSOL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SOLUBILITY; SQUAMOUS CELL CARCINOMA;

EID: 0344495420     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.11.016     Document Type: Article

References (27)

1. Schlessinger J., Ullrich A. Growth factor signaling by receptor tyrosine kinases. Neuron. 9:1992;383-391.
2. Rijken P.J., Hage W.J., van Bergen en Henegouwen P.M., Verkleij A.J., Boonstra J. Epidermal growth factor induces rapid reorganization of the actin microfilament system in human A431 cells. J. Cell Sci. 100:1991;491-499.
3. Gronowski A.M., Bertics P.J. Modulation of epidermal growth factor receptor interaction with the detergent-insoluble cytoskeleton and its effects on receptor tyrosine kinase activity. Endocrinology. 136:1995;2198-2205.
4. van Bergen en Henegouwen P.M., den Hartigh J.C., Romeyn P., Verkleij A.J., Boonstra J. The epidermal growth factor receptor is associated with actin filaments. Exp. Cell Res. 199:1992;90-97.
5. den Hartigh J.C., van Bergen en Henegouwen P.M., Verkleij A.J., Boonstra J. The EGF receptor is an actin-binding protein. J. Cell Biol. 119:1992;349-355.
6. Gronowski A.M., Bertics P.J. Evidence for the potentiation of epidermal growth factor receptor tyrosine kinase activity by association with the detergent-insoluble cellular cytoskeleton: analysis of intact and carboxy-terminally truncated receptors. Endocrinology. 133:1993;2838-2846.
7. Peppelenbosch M.P., Qiu R.-G., de Vries-Smits A.M.M., Tertoolen L.G.J., de Laat S.W., McCormick F., Hall A., Symons M.H., Bos J.L. Rac mediates growth factor-induced arachidonic acid release. Cell. 81:1995;849-856.
8. Peppelenbosch M.P., Tertoolen L.G., Hage W.J., de Laat S.W. Epidermal growth factor-induced actin remodeling is regulated by 5- lipoxygenase and cyclooxygenase products. Cell. 74:1993;565-575.
9. Boonstra J., Rijken P., Humbel B., Cremers F., Verkleij A., van Bergen en Henegouwen P. The epidermal growth factor. Cell Biol. Int. 19:1995;413-430.
10. Wells A., Ware M.F., Allen F.D., Lauffenburger D.A. Shaping up for shipping out: PLCγ signaling of morphological changes in EGF-stimulated fibroblast migration. Cell Motil. Cytoskel. 44:1999;227-233.
11. Akiyama T., Kadowaki T., Nishida E., Kadooka T., Ogawara H., Fukami Y., Sakai H., Takaku F., Kasuga M. Substrate specificities of tyrosine-specific protein kinases toward cytoskeletal proteins in vitro. J. Biol. Chem. 261:1986;14797-14803.
12. Bretscher A. Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor. J. Cell Biol. 108:1989;921-930.
13. Diakonova M., Payrastre B., van Velzen A.G., Hage W.J., van Bergen en Henegouwen P.M., Boonstra J., Cremers F.F., Humbel B.M. Epidermal growth factor induces rapid and transient association of phospholipase C-gamma 1 with EGF-receptor and filamentous actin at membrane ruffles of A431 cells. J. Cell Sci. 108:1995;2499-2509.
14. van der Heyden M.A., Oude Weernink P.A., van Oirschot B.A., van Bergen en Henegouwen P.M., Boonstra J., Rijken G. Epidermal growth factor-induced activation and translocation of c-Src to the cytoskeleton depends on the actin binding domain of the EGF-receptor. Biochim. Biophys. Acta. 1359:1997;211-221.
15. Roy L.M., Gittinger C.K., Landreth G.E. Epidermal growth factor treatment of A431 cells alters the binding capacity and electrophoretic mobility of the cytoskeletally associated epidermal growth factor receptor. J. Cell Physiol. 146:1991;63-72.
16. Wiegant F.A., Blok F.J., Defize L.H., Linnemans W.A., Verkley A.J., Boonstra J. Epidermal growth factor receptors associated to cytoskeletal elements of epidermoid carcinoma (A431) cells. J. Cell Biol. 103:1986;87-94.
17. Rotin D., Margolis B., Mohammadi M., Daly R.J., Daum G., Li N., Fischer E.H., Burgess W.H., Ullrich A., Schlessinger J. SH2 domains prevent tyrosine dephosphorylation of the EGF receptor: identification of Tyr992 as the high-affinity binding site for SH2 domains of phospholipase C gamma. EMBO J. 11:1992;559-567.
18. Batzer A.G., Rotin D., Urena J.M., Skolnik E.Y., Schlessinger J. Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor. Mol. Cell. Biol. 14:1994;5192-5201.
19. Holbrook M.R., Slakey L.L., Gross D.J. Thermodynamic mixing of molecular states of the epidermal growth factor receptor modulates macroscopic ligand binding affinity. Biochem. J. 352:2000;99-108.
20. Holbrook M.R., O'Donnell J.B., Slakey L.L., Gross D.J. Epidermal growth factor receptor internalization rate is regulated by negative charges near the SH2 binding site Tyr992. Biochemistry. 38:1999;9348-9356.
21. Waterfield M.D., Mayes E.L., Stroobant P., Bennet P.L., Young S., Goodfellow P.N., Banting G.S., Ozanne B. A monoclonal antibody to the human epidermal growth factor receptor. J. Cell Biochem. 20:1982;149-161.
22. Pardee J.D., Spudich J.A. Purification of muscle actin. Methods Enzymol. 85:1982;164-181.
23. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
24. Gullick W.J., Marsden J.J., Whittle N., Ward B., Bobrow L., Waterfield M.D. Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas. Cancer Res. 46:1986;285-292.
25. Chinkers M., Brugge J.S. Characterization of structural domains of the human epidermal growth factor receptor obtained by partial proteolysis. J. Biol. Chem. 259:1984;11534-11542.
26. Basu M., Biswas R., Das M. 42,000-molecular weight EGF receptor has protein kinase activity. Nature. 311:1984;477-480.
27. Lynch D.K., Winata S.C., Lyons R.J., Hughes W.E., Lehrbach G.M., Wasinger V., Corthals G., Cordwell S., Daly R.J. A cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton. J. Biol. Chem. 278:2003;21805-21813.