Lucigenin and coelenterazine as superoxide probes in mitochondrial and bacterial membranes

Analytical Biochemistry

Volumn 324, Issue 1, 2004, Pages 45-51

  Kervinen, Marko ^a   Pätsi, Jukka ^a   Finel, Moshe ^b   Hassinen, Ilmo E ^a  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Coelenterazine; Lucigenin; Luminescence; NADH:ubiquinone oxidoreductase; Superoxide

Indexed keywords

CELL MEMBRANES; CELL PROLIFERATION; CHEMILUMINESCENCE; LUMINESCENCE; MITOCHONDRIA;

COELENTERAZINE; LUCIGENIN; NICOTINAMIDE ADENINE DINUCLEOTIDES; ONE-ELECTRON REDUCTIONS; OXIDOREDUCTASES; PARACOCCUS DENITRIFICANS; SUBMITOCHONDRIAL PARTICLES; SUPEROXIDES;

PROBES;

COELENTERAZINE; HYPOXANTHINE; LUCIGENIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE; UNCLASSIFIED DRUG; XANTHINE OXIDASE;

ARTICLE; BACTERIAL MEMBRANE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CHEMOLUMINESCENCE; COMPARATIVE STUDY; LIVER MITOCHONDRION; MOLECULAR PROBE; NONHUMAN; PARACOCCUS DENITRIFICANS; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REDUCTION;

BACTERIA (MICROORGANISMS); PARACOCCUS DENITRIFICANS;

EID: 0344494025     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2003.09.004     Document Type: Article

References (30)

1. 0-ATP synthase from Escherichia coli. A model for human mitochondrial disease J. Biol. Chem. 268:1993;12250-12252.
2. 0 ATP synthase Int. J. Biochem. Cell Biol. 31:1999;769-776.
3. Kurki S., Zickermann V., Kervinen M., Hassinen I., Finel M. Mutagenesis of three conserved Glu residues in a bacterial homologue of the ND1 subunit of complex I affects ubiquinone reduction kinetics but not inhibition by dicyclohexylcarbodiimide. Biochemistry. 39:2000;13496-13502.
4. Mather M.W., Rottenberg H. Intrinsic uncoupling of cytochrome c oxidase may cause the maternally inherited mitochondrial diseases MELAS and LHON. FEBS Lett. 433:1998;93-97.
5. Zickermann V., Barquera B., Wikström M., Finel M. Analysis of the pathogenic human mitochondrial mutation ND1/3460, and mutations of strictly conserved residues in its vicinity, using the bacterium Paracoccus denitrificans. Biochemistry. 37:1998;11792-11796.
6. Liochev S.I., Fridovich I. Lucigenin (bis-N-methylacridinium) as a mediator of superoxide anion production. Arch. Biochem. Biophys. 337:1997;115-120.
7. 2·, Free Radicals Biol. Med. 15:1993;447-451.
8. Li Y., Stansbury K.H., Zhu H., Trush M.A. Biochemical characterization of lucigenin (Bis-N-methylacridinium) as a chemiluminescent probe for detecting intramitochondrial superoxide anion radical production. Biochem. Biophys. Res. Commun. 262:1999;80-87.
9. - production. Arch. Biochem. Biophys. 373:2000;447-450.
10. Rembish S.J., Trush M.A. Further evidence that lucigenin-derived chemiluminescence monitors mitochondrial superoxide generation in rat alveolar macrophages. Free Radicals Biol. Med. 17:1994;117-126.
11. Afanas'ev I.B., Ostrachovitch E.A., Korkina L.G. Lucigenin is a mediator of cytochrome c reduction but not of superoxide production. Arch. Biochem. Biophys. 366:1999;267-274.
12. Rees J.F., de Wergifosse B., Noiset O., Dubuisson M., Janssens B., Thompson E.M. The origins of marine bioluminescence: turning oxygen defence mechanisms into deep-sea communication tools. J. Exp. Biol. 201:1998;1211-1221.
13. Teranishi K., Shimomura O. Coelenterazine analogs as chemiluminescent probe for superoxide anion. Anal. Biochem. 249:1997;37-43.
14. De Gier J.W., Lubben M., Reijnders W.N., Tipker C.A., Slotboom D.J., Van Spanning R.J., Stouthamer A.H., van der Oost J. The terminal oxidases of Paracoccus denitrificans. Mol. Microbiol. 13:1994;183-196.
15. +-translocating NADH:ubiquinone oxidoreductase of Paracoccus denitrificans is facilitated by insertion of the ndh gene from Escherichia coli. FEBS Lett. 393:1996;81-85.
16. Schneider W.C. Intracellular distribution of enzymes III. The oxidation of octanoic acid by rat liver fractions. J. Biol. Chem. 176:1948;259-266.
17. Kielley W., Bronk J.R. Oxidative phosphorylation in mitochondrial fragments obtained by sonic vibration. J. Biol. Chem. 230:1958;521-533.
18. Swartz H.M., Sentjurc M., Morse P.D. Cellular metabolism of water-soluble nitroxides: effect on rate of reduction of cell/nitroxide ratio, oxygen concentrations and permeability of nitroxides. Biochim. Biophys. Acta. 888:1986;82-90.
19. Bales B.L., Leon V. Magnetic resonance studies of eukaryotic cells. III. Spin labeled fatty acids in the plasma membrane. Biochim. Biophys. Acta. 509:1978;90-99.
20. Shimomura O. Membrane permeability of coelenterazine analogues measured with fish eggs. Biochem. J. 326:1997;297-298.
21. Tarpey M.M., White C.R., Suarez E., Richardson G., Radi R., Freeman B.A. Chemiluminescent detection of oxidants in vascular tissue. Lucigenin but not coelenterazine enhances superoxide formation. Circ. Res. 84:1999;1203-1211.
22. Janiszewski M., Souza H.P., Liu X., Pedro M.A., Zweier J.L., Laurindo F.R. Overestimation of NADH-driven vascular oxidase activity due to lucigenin artifacts. Free Radicals Biol. Med. 32:2002;446-453.
23. Rapisarda V.A., Montelongo L.R., Farias R.N., Massa E.M. Characterization of an NADH-linked cupric reductase activity from the Escherichia coli respiratory chain. Arch. Biochem. Biophys. 370:1999;143-150.
24. Messner K.R., Imlay J.A. The identification of primary sites of superoxide and hydrogen peroxide formation in the aerobic respiratory chain and sulfite reductase complex of Escherichia coli. J. Biol. Chem. 274:1999;10119-10128.
25. Clark W.M. Oxidation-reduction potentials of organic systems. 1960;Williams & Wilkins, Baltimore. pp. 506-508.
26. Wood P.M. The potential diagram for oxygen at pH 7. Biochem. J. 253:1988;287-289.
27. 2·) radicals. Biochim. Biophys. Acta. 778:1984;579-585.
28. Han D., Williams E., Cadenas E. Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space. Biochem. J. 353:2001;411-416.
29. Henry M.F., Vignais P.M. Production of superoxide anions in Paracoccus denitrificans. Arch. Biochem. Biophys. 203:1980;365-371.
30. Turrens J.F., Alexandre A., Lehninger A.L. Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria. Arch. Biochem. Biophys. 237:1985;408-414.