Molecular cloning and characterization of a human brain-specific gene implicated in neuronal differentiation

Molecular Brain Research

Volumn 54, Issue 1, 1998, Pages 113-123

  Fan, Frank S ^a,b   Shen, Hsin Hsin ^b   Tseng, Wen Ping ^b   Chen, Po Min ^a   Tsai, Shih Feng ^b  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN; COMPLEMENTARY DNA; CYCLINE; NUCLEAR PROTEIN; PROTEIN HB20; RETINOIC ACID; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BRAIN NERVE CELL; COLON CARCINOMA; CONTROLLED STUDY; DATA BASE; GENE FUNCTION; GENE ISOLATION; GLIOMA CELL; HUMAN; HUMAN CELL; LYMPHOMA; MOLECULAR CLONING; NERVE CELL DIFFERENTIATION; NORTHERN BLOTTING; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTO ONCOGENE; SEQUENCE HOMOLOGY; STEM CELL; TRINUCLEOTIDE REPEAT; UTERINE CERVIX CARCINOMA;

AMINO ACID SEQUENCE; BASE SEQUENCE; BRAIN CHEMISTRY; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA, COMPLEMENTARY; FETUS; GENE EXPRESSION; HUMANS; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; NUCLEOSOMES; ORGAN SPECIFICITY; POLYMERASE CHAIN REACTION; PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS; TRINUCLEOTIDE REPEATS; TUMOR CELLS, CULTURED;

EID: 0344474557     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(97)00329-X     Document Type: Article

References (51)

1. Adachi Y., Pavlakis G.N., Copeland T.D. Identification and characterization of SET, a nuclear phosphoprotein encoded by the translocation break point in acute undifferentiated leukemia. J. Biol. Chem. 269:1994;2258-2262.
2. Altschul S.F., Boguski M.S., Gish W., Wootton J.C. Issues in searching molecular sequence databases. Nat. Genet. 6:1994;119-129.
3. Aslanidis C., Jansen G., Amemiya C., Shutler G., Mahadevan M., Tsifidia C., Chen C., Alleman J., Wormskamp N.G.M., Vooijs M., Buxton J., Johnson K., Smeets H.J.M., Lennon G.G., Carrano A.V., Korneluk R.G., Wieringa B., de Jong P.J. Cloning of the essential myotonic dystrophy region and mapping of the putative defect. Nature. 355:1992;548-551.
4. Bourouis M., Heitzler P., Messal M.E., Simpson P. Mutant Drosophila embryos in which all cells adopt a neural fate. Nature. 341:1989;442-444.
5. Brendel V., Bucher P., Nourbakhsh I., Blaisdell B.E., Karlin S. Methods and algorithms for statistical analysis of protein sequences. Proc. Natl. Acad. Sci. 89:1992;2002-2006.
6. Brook J.D., McCurrach M.E., Harley H.G., Buckler A.J., Church D., Aburatani H., Hunter K., Stanton V.P., Thirion J.P., Hudson T., Sohn R., Zemelman B., Snell R.G., Rundle S.A., Crow S., Davies J., Shelbourne P., Buxton J., Jones C., Juvonen V., Johnson K., Harper P.S., Shaw D.J., Housman D.E. Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member. Cell. 68:1992;799-808.
7. Chen C., Okayama H. High-efficiency transformation of mammalian cells by plasimd DNA. Mol. Cell. Biol. 7:1987;2745-2752.
8. Chubet R.G., Brizzard B.L. Vectors for expression and secretion of FLAG epitope-tagged proteins in mammalian cells. Biotechniques. 20:1996;136-141.
9. Devereux J.R., Haeberli P., Smithies O. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12:1984;387-395.
10. Dolz R. GCG: production of multiple sequence alignment. Meth. Mol. Biol. 24:1994;83-99.
11. Feinberg A.P., Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:1983;6-13.
12. Fu Y.-H., Pizzuti A., Fenwick R.G. Jr., King J., Rajnarayan S., Dunne P.W., Dubel J., Nasser G.A., Ashizawa T., de Jong P. An unstable triplet repeat in a gene related to myotonic muscular dystrophy. Science. 255:1992;1256-1258.
13. Fujii-Nakata T., Ishimi Y., Okuda A., Kikuchi A. Functional analysis of nucleosome assembly protein, NAP-1. J. Biol. Chem. 267:1992;20980-20986.
14. Gomez-Marquez J., Segade F. Prothymosin α is a nuclear protein. FEBS Lett. 226:1988;217-219.
15. Hayes T.E., Valtz N.L.M., McKay R.D.G. Downregulation of CDC2 upon terminal differentiation of neurons. New Biol. 3:1991;259-269.
16. Henikoff S., Henikoff J.G. Protein family classification based on searching a database of blocks. Genomics. 19:1994;97-107.
17. Heringa J. The evolution and recognition of protein sequence repeats. Comput. Chem. 18:1994;233-243.
18. The Huntington's Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell. 72:1993;971-983.
19. Ishimi Y., Kojima M., Yamada M., Hanaoka F. Binding mode of nucleosome-assembly protein (AP-1) and histones. Eur. J. Biochem. 162:1987;19-24.
20. Kawaguchi Y., Okamoto T., Taniwaki M., Aizawa M., Inoue M., Katayama S., Kawakami H., Nakamura S., Nishimura M., Akiguchi I., Kimura J., Narumiya S., Kakizuka A. CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1. Nat. Genet. 8:1994;221-227.
21. Kellogg D.R., Kikuchi A., Fujii-Nakata T., Turck C.W., Murray A.W. Memebers of the NAP/SET family of proteins interact specifically with B-type cyclins. J. Cell Biol. 130:1995;661-673.
22. Kellogg D.R., Murray A.W. NAP-1 acts with Clb2 to perform mitotic functions and to suppress polar bud growth in budding yeast. J. Cell Biol. 130:1995;675-685.
23. Knight S.J.L., Flannery A.V., Hirst M.C., Campbell L., Christodoulou Z., Phelps S.R., Pointon J., Middleton-Price H.R., Barnicoat A., Pembrey M.E., Holland J., Oostra B.A., Bobrow M., Davies K.E. Trinucleotide repeat amplification and hypermethylation of a CpG island in FRAXE mental retardation. Cell. 74:1993;127-134.
24. La Spada A.R., Wilson E.M., Lubahn D.B., Harding A.E., Fischbeck K.H. Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Science. 352:1991;77-79.
25. Lees J.F., Schnidman P.S., Skuntz S.F., Carden M.J., Lazzarini R.A. The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it. EMBO J. 7:1988;1947-1955.
26. Lee W.C., Xue Z., Melese T. The NSR1 gene encodes a protein that specifically binds nuclear localization sequences and has two RNA recognition motifs. J. Cell Biol. 113:1991;1-12.
27. Lehmann R., Jimenez R., Dietrich V., Campos-Ortega J.A. On the Phenotype and development of mutants of early neurogenesis in Drosophila melanogaster. Wilhelm Roux's Arch. Dev. Biol. 192:1983;62-74.
28. Morin N., Delsert C., Klessig D.F. Nuclear localization of the adenovirus DNA-binding protein: requirement for two signals and complementation during viral infection. Mol. Cell. Biol. 9:1989;4372-4380.
29. Mullen M.-A., Gerstberger S., Ciufo D.M., Mosca J.D., Hayward G.S. Evaluation of colocalization interactions between the IE110, IE175, and IE63 transactivator proteins of herpes simplex virus within subcellular punctate structures. J. Virol. 69:1995;476-491.
30. Nakai K., Kanehisa M. A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics. 14:1992;897-911.
31. Nakamura T., Alder H., Gu Y., Prasad R., Canaani O., Kamada N., Gale R.P., Lange B., Crist W.M., Nowell P.C., Croce C.M., Canaani E. Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. Proc. Natl. Acad. Sci. 90:1993;4631-4635.
32. Norbury C., Nurse P. Animal cell cycles and their control. Annu. Rev. Biochem. 61:1992;441-470.
33. Orr H.T., Chung M.Y., Banfi S., Kwiatkowski T.J. Jr., Servadio A., Beaudet A.L., McCall A.E., Duvick L.A., Ranum L.P., Zoghbi H.Y. Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1. Nat. Genet. 4:1993;221-226.
34. Patterson P.H., Nawa H. Neuronal differentiation factors/cytokines and synaptic plasticity. Cell 72/Neuron. 10:1993;123-137. Supplement.
35. Pearson W.R. Using the FASTA program to search protein and DNA sequence databases. Meth. Mol. Biol. 25:1994;365-389.
36. Persson B., Argos P. Prediction of transmembrane segments in proteins utilizing multiple sequence alignments. J. Mol. Biol. 237:1994;182-192.
37. Pleasure S.J., Lee V.M.Y. NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell. J. Neurosci. Res. 35:1993;585-602.
38. Pleasure S.J., Page C., Lee V.M.Y. Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J. Neurosci. 12:1992;1802-1815.
39. Queen C., Korn L.J. A comprehensive sequence analysis program for the IBM personal computer. Nucleic Acids Res. 12:1984;581-599.
40. Riggins G.J., Lokey L.K., Leiner H.A., Sherman S.L., Wilkinson K.D., Warren S.T. Human genes containing polymorphic trinucleotide repeats. Nat. Genet. 2:1992;186-191.
41. Ross C.A., McInnis M.G., Margolis R.L., Li S.H. Genes with triplet repeats: candidate mediators of neuropsychiatric disorders. Trends Neurosci. 16:1993;254-260.
42. Sanger F., Nicklen S., Coulsen A.R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. 74:1977;5463-5467.
43. Shen A.L.Y., Hu C.P., Hsia R.C., Tsai L.M., Lee L.S., Chang C. Cellular and antigenic properties of cultured normal and fetal brain and glioma cells. J. Neuroimmunol. 8:1985;141-151.
44. H.H. Shen, F.S. Fan, J. Hoheisel, S.F. Tsai, Identification and characterization of a SET/NAP related protein, encoded by the brain specific gene, MB20, in preparation.
45. Simon H.U., Mills G.B., Kozlowski M., Hogg D., Branch D., Ishimi Y., Siminovitch K.A. Molecular characterization of hNRP, a cDNA encoding a human nucleosome-assembly-protein-1-related gene product involved in the induction of cell proliferation. Biochem. J. 297:1994;389-397.
46. Stultz C.M., White J.V., Smith T.F. Structural analysis based on state-space modeling. Protein Sci. 2:1993;305-314.
47. Tixier-Vidal A. Cell division an differentiation of central nervous system neurons. Ann. New York Acad. Sci. 733:1994;56-67.
48. Verkerk A.J.M.H., Pieretti M., Sutcliffe J.S., Fu Y.H., Kuhl D.P.A., Pizzuti A., Reiner O., Richards S., Victoria M.F., Zhang F., Eussen B.E., van Ommen G.J.B., Blonden L.A.J., Riggins G.J., Chastain J.L., Kunst C.B., Galijaard H., Caskey C.T., Nelson D.L., Oostra B.A., Warren S.T. Identification of a gene (FMR 1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell. 65:1991;905-914.
49. Von Lindern M., Baal S., Wiegant J., Raap A., Hagemeijer A., Grosveld G. Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3′ half to different genes: characterization of the set gene. Mol. Cell. Biol. 12:1992;3346-3355.
50. White J.V., Stultz C.M., Smith T.F. Protein classification by stochastic modeling and optimal filtering of amino acid sequences. Math. Biosci. 119:1994;35-75.
51. Yazawa I., Nukina N., Hashida H., Goto J., Yamada M., Kanazawa I. Abnormal gene product identified in hereditary dentatorubral-pallidoluysian atrophy (DRPLA) brain. Nat. Genet. 10:1995;99-103.