Superiority of combined chemo-embolization and portal infusion with 5-fluorouracil over locoregional infusion concepts in Novikoff hepatoma-bearing rats

Journal of Cancer Research and Clinical Oncology

Volumn 129, Issue 11, 2003, Pages 655-661

  Bödeker, Hermann ^a   Kamphorst, Ernst Jan ^b   Wünsch, Peter H ^c   Linnemann, Ulrich ^c   Berger, Martin R ^b  

^a Department of Gastroenterology   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c Municipal Hospital Nurnberg Nord   (Germany)

Author keywords

Chemoembolization; Ethibloc; Liver tumor; Locoregional therapy

Indexed keywords

ETHIBLOC; FLUOROURACIL; PROLAMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; ARTIFICIAL EMBOLISM; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER MODEL; CANCER SIZE; CANCER TRANSPLANTATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG INFUSION; FEMALE; HEPATIC ARTERY; HEPATOMA CELL; INOCULATION; LIVER; MULTIMODALITY CANCER THERAPY; NONHUMAN; NOVIKOFF HEPATOMA; PORTAL VEIN; PRIORITY JOURNAL; RAT; TOXICITY TESTING; TUMOR NECROSIS;

ANIMALS; COMBINED MODALITY THERAPY; DIATRIZOATE; DRUG COMBINATIONS; EMBOLIZATION, THERAPEUTIC; FATTY ACIDS; FEMALE; FLUOROURACIL; HEPATIC ARTERY; LIVER NEOPLASMS, EXPERIMENTAL; PORTAL VEIN; PROPYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; ZEIN;

EID: 0344442768     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-003-0495-x     Document Type: Article

References (32)

1. Ackermann NB (1974) The blood supply of experimental liver metastases. Changes in vascularity with increasing tumor growth. Surgery 75:589-596
2. Aguiar JL, Berger MR, Frank N (1987) Locoregional application of 5-fluorouracil to the liver: alteration of pharmacokinetics and bone marrow toxicity in rats with thioacetamide-induced cirrhosis. Toxicol Lett 36:181-188
3. Amin Z, Bown SG, Lees WR (1993) Local treatment of colorectal liver metastases: a comparison of interstitial laser photocoagulation (ILP) and percutaneous alcohol injection (PAI). Clin Radiol 48:166-171
4. Bartkowski R, Berger MR, Aguiar JLA, Henne TH, Dörsam J, Geelhaar GH, Schlag P, Herfahrt C (1986) Experiments on the efficacy and toxicity of locoregional chemotherapy of liver tumors with 5-fluoro-2′-deoxyuridine (FUDR) and 5-fluorouracil (5-FU) in an animal model. J Cancer Res Clin Oncol 111:42-46
5. Bassermann R (1984) Angiogenese und Vaskularisation in Metastasen. Verh Dtsch Ges Path 67:1-16
6. Berger MR, Henne TH, Aguiar JLA, Bartkowski R, Dörsam J, Geelhaar GH, Schlag P, Herfarth C, Schmähl D (1986) Experiments on the toxicity of locoregional liver chemotherapy with 5-fluoro-2′-deoxyuridine and 5-fluorouracil in an animal model. Rec Res Cancer Res 100:148-156
7. Bismuth H, Fecteau A (1998) Combination therapy in oncology- hepatocellular carcinoma. Chirurg 69:360-365
8. Bloomston M, Binitie O, Fraiji E, Murr M, Zervos E, Goldin S, Kudryk B, Zwiebel B, Black T, Fargher S, Rosemurgy AS (2002) Transcatheter arterial chemoembolization with or without radiofrequency ablation in the management of patients with advanced hepatic malignancy. Am Surg 68:827-831
9. Bolton JS, Fuhrman GM (2000) Survival after resection of multiple bilobar hepatic metastases from colorectal carcinoma. Ann Surg 231:743-751
10. Choti MA, Sitzmann JV, Tiburi MF, Sumetchotimetha W, Rangsin R, Schulick RD, Lillemoe KD, Yeo CJ, Cameron JL (2002) Trends in long-term survival following liver resection for hepatic colorectal metastases. Ann Surg 235:759-766
11. Curley SA (2001) Radiofrequency ablation of malignant liver tumors. Oncologist 6:14-23
12. Figueras J, Valls C, Rafecas A, Fabregat J, Ramos E, Jaurrieta E (2001) Resection rate and effect of postoperative chemotherapy on survival after surgery for colorectal liver metastases. Br J Surg 88:980-985
13. Fiorentini G, Poddie DB, Cantore M, Giovanis P, Guadagni S, De Giorgi U, Cariello A, Dazzi C, Turci D (2001) Locoregional therapy for liver metastases from colorectal cancer: the possibilities of intraarterial chemotherapy, and new hepatic-directed modalities. Hepatogastroenterol 48:305-312
14. Giovannini M (2002) Percutaneous alcohol ablation for liver metastasis. Semin Oncol 29:192-195
15. Harms J, Obst T, Thorban S, Busch R, Fink U, Heidecke CD, Roder JD, Siewert JR (1999) The role of surgery in the treatment of liver metastases for colorectal cancer patients. Hepatogastroenterol 46:2321-2328
16. Jatzko GR, Lisborg PH, Stettner HM, Klimpfinger MH (1995) Hepatic resection for metastases from colorectal carcinoma: a survival analysis. Eur J Cancer 31A:41-46
17. Kamphorst EJ, Bodeker H, Koroma S, Linnemann U, Berger MR (1999) New technique for superselective arterial (chemo-) embolization of the rat liver. Lab Anim Sci 49:216-219
18. Kemeny NE, Ron IG (1999) Liver metastases. Curr Treat Options Gastroenterol 2:49-57
19. Pocard M, Pouillart P, Asselain B, Salmon R (2000) Hepatic resection in metastatic breast cancer: results and prognostic factors. Eur J Surg Oncol 26:155-159
20. Poon RT, Fan ST, O'Suilleabhain CB, Wong J (2002) Aggressive management of patients with extrahepatic and intrahepatic recurrences of hepatocellular carcinoma by combined resection and locoregional therapy. J Am Coll Surg 195:311-318
21. Rozycki-Gerlach W, Berger MR, Friedl P, Yi J, Schmähl D, Schlag P (1988) First experiments with locoregional chemotherapy in the treatment of autochthonous rat hepatoma. Arch Geschwulstforsch 58:369-378
22. Saltz LB, Kemeny NE (1996) Adjuvant chemotherapy of colorectal cancer. Oncologist 1:22-29
23. Scheele J, Altendorf-Hofmann A (1999) Resection of colorectal liver metastases. Langenbecks Arch Surg 384:313-327
24. Schlag P, Dörsam J, Aguiar JLA, Bartkowski R, Berger MR (1988) Hepatic arterial infusion (HAI) chemotherapy proves to be advantageous in the treatment of experimental liver tumors. Eur J Cancer Clin Oncol 24:1013-1018
25. Schultheis KH (1985) Embolization-chemoembolization. Beitr Onkol 21:201-228
26. Schultheis KH, Gebhardt C, Schwemmle K, Richter EI, Schumacher F (1990) Chemoembolization kolorektaler Lebermetastasen. Zent Bl Chir 115:933-947
27. Seiler CA, Redaelli C, Schmied BM, Baer HU, Buchler MW (2000) Liver resection for liver metastases. 1998 Bern Symposium. Swiss Surg 6:164-168
28. Selzner M, Morse MA, Vredenburgh JJ, Meyers WC, Clavien PA (2000) Liver metastases from breast cancer: long-term survival after curative resection. Surgery 127:383-389
29. Skitzki JJ, Chang AE (2002) Hepatic artery chemotherapy for colorectal liver metastases: technical considerations and review of clinical trials. Surg Oncol 11:123-135
30. Vogl TJ, Muller PK, Mack MG, Straub R, Engelmann K, Neuhaus P (1999) Therapeutic options in non-resectable liver metastases. Percutaneous radiological interventions. Chirurg 70:133-140
31. Weimann A, Varnholt H, Schlitt HJ, Lang H, Flemming P, Hustedt C, Tusch G, Raab R (2000) Retrospective analysis of prognostic factors after liver resection and transplantation for cholangiocellular carcinoma. Br J Surg 87:1182-1187
32. Wittmer A, Khazaie K, Berger MR (1999) Quantitative detection of lac-Z-transfected CC531 colon carcinoma cells in an orthotopic rat liver metastasis model. Clin Exp Metastas 17:369-376