Effects of orally administered OP-1206 α-CD with loxoprofen-Na on walking dysfunction in the rat neuropathic intermittent claudication model

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 69, Issue 4, 2003, Pages 269-273

  Nakai, Katsuhiko ^a   Takenobu, Yoshifumi ^a   Takimizu, Hideyuki ^a   Akimaru, Shinji ^a   Ito, Hidenori ^a   Maegawa, Hitoshi ^a   Marsala, Martin ^b   Katsube, Nobuo ^a  

^a ONO PHARMACEUTICAL CO   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Intermittent claudication; Loxoprofen Na; OP 1206 CD; Spinal canal Stenosis; Spinal cord blood flow

Indexed keywords

20 DIMETHYL DELTA 2 PROSTAGLANDIN E1 ALPHA CYCLODEXTRIN CLATHRATE; LIMAPROST; LOXOPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E1 DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; EPIDURAL SPACE; GAIT DISORDER; INTERMITTENT CLAUDICATION; LASER DOPPLER FLOWMETRY; MALE; METHODOLOGY; NEUROPATHY; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD BLOOD FLOW; TREADMILL; TREATMENT OUTCOME; VERTEBRAL CANAL STENOSIS; WALKING;

EID: 0344441869     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-3278(03)00109-1     Document Type: Article

References (20)

1. L.I. Malis, Lumbar stenosis, Mt. Sinai. J. Med. 58 (1991) 121-124.
2. N.C. Spanos, J. Andrew, Intermittent claudication and lateral lumbar disk protrusions, J. Neurol. Neurosurg. Psychiat. 29 (1966) 273-277.
3. J.N. Blau, V. Logue, Intermittent claudication of cauda equina: an unusual syndrome resulting from central protrusion of a lumbar intervertebral disc, Lancet 1 (1961) 1081-1086.
4. K. Takahashi, S. Nomura, K. Tomita, Effects of peripheral nerve stimulation on the blood flow of the spinal cord and the nerve root, Spine 13 (1988) 1278-1283.
5. C.B. Wilson, Significance of the small lumbar spinal canal: cauda equina compression syndromes due to spondylosis. Part 3: intermittent claudication, J. Neurosurg. 31 (1969) 499-506.
6. M. Murakami, K. Takahashi, T. Sekikawa, K. Yasuhara, M. Yamagata, H. Moriya, Effects of intravenous lipo-prostaglandin E1 on neurogenic intermittent claudication, J. Spinal Disord. 10 (1997) 499-504.
7. K. Yone, T. Sakou, Y. Kawauchi, The effect of lipo-prostaglandin E1 on cauda equina blood flow in patients with lumbar spinal canal stenosis: myeloscopic observation, Spinal Cord 37 (1999) 269-274.
8. S.H. Ferreira, J.R. Vane, Prostaglandins: their disappearance from and release into the circulation, Nature 216 (1967) 868-873.
9. B. Fujitani, M. Watanabe, J. Kuwashima, T. Tsuboi, T. Kadokawa, T. Kitagawa, Effect of a prostaglandin E1 derivative (OP-1206) and acetylsalicylic acid on electrically induced thrombosis in guinea-pig mesenteric artery and its modification by an inhibitor of prostaglandin I2 synthetase, tranylcypromine, Jpn. J. Pharmacol. 40 (1986) 31-35.
10. T. Tsuboi, B. Fujitani, J. Maeda, et al., Effect of OP 1206, a prostaglandin E1 derivative, on guinea-pig platelet functions, Thromb. Res. 20 (1980) 573-580.
11. T. Tsuboi, N. Hatano, K. Nakatsuji, et al., Pharmacological evaluation of OP 1206, a prostaglandin E1 derivative, as an anti-anginal agent, Arch. Int. Pharmacodyn. Ther. 247 (1980) 89-102.
12. Y. Takenobu, N. Katsube, M. Marsala, K. Kondo, Model of neuropathic intermittent claudication in the rat: methodology and application, J. Neurosci. Meth. 104 (2001) 191-198.
13. K. Nakai, Y. Takenobu, K. Eguchi, et al., The effects of OP-1206 α-CD on walking dysfunction in the rat neuropathic intermittent claudication model, Anesth. Analg. 94 (2002) 1537-1541.
14. N. Futaki, K. Yoshikawa, Y. Hamasaka, et al., NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions, Gen. Pharmac. 24 (1993) 105-110.
15. E. Misaka, T. Yamaguchi, Y. Iizuka, et al., Anti-inflammatory, analgesic and antipyretic activities of sodium 2-[4-(2-oxocyclopentan-1-ylmethyl)phenyl] propionate dihydrate (CS-600), Pharmacometrics 21 (1981) 753-771.
16. S. Waikakul, W. Waikakul, A post marketing survey on the effects of loxoprofen, J. Med. Asssoc. Thai. 82 (1999) 721-726.
17. J. Orendacova, D. Cizkova, J. Kafka, et al., Cauda equina syndrome, Prog. Neurobiol. 64 (2001) 613-637.
18. S.E. Abram, T.C. O'Connor, Complications associated with epidural steroid injections, Reg. Anesth. 21 (1996) 149-162.
19. M. Fukusaki, I. Kobayashi, T. Hara, K. Sumikawa, Symptoms of spinal stenosis do not improve after epidural steroid injection, Clin. J. Pain 14 (1998) 148-151.
20. T. Yamamoto, N. Shimoyama, H. Asano, T. Mizuguchi, OP-1206, a prostaglandin E1 derivative, attenuates the thermal hyperesthesia induced by constriction injury to the sciatic nerve in the rat, Anesth. Analg. 80 (1995) 515-520.