Molecular imaging and cancer

Molecular Cancer Therapeutics

Volumn 2, Issue 3, 2003, Pages 335-343

  Blasberg, Ronald G ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; DIAGNOSTIC IMAGING; HUMAN; METHODOLOGY; NEOPLASM; REVIEW;

ANIMALS; DIAGNOSTIC IMAGING; HUMANS; NEOPLASMS;

EID: 0344438131     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (43)

1. Wick, R. A. Photon counting imaging: applications in biomedical research. Biotechniques, 7: 262-269, 1989.
2. Hooper, C. E., Ansorge, R. E., Browne, H. M., and Tomkins, P. CCD imaging of luciferase gene expression in single mammalian cells. J. Biolumin. Chemilumin., 5: 123-130, 1990.
3. Welsh, S., and Kay, S. A. Reporter gene expression for monitoring gene transfer. Curr. Opin. Biotechnol., 8: 617-622, 1997.
4. Weissleder, R., Reimer, P., Lee, A. S., Wittenberg, J., and Brady, T. J. MR receptor imaging: ultrasmall iron oxide particles targeted to asialoglycoprotein receptors. Am. J. Roentgenol., 155: 1161-1167, 1990.
5. Weissleder, R., Lee, A. S., Fischman, A. J., Reimer, P., Shen, T., Wilkinson, R., Callahan, R. J., and Brady, T. J. Polyclonal human immunoglobulin G labeled with polymeric iron oxide: antibody MR imaging. Radiology, 181: 245-249, 1991.
6. Kayyem, J. F., Kumar, R. M., Fraser, S. E., and Meade, T. J. Receptor-targeted co-transport of DNA and magnetic resonance contrast agents. Chem. Biol., 2: 615-620, 1995.
7. Weissleder, R., Simonova, M., Bogdanova, A., Bredow, S., Enochs, W. S., and Bogdanov, A. MR imaging and scintigraphy of gene expression through melanin induction. Radiology, 204: 425-429, 1997.
8. Louie, A. Y., Huber, M. M., Ahrens, E. T., Rothbacher, U., Moats, R., Jacobs, R. E., Fraser, S. E., and Meade, T. J. In vivo visualization of gene expression using magnetic resonance imaging. Nat. Biotechnol., 18: 321-325, 2000.
9. Tjuvajev, J. G., Stockhammer, G., Desai, R., Uehara, H., Watanabe, H., Gansbacher, B., and Blasberg, R. G. Imaging the expression of transfected genes in vivo. Cancer Res., 55: 6126-6132, 1995.
10. Tjuvajev, J. G., Finn, R., Watanabe, K., Joshi, R., Oku, T., Kennedy, J., Beattie, B., Koutcher, J., Larson, S., and Blasberg, R. G. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res., 56: 4087-4095, 1996.
11. Tjuvajev, J. G., Avril, N., Oku, T., Sasajima, T., Miyagawa, T., Joshi, R., Safer, M., Beattie, B., DiResta, G., Daghighian, F., Augensen, F., Koutcher, J., Zweit, J., Humm, J., Larson, S. M., Finn, R., and Blasberg, R. Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res., 58: 4333-4341, 1998.
12. Gambhir, S. S., Barrio, J. R., Wu, L., Iyer, M., Namavari, M., Satyamurthy, N., Bauer, E., Parrish, C., MacLaren, D. C., Borghei, A. R., Green, L. A., Sharfstein, S., Berk, A. J., Cherry, S. R., Phelps, M. E., and Herschman, H. R. Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir. J. Nucl. Med., 39: 2003-2011, 1998.
13. Gambhir, S. S., Barrio, J. R., Phelps, M. E., Iyer, M., Namavari, M., Satyamurthy, N., Wu, L., Green, L. A., Bauer, E., MacLaren, D. C., Nguyen, K., Berk, A. J., Cherry, S. R., and Herschman, H. R. Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography. Proc. Natl. Acad. Sci. USA, 96: 2333-2338, 1999.
14. Mayerhofer, R., Araki, K., and Szalay, A. A. Monitoring of spatial expression of firefly luciferase in transformed zebrafish. J. Biolumin. Chemilumin., 10: 271-275, 1995.
15. Bennett, J., Duan, D., Engelhardt, J. F., and Maguire, A. M. Real-time, noninvasive in vivo assessment of adeno-associated virus-mediated retinal transduction. Investig. Ophthalmol. Vis. Sci., 38: 2857-2863, 1997.
16. Rehemtulla, A., Stegman, L. D., Cardozo, S. J., Gupta, S., Hall, D. E., Contag, C. H., and Ross, B. D. Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia, 2: 491-495, 2000.
17. Harrington, K. J., Linardakis, E., and Vile, R. G. Transcriptional control: an essential component of cancer gene therapy strategies. Adv. Drug Delivery Rev., 44: 167-184, 2000.
18. Fussenegger, M. The impact of mammalian gene regulation concepts on functional genomic research, metabolic engineering, and advanced gene therapies. Biotechnol. Prog., 17: 1-51, 2001.
19. Nakagawa, S., Massie, B., and Hawley, R. G. Tetracycline-regulatable adenovirus vectors: pharmacologic properties and clinical potential. Eur. J. Pharm. Sci., 13: 53-60, 2001.
20. Dewanjee, M. K., Ghafouripour, A. K., Kapadvanjwala, M., Dewanjee, S., Serafini, A. N., Lopez, D. M., and Sfakianakis, G. N. Noninvasive imaging of c-myc oncogene messenger RNA with indium-111-antisense probes in a mammary tumor-bearing mouse model. J. Nucl. Med., 35: 1054-1063, 1994.
21. Cammilleri, S., Sangrajrang, S., Perdereau, B., Brixy, F., Calvo, F., Bazin, H., and Magdelenat, H. Biodistribution of iodine-125 tyramine transforming growth factor alpha antisense oligonucleotide in athymic mice with a human mammary tumour xenograft following intratumoral injection. Eur. J. Nucl. Med., 23: 448-452, 1996.
22. Phillips, J. A., Craig, S. J., Bayley, D., Christian, R. A., Geary, R., and Nicklin, P. L. Pharmacokinetics, metabolism, and elimination of a 20-mer phosphorothioate oligodeoxynucleotide (CGP 69846A) after intravenous and subcutaneous administration. Biochem. Pharmacol., 54: 657-668, 1997.
23. Tavitian, B., Terrazzino, S., Kuhnast, B., Marzabal, S., Stettler, O., Dolle, F., Deverre, J. R., Jobert, A., Hinnen, F., Bendriem, B., Crouzel, C., and Di Giamberardino, L. In vivo imaging of oligonucleotides with positron emission tomography. Nat. Med., 4: 467-471, 1998.
24. Tjuvajev, J. G., Joshi, A., Callegari, J., Lindsley, L., Joshi, R., Balatoni, J., Finn, R., Larson, S. M., Sadelain, M., and Blasberg, R. G. A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase. Neoplasia, 1: 315-320, 1999.
25. Yu, Y., Annala, A. J., Barrio, J. R., Toyokuni, T., Satyamurthy, N., Namavari, M., Cherry, S. R., Phelps, M. E., Herschman, H. R., and Gambhir, S. S. Quantification of target gene expression by imaging reporter gene expression in living animals. Nat. Med., 6: 933-937, 2000.
26. Doubrovin, M., Ponomarev, V., Beresten, T., Balatoni, J., Bornmann, W., Finn, R., Humm, J., Larson, S., Sadelain, M., Blasberg, R., and Gelovani Tjuvajev, J. Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo. Proc. Natl. Acad. Sci. USA, 98: 9300-9305, 2001.
27. Ponomarev, V., Doubrovin, M., Lyddane, C., Beresten, T., Balatoni, J., Bornman, W., Finn, R., Akhurst, T., Larson, S., Blasberg, R., Sadelain, M., and Tjuvajev, J. G. Imaging TCR-dependent NFAT-mediated T-cell activation with positron emission tomography in vivo. Neoplasia, 3: 480-488, 2001.
28. Naylor, L. H. Reporter gene technology: the future looks bright. Biochem. Pharmacol., 58: 749-757, 1999.
29. Gambhir, S. S., Bauer, E., Black, M. E., Liang, Q., Kokoris, M. S., Barrio, J. R., Iyer, M., Namavari, M., Phelps, M. E., and Herschman, H. R. A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. Proc. Natl. Acad. Sci. USA, 97: 2785-2790, 2000.
30. MacLaren, D. C., Gambhir, S. S., Satyamurthy, N., Barrio, J. R., Sharfstein, S., Toyokuni, T., Wu, L., Berk, A. J., Cherry, S. R., Phelps, M. E., and Herschman, H. R. Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals. Gene Ther., 6: 785-791, 1999.
31. 18F]fluoroethyl)spiperone: in vivo biochemical and kinetic characterization in rodents, nonhuman primates, and humans. J. Cereb. Blood Flow Metab., 9: 830-839, 1989.
32. Rogers, B. E., McLean, S. F., Kirkman, R. L., Della Manna, D., Bright, S. J., Olsen, C. C., Myracle, A. D., Mayo, M. S., Curiel, D. T., and Buchsbaum, D. J. In vivo localization of [(111)In]-DTPA-D-Phe1-octreotide to human ovarian tumor xenografts induced to express the somatostatin receptor subtype 2 using an adenoviral vector. Clin. Cancer Res., 5: 383-393, 1999.
33. Rogers, B. E., Zinn, K. R., and Buchsbaum, D. J. Gene transfer strategies for improving radiolabeled peptide imaging and therapy. Q. J. Nucl. Med., 44: 208-223, 2000.
34. Ur, E., Bomanji, J., Mather, S. J., Britton, K. E., Wass, J. A., Grossman, A. B., and Besser, G. M. Localization of neuroendocrine tumours and insulinomas using radiolabelled somatostatin analogues, 123I-Tyr3-octreotide and 111In-pentatreotide. Clin Endocrinol. (Oxf.), 38: 501-506, 1993.
35. Tjuvajev, J. G., Chen, S. H., Joshi, A., Joshi, R., Guo, R. S., Balatoni, J., Ballon, D., Koutcher, J., Finn, R., and Woo, S. L. Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo. Cancer Res., 59: 5186-5193, 1999.
36. Qiao, J., Doubrovin, M., Sauter, B. V., Huang, Y., Guo, Z. S., Balatoni, J., Akhurst, T., Blasberg, R. G., and Tjuvajev, J. G. Tumor-specific transcriptional targeting of suicide gene Ther. Gene Ther., 9: 168-175, 2002.
37. Bennett, J. J., Tjuvajev, J. G., Johnson, P., Doubrovin, M., Akhurst, T., Malhotra, S., Hackman, T., Balatoni, J., and Finn, R. Positron emission tomography imaging for herpes virus infection: implications for oncolytic viral treatments of cancer. Nat. Med., 7: 859-863, 2001.
38. Jacobs, A., Tjuvajev, J. G., Dubrovin, M., Akhurst, T., Balatoni, J., Beattie, B., Joshi, R., Finn, R., Larson, S. M., and Herrlinger, U. Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo. Cancer Res., 61: 2983-2995, 2001.
39. 124I]FIAU and PET. Molecular Imaging, 1: 36-42, 2002.
40. Yaghoubi, S. S., Wu, L., Liang, Q., Toyokuni, T., Barrio, J. R., Namavari, M., Satyamurthy, N., Phelps, M. E., Herschman, H. R., and Gambhir, S. S. Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors. Gene Ther., 8: 1072-1080, 2001.
41. Pelletier, S. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature, 334: 320, 1988.
42. Sachs, A. B., Sarnow, P., and Hentze, M. W. Starting at the beginning, middle, and end: translation initiation in eukaryotes. Cell, 89: 831-838, 1997.
43. Merritt, J. A., Roth, J. A., and Logothetis, C. J. Clinical evaluation of adenoviral-mediated p53 gene transfer: review of INGN 201 studies. Semin. Oncol., 28 (Suppl. 16): 105-114, 2001.