The Effect of Antiemetics on Pupillary Reflex Dilation during Epidural/General Anesthesia

Anesthesia and Analgesia

Volumn 97, Issue 6, 2003, Pages 1652-1656

  Larson, Merlin D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; CHLORPROMAZINE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DROPERIDOL; HALOPERIDOL; METOCLOPRAMIDE; ONDANSETRON; OPIATE;

ABDOMINAL SURGERY; ADULT; AGED; ANTIEMETIC ACTIVITY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DERMATOME; DRUG EFFECT; ELECTRIC CURRENT; EPIDURAL ANESTHESIA; FEMALE; GENERAL ANESTHESIA; HUMAN; MALE; MYDRIASIS; PRIORITY JOURNAL; PUPIL; PUPIL REFLEX;

EID: 0344420405     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000090011.19809.93     Document Type: Article

References (22)

1. Ashbury A. Pupil response to alfentanil and fentanyl: a study in patients anesthetized with halothane. Anaesthesia 1986;41:717-20.
2. Larson MD, Sessler DI, Washington DE, et al. Pupillary response to noxious stimulation during isoflurane and propofol anesthesia. Anesth Analg 1993;76:1072-8.
3. Larson MD, Kurz A, Sessler DI, et al. Alfentanil blocks reflex pupillary dilation in response to noxious stimulation but does not diminish the light reflex. Anesthesiology 1997;87:849-55.
4. Larson MD, Berry PD. Supraspinal pupillary effects of intravenous and epidural fentanyl during isoflurane anesthesia. Reg Anesth Pain Med 2000;25:60-6.
5. Loewenfeld IE. The pupil: anatomy, physiology and clinical applications. Detroit: Wayne State University Press, 1993:1566.
6. Larson MD, Sessler DI, Ozaki M, et al. Pupillary assessment of sensory block level during combined epidural-general anesthesia. Anesthesiology 1993;79:42-8.
7. Glantz SA. Primer of biostatistics. New York: McGraw-Hill, 2002.
8. Koss MC. Pupillary dilation as an index of central nervous system alpha 2 adrenergic activation. J Pharmacol Meth 1986;15:1-19.
9. Larson MD, Talke PO. Effect of dexmedetomidine, an alpha 2-adrenoceptor agonist, on human pupillary reflexes during general anaesthesia. Br J Clin Pharmacol 2001;51:27-33.
10. Wood M. Intravenous anesthetic agents. In: Drugs and anesthesia: pharmacology for anesthesiologists. Baltimore: Williams and Wilkins, 1982.
11. Kao YJ, Tellez J, Turner DR. Dose-dependent effect of metoclopramide on cholinesterases and suxamethonium metabolism. Br J Anaesth 1990;65:220-4.
12. Sharpe LG, Pickworth WB, Martin WR. Actions of amphetamine and antagonists on pupil diameter in the chronic sympathectomized dog. Psychopharmacology (Berl) 1977;53:115-20.
13. Bo P, Patrucco M, Savoldi F, et al. Behavioral and eegraphic changes induced by dopaminergic antidepressants in rabbits. Farmaco [Sci] 1985;40:608-16.
14. Potter DE, Ogidigben MJ, Chu TC. Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. Pharmacology 1998;57:249-60.
15. Bogdanski D, Sulser H, Brodie B. Comparative action of reserpine, tetrabenazine and chlorpromazine on central parasympathetic activity: effects on pupillary size and lacrimation in rabbit and on salivation in dog. J Pharmacol Exp Ther 1961;32:176-82.
16. Mekki QA, Turner P. Stimulation of dopamine receptors (type 2) lowers human intraocular pressure. Br J Ophthalmol 1985;69:909-10.
17. Preston KL, Sullivan JT, Strain EC, Bigelow GE. Effects of cocaine alone and in combination with bromocriptine in human cocaine abusers. J Pharmacol Exp Ther 1992;262:279-91.
18. Olschewski A, Hempelmann G, Vogel W, Safronov BV. Suppression of potassium conductance by droperidol has influence on excitability of spinal sensory neurons. Anesthesiology 2001;94:280-9.
19. Bach V, Carl P, Ravlo O, et al. Potentiation of epidural opioids with epidural droperidol: a one year retrospective study. Anaesthesia 1986;41:1116-9.
20. Driver RP Jr, D'Angelo R, Eisenach JC. Bolus metoclopramide does not enhance morphine analgesia after cesarean section. Anesth Analg 1996;82:1033-5.
21. Morgan MJ, Franklin KB. Dopamine receptor subtypes and formalin test analgesia. Pharmacol Biochem Behav 1991;40:317-22.
22. Larson MD, Sessler DI, Daniel M, Noorani M. Sympathetic nervous system does not mediate reflex pupillary dilation during desflurane anesthesia. Anesthesiology 1996;85:748-54.