A Novel Neuroimmune Mechanism in Cannabinoid-mediated Attenuation of Nerve Growth Factor-induced Hyperalgesia

Anesthesiology

Volumn 99, Issue 6, 2003, Pages 1391-1401

  Farquhar Smith, W Paul ^a   Rice, Andrew S C ^b  

^a ROYAL MARSDEN HOSPITAL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; ANANDAMIDE; CANNABINOID; CAPSAZEPINE; MYELOPEROXIDASE; NERVE GROWTH FACTOR; PALMIDROL; RIMONABANT; SR 141716 A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG MEGADOSE; DRUG RECEPTOR BINDING; DRUG WITHDRAWAL; ENZYMATIC ASSAY; HINDLIMB; HYPERALGESIA; INJECTION SITE; LATENT PERIOD; MALE; NEUROIMMUNOLOGY; NEUTROPHIL; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; THERMAL STIMULATION; TREATMENT FAILURE; WITHDRAWAL REFLEX;

ANALGESICS; ANIMALS; ARACHIDONIC ACIDS; CANNABINOIDS; CAPSAICIN; CELL MOVEMENT; HYPERALGESIA; MALE; NERVE GROWTH FACTOR; NEUTROPHILS; PIPERIDINES; POLYUNSATURATED ALKAMIDES; PYRAZOLES; RATS; RATS, WISTAR;

EID: 0344420333     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200312000-00024     Document Type: Article

References (48)

1. McMahon SB, Bennett DLH: Growth factors and pain, The Pharmcology of Pain. Edited by Dickenson AH, Besson JM. Berlin, Springer, 1997, pp 135-57
2. Shu X-Q, Mendell LM: Neurotrophins and hyperalgesia. Proc Natl Acad Sci USA 1999; 96:7693-6
3. Aloe L, Tuveri MA, Levi-Montalcini R: Studies on carrageenan-induced arthritis in adult rats: Presence of nerve growth factor and role of sympathetic innervation. Rheumatol Int 1992; 12:213-6
4. Woolf CJ, Safieh-Garabedian B, Ma Q-P, Crilly P, Winter J: Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity. Neuroscience 1994; 62:327-31
5. McMahon SB, Bennett DLH, Priestley JV, Shelton DL: The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule. Nat Med 1998; 1:774-80
6. Andreev NY, Dmitrieva N, Koltzenburg M, McMahon SB: Peripheral administration of nerve growth factor in the adult rat produces a thermal hyperalgesia that requires the presence of sympathetic post-ganglionic neurones. Pain 1995; 63:109-15
7. Amann R, Schuligoi R, Lanz I, Bernhard A, Peskar A: Effect of 5-lipoxygenase inhibitor on nerve growth factor-induced thermal hyperalgesia. Eur J Pharmacol 1996; 306:89-91
8. Amann R, Schuligoi R, Herzeg G, Donnerer J: Intraplantar injection of nerve growth factor into the rat hind paw: Local edema and effects on thermal nociceptive threshold. Pain 1995; 64:323-9
9. Bennett G, al Rashed S, Hoult JR, Brain SD: Nerve growth factor induced hyperalgesia in the rat hind paw is dependent on circulating neutrophils. Pain 1998; 77:315-22
10. Lewin GR, Rueff A, Mendell LM: Peripheral and central mechanisms of NGF-induced hyperalgesia. Eur J Neurosci 1994; 6:1903-12
11. Rueff A, Mendell LM: Nerve growth factor and NT-5 induce increase thermal sensitivity of cutaneous receptors in vivo. J Neurophysiol 1996; 76: 3593-6
12. Petersen M, Segond von Banchet G, Heppelmann B, Koltzenburg M: Nerve growth factor regulates the expression of bradykinin binding sites on adult sensory neurons via the neurotrophin receptor p75. Neuroscience 1998; 83: 161-8
13. Horigome K, Pryor JC, Bullock ED, Johnson EMJ: Mediator release from mast cells by nerve growth factor: Neurotrophin specificity and receptor mediation. J Biol Chem 1993; 268:14881-7
14. Tal M, Liberman R: Local injection of nerve growth factor (NGF) triggers degranulation of mast cells in rat paw. Neurosci Lett 1997; 221:129-32
15. Leon A, Buriani A, Dal Toso R, Fabris M, Romanello S, Aloe L, Levi-Montalcini R: Mast cells synthesize, store and release nerve growth factor. Proc Natl Acad Sci USA 1994; 91:3739-43
16. Aloc L, Leon A, Levi-Montalcini R: A proposod antacoid mechanism controlling mastocyte behaviour. Agents Actions 1993; 39:C145-7
17. Ramos BF, Zhang Y, Qureshi R, Jakschik BA: Mast cells are critical for the production of leukotrienes responsible for neutrophil recruitment in immune-complex-induced peritonitis in mice. J Immunol 1991; 147:1636-41
18. Rice ASC: Cannabinoids and pain. Curr Opin Investig Drugs 2001; 2:399-414
19. Tsou K, Brown S, Sañudo-Peña MC, Mackie K, Walker JM: Immunohistochemical distribution of cannabinoid receptors in the rat central nervous system. Neuroscience 1998; 83:393-411
20. Farquhar-Smith WP, Egertová M, Bradbury EJ, McMahon SB, Rice ASC, Elphick MR: Cannabinoid CB1 receptor expression in rat spinal cord. Mol Cell Neurosci 2000; 15:510-21
21. Calignano A, La Rana G, Guiffrida A, Piomelli D: Control of pain initiation by endogenous cannabinoids. Nature 1998; 394:277-81
22. Jaggar SI, Hasnie FS, Sellaturay S, Rice ASC: The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. Pain 1998; 76: 189-99
23. Richardson JD, Kilo S, Hargreaves KM: Cannabinoids reduce hyperalgesia and inflammation via interaction with peripheral CB1 receptors. Pain 1998; 75:111-9
24. Facci L, Dal Toso R, Romanello S, Buriani A, Skaper SD, Leon A: Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. Proc Natl Acad Sci USA 1995; 92:3376-80
25. Parolaro D: Presence and functional regulation of cannabinoid receptors in immune cells. Life Sci 1999; 65:637-44
26. 2-like receptors. Pain 2002; 97:11-21
27. Hargreaves K, Dubner R, Brown F, Flores C, Joris J: A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 1988; 32:77-88
28. Perkins MN, Campbell EA: Capsazepin reversal of the antinociceptive action of capsaicin in vivo. Br J Pharmacol 1992; 107:329-33
29. Saleh TS, Calixto JB, Medeiros YS: Effects of anti-inflammatory drugs upon nitrate and myeloperoxidase levels in the mouse pleurisy induced by carrageenan. Peptides 1999; 20:949-56
30. Bradley PP, Priebat DA, Christensen RD, Rothstein G: Measurement of cutaneous inflammation: Estimation of neutrophil content with an enzyme marker. J Invest Dermatol 1982; 78:206-9
31. Zygmunt PM, Petersson J, Andersson DA, Chuang H, Sorgard M, Di Marzo V, Julius D, Hogestatt ED: Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 1999; 400:452-7
32. Nicholas RS, Winter J, Wren P, Bergmann R, Woolf CJ: Peripheral inflammation increases the capsaicin sensitivity of dorsal root ganglion neurons in a nerve growth factor-dependent manner. Neuroscience 1999; 91:1425-33
33. Ramos BF, Qureshi R, Olsen KM, Jakschik BA: The importance of mast cells for the neutrophil influx in immune complex-induced peritonitis in mice. J Immunol 1990; 145:1868-73
34. Boyle MDP, Lawman JP, Gee AP, Young M: Nerve growth factor: A chemotactic factor for polymorphonuclear leukocytes in vivo. J Immunol 1985; 134:564-8
35. Ribeiro RA, Souza-Filho MV, Souza MH, Oliveira SH, Costa CH, Cunha FQ, Ferreira HS: Role of resident mast cells and macrophages in the neutrophil migration induced by LTB4, fMLP and C5a des arg. Int Arch Allergy Immunol 1997; 112:27-35
36. Schuligoi R: Effect of colchicine on nerve growth factor-induced leukocyte accumulation and thermal hyperalgesia in the rat. Naunyn-Schmiedebergs Arch Pharmacol 1998; 358:264-9
37. Levi-Montalcini R, Skaper SD, Dal Toso R, Petrelli L, Leon A: Nerve growth factor: From neurotrophin to neurokine. Trends Neurosci 1996; 19:514-20
38. Friedel RH, Schnurch H, Stubbusch J, Barde Y: Identification of genes differentially expressed by nerve growth factor and neurotrophin-3-dependent sensory neurones. Proc Natl Acad Sci USA 1997; 94:12670-5
39. Aley KO, Levine JD: Role of protein kinase A in the maintenance of inflammatory pain. J Neurosci 1999; 19:2181-6
40. Richardson JD, Aanonsen L, Hargreaves KM: Antihyperalgesic effects of spinal cannabinoids. Eur J Pharmacol 1998; 345:145-53
41. Showalter VM, Compton DR, Martin BR, Abood M: Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands. J Pharmacol Exp Ther 1996; 278:989-99
42. Calignano A, La Rana G, Piomelli D: Antinociceptive activity of the endogenous fatty acid amide, palmitoylethanolamide. Eur J Pharmacol 2001; 419:191-8
43. Lambert DM, Vandevoorde S, Jonsson K, Fowler CJ: The palmitoylethanolamide family: A new class of anti-inflammatory agents? Curr Med Chem 2002; 9:663-74
44. Mazzari S, Canella R, Petrelli L, Marcolongo G, Leon A: N-(2-hydroxyethyl) hexadecanamide is orally active in reducing edema formation and inflammatory hyperalgesia by down-modulating mast cell activation. Eur J Pharmacol 1996: 300:227-36
45. Audette CA, Burstein SH: Inhibition of leukocyte adhesion by the in vivo and in vitro administration of cannabinoids. Life Sci 1990; 47:753-9
46. Nichols RC, Vanderhoek JY: 5-hydroxyeicosanoids selectively stimulate the human neutrophil 15-lipoxygenase to use endogenous substrate. J Exp Med 1990; 171:367-75
47. Levine JD, Lam D, Taiwo YO, Donatoni P, Goetzl EJ: Hyperalgesic properties of 15-lipoxygenase products of arachidonic acid. Proc Natl Acad Sci USA 1986; 83:5331-4
48. Hwang SW, Cho H, Kwak J, Lee S, Kang C, Jung J, Cho S, Min KH, Suh Y, Kim D, Oh U: Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances. Proc Natl Acad Sci USA 2000; 97:6155-60