Isolation and characterization of an avirulent Candida albicans yeast monomorphic mutant

Medical Mycology

Volumn 41, Issue 1, 2003, Pages 43-52

  Iranzo, M ^a   Canizares J V ^a   Sainz Pardo I ^a   Aguado, C ^a   Ponton J ^b   Mormeneo, Salvador ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Candida albicans cell wall; Covalently linked proteins; Dimorphism and virulence; Wall epitopes; Yeast monomorphic mutant

Indexed keywords

CELL MEMBRANE PROTEIN; CHITIN; FUNGAL PROTEIN; GLUCAN; MANNAN; METHYLNITRONITROSOGUANIDINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1B12; MONOCLONAL ANTIBODY 3H8; N ACETYLGLUCOSAMINE; NITROGEN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; CONTROLLED STUDY; ELECTROPHORESIS; FUNGAL CELL; FUNGAL STRAIN; FUNGUS GROWTH; FUNGUS HYPHAE; FUNGUS ISOLATION; FUNGUS MUTANT; FUNGUS MUTATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MORPHOLOGY; MOUSE; MUTAGENESIS; MYCELIUM; NONHUMAN; PLATING MEDIUM; PROTEIN ANALYSIS; SERUM; STIMULATION; TEMPERATURE; VIRULENCE; YEAST;

ANIMALIA; CANDIDA; CANDIDA ALBICANS; FUNGI;

EID: 0344406869     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1080/mmy.41.1.43.52     Document Type: Article

References (38)

1. Calderone RA, Susuki S, Cannon R, et al. Candida albicans: Adherence, signalling and virulence. Med Mycol 2000; 38: 125-137.
2. Coleman D, Sullivan D, Bennett DE, et al. Candidiasis: The emergence of a novel species, Candida dublinensis. AIDS 1997; 11: 557-567.
3. De Bernardis F, Muhlschlegel FA, Cassone A, et al. The pH of the host niche controls gene expression in a virulence of Candida albicans. Infect Immun 1998; 66: 3317-3325.
4. Quindós G, San Millán R, Robert R, et al. Evaluation of Bichrolatex albicans, a new method for rapid identification of Candida albicans. J Clin Microbiol 1997; 35: 1263-1265.
5. Richardson MD. Fungal infections. In: McGee JOD, Isaacson PG, Wright A, eds. Oxford Textbook of Pathology. Oxford: Oxford University Press, 1992: 487-491.
6. Calderone RA, Fonzi WA. Virulence factors of Candida albicans. Trends Microbiol 2001; 9: 327-335.
7. Cutler JE. Putative virulence factors of Candida albicans. Annu Rev Microbiol 1991; 45: 187-218.
8. Bullawa CE, Miller DW, Henry LK, et al. Attenuated virulence of chitin-deficient mutants of Candida albicans. Proc Natl Acad Sci USA 1995; 92: 10570-10574.
9. Díez-Orejas R, Molero G, Navarro-García F, et al. Reduced virulence of Candida albicans MKC1 mutants: A role for mitogen-activated protein kinase in pathogenesis. Infect Immun 1997; 65: 833-837.
10. Shepherd MG, Poulter RTM, Sullivan PA. Candida albicans: Biology, genetics and pathogenicity. Ann Rev Microbiol 1985; 39: 599-614.
11. Chattaway FW, Holmes MR, Barlow AJF. Cell wall composition of the mycelial and blastospore forms of Candida albicans. J Gen Microbiol 1968; 51: 367-376.
12. Pontón J, Marot-Leblond A, Ezkurra PA, et al. Characterization of Candida albicans cell wall antigens with monoclonal antibodies. Infect Immunol 1993; 61: 4842-4847.
13. Cassone A, Ausiello CM, De Bernardis F, et al. The role of mannoproteins in pathogenicity and immune response to Candida albicans. In: Viva den Bossche H, Stevens, DA, Odds FC, eds. HostFungus Interplay. Bethesda, MD: National Foundation for Infectious Diseases, 1995: 26-36.
14. Sentandreu R, Mormeneo S, Ruíz-Herrera J. Biogenesis of the fungal cell wall. In: Wessels JGH, Meinhardt F, eds. The Mycota I: Growth, Differentiation and Sexuality. Berlin: Springer-Verlag, 1994: 111-124.
15. Leberer E, Harcus D, Broadbent ID, et al. Signal transduction through homologues of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans. Proc Natl Acad Sci USA 1996; 93: 13217-13222.
16. Lo HJ, Köller JR, DiDomenico B, et al. Nonfilamentous Candida albicans mutants are avirulent. Cell 1997; 90: 939-949.
17. Gale CA, Bendel CM, McClellan M, et al. Linkage of adhesion, filamentous growth and virulence in Candida albicans to a single gene INT1. Science 1998; 279: 1355-1358.
18. Staab JF, Bradway SD, Fidel PL, et al. Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1. Science 1999; 258: 1535-1538.
19. Ruíz-Herrera J, Iranzo M, Elorza MV, et al. Involvement of transglutaminase in the formation of covalent cross-links in the cell wall of Candida albicans. Arch Microbiol 1995; 164: 186-193.
20. Elorza MV, Murgui A, Sentandreu R. Dimorphism in Candida albicans: Contribution of mannoproteins to the architecture of yeast and mycelial cell walls. J Gen Microbiol 1985; 133: 2315-2325.
21. Lee K, Buckley HR, Campbell CC. An amino acid liquid synthetic medium for the development of mycelial and yeast forms of Candida albicans. Sabouraudia 1975; 13: 143-153.
22. Elorza MV, Sentandreu R, Ruíz-Herrera J. Isolation and characterisation of monomorphic mutants of Candida albicans. J Bacteriol 1994; 176: 2318-2325.
23. Simonetti B, Strippoli V, Cassone A. Yeastmycelial conversion induced by N-acetyl-glucosamine in Candida albicans. Nature (London) 1974; 250: 344-346.
24. Elorza MV, Sentandreu R. Effect of cycloheximide on yeast wall synthesis. Biochem Biophys Res Commun 1969; 36: 741-747.
25. Marcilla A, Elorza MV, Mormeneo S, et al. Candida albicans mycelial wall structure: Supramolecular complexes released by Zymolyase, chitinase and β-mercaptoethanol. Arch Microbiol 1991; 155: 312-319.
26. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 1970; 227: 680-686.
27. Towbin H, Stahelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Natl Acad Sci USA 1979; 76: 4350-4353.
28. Burnette WN. Western blotting: Electrophoretic transfer of proteins from sodium dodecyl sulphatepolyacrylamide to unmodified nitro-cellulose and radiographic detection with antibody and radioidinated protein A. Anal Biochem 1985; 112: 195-203.
29. Marcilla A, Mormeneo S, Elorza MV, et al. Wall formation by Candida albicans yeast cells: Synthesis, secretion and incorporation of two types of mannoproteins. J Gen Microbiol 1993; 139: 2985-2993.
30. Marcilla A, Monteagudo C, Mormeneo S, et al. Monoclonal antibody 3H8: A useful tool in the diagnosis of candidiasis. Microbiology 1999; 145: 695-701.
31. Mormeneo S, Rico H, Iranzo M, et al. Study of supramolecular structures released from the cell wall of Candida albicans by ethylenediamine treatment. Arch Microbiol 1996; 166: 327-335.
32. Kauffman SHE, Schoel B. Heat shock proteins as antigens in immunity against infection and self. In: Morimoto RI., Tissiers A, Georgopov G, eds. The Biology of Heat Shock Proteins and Molecular Chaperones. Cold Spring Harbor, NY: Cold Spring Harbor Press, 1994: 495-531.
33. Monteagudo C, Marcilla A, Mormeneo S, et al. Specific immunohistochemical identification of Candida albicans in paraffin-embedded tissue with a new monoclonal antibody (1B12). Am J Clin Pathol 1995; 103: 130-135.
34. Freydiè AM, Buchaille L, Guinet R, et al. Evaluation of latex reagents for rapid identification of Candida albicans and C. krusei colonies. J Clin Microbiol 1997; 35: 877-880.
35. Robert R, Sentandreu R, Bernard C, et al. Evaluation du réactif Bichro-latex albicans pour l'identification rapide de colonies de Candida albicans. J Mycol Med 1994; 4: 226-229.
36. Torsantucci A, Gomez MJ, Bromuro C, et al. Biochemical and antigenic characterisation of mannoprotein constituents released from yeast and mycelial forms of Candida albicans. J Med Vet Mycol 1991; 29: 361-372.
37. Munro CA, Schofield DA, Gooday DW, et al. Regulation of chitin synthesis during dimorphic growth of Candida albicans. Microbiology 1998: 144: 391-401.
38. Buurman ET, Westwater C, Hube B, et al. Molecular analysis of CaMnt1p, a mannosyl transferase important for adhesion and virulence of Candida albicans. Proc Natl Acad Sci USA 1998; 95: 7670-7675.