On a fallacious invocation of the Barker hypothesis of anomalies in newborn rats due to mothers' food restriction in preimplantation phases

Reproductive BioMedicine Online

Volumn 7, Issue 5, 2003, Pages 580-582

  Walters, Eurof ^a   Edwards, Robert G ^b  

^a CHURCHILL COLLEGE   (United Kingdom)

^b Reproductive BioMedicine Online   (United Kingdom)

Author keywords

Barker hypothesis; Mice; Rebuttal; Statistical error

Indexed keywords

ANALYTICAL ERROR; ARTICLE; BIRTH DEFECT; DATA ANALYSIS; DEVELOPMENTAL DISORDER; DIET RESTRICTION; EMBRYO; EMBRYO GROWTH; FETUS RISK; HYPOTHESIS; LOW BIRTH WEIGHT; MATERNAL NUTRITION; MEDICAL LITERATURE; NIDATION; NONHUMAN; PREIMPLANTATION EMBRYO; PROTEIN RESTRICTION; RAT; STATISTICAL ANALYSIS;

EID: 0344393437     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-6483(10)62075-5     Document Type: Article

References (15)

1. Barker DJP 1994 Mothers, Babies and Disease in Later Life. BMJ Publishing, London.
2. Bloomfield FH, Oliver MH, Hawkins P et al. 2003 A periconceptional nutritional origin for noninfectious preterm birth. Science 300, 606.
3. Cox GF, Burger J, Lip V et al. 2002 Intracytoplasmic sperm injection may increase the risk of imprinting defects. American Journal of Human Genetics 71, 162-164.
4. Edwards RG, Ludwig M 2003 Are major defects in children conceived in vitro due to innate problems in patients or to induced genetic damage? Reproductive BioMedicine Online 7, 131-138.
5. Edwards CR, Benediktsson R, Lindsay RS, Seckl JR 1993 Dysfunction of glucocorticoid barrier: link between foetal environment and hypertension. Lancet 341, 355-357.
6. Hansen M, Kurinczuk JJ, Bower C et al. 2002 The risk of major birth defects after intracytoplasmic sperm injection and in vitro fertilization. New England Journal of Medicine 46, 725-730.
7. Kwong WY, Wild AE, Roberts P et al. 2000 Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension. Development 127, 4195-4202.
8. Ludwig M, Schröder AK, Diedrich K 2001 Impact of intracytoplasmic sperm injection on the activation and fertilization process of oocytes. Reproductive BioMedicine Online 3, 230-240.
9. Moll AC, Imhof SM, Cruysberg RM et al. 2003 Incidence of retinoblastoma in children born after in vitro fertilization. Lancet 361, 309-310.
10. Ørstavik KH, Eiklid K, van der Hagen CB et al. 2003 Another case of an imprinting defect in a girl with Angelman syndrome who was conceived by intracytoplasmic sperm injection. American Journal of Human Genetics 72, 218-219.
11. Rutledge JC, Generoso WM, Shourbajid A et al. 1992 Developmental anomalies arising from exposure of zygotes and first cleavage embryos to mutagens. Mutation Research 296, 166-177.
12. Schieve LA, Meikle SF, Ferre C et al. 2002 Low and very low birthweight in infants conceived with the use of assisted reproductive technology. New England Journal of Medicine 346, 731-737.
13. Walters DE 1994 A plea for a more fastidious and objective use of statistics, Journal of Assisted Reproduction and Genetics 11, 63-73.
14. Walters DE 2000 On the need for statistical rigour when pooling data from a variety of sources. Human Reproduction 15, 1205-1208.
15. Walters DE 2002 'Uneasy Science' - the pooling of heterogeneous data. Fertility and Sterility 77, 1374-1309.