Elimination of the Disulfide Bridge in the Rieske Iron-Sulfur Protein Allows Assembly of the [2Fe-2S] Cluster into the Rieske Protein but Damages the Ubiquinol Oxidation Site in the Cytochrome bc1 Complex

Biochemistry

Volumn 42, Issue 46, 2003, Pages 13637-13645

  Merbitz Zahradnik, Torsten ^a   Zwicker, Klaus ^b   Nett, Jürgen H ^a   Link, Thomas A ^c   Trumpower, Bernard L ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; ELECTRONIC STRUCTURE; IRON COMPOUNDS; OXIDATION; YEAST;

CYSTEINES; MUTANTS;

PROTEINS;

3 UNDECYL 2 HYDROXYDIOXOBENZOTHIAZOLE; BENZOTHIAZOLE DERIVATIVE; CITRININ; CYSTEINE; DISULFIDE; IRON DERIVATIVE; IRON SULFUR PROTEIN; LEUCINE; MENADIOL; METAL COMPLEX; MUTANT PROTEIN; QUINOLINE DERIVATIVE; STIGMATELLIN; TYROSINE DERIVATIVE; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING KINETICS; CHEMICAL STRUCTURE; DISULFIDE BOND; DRUG PROTEIN BINDING; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; NONHUMAN; OXIDATION KINETICS; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; REDUCTION KINETICS; SACCHAROMYCES CEREVISIAE; THERMODYNAMICS; WESTERN BLOTTING; WILD TYPE; YEAST;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; BLOTTING, WESTERN; CYSTEINE; DISULFIDES; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTRON TRANSPORT COMPLEX III; IRON-SULFUR PROTEINS; MITOCHONDRIA; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; POTENTIOMETRY; RECOMBINANT PROTEINS; UBIQUINONE; YEASTS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0344391926     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035344r     Document Type: Article

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