Long-range genomic rearrangements upstream of Kit dysregulate the developmental pattern of Kit expression in W57 and W(banded) mice and interfere with distinct steps in melanocyte development

Development

Volumn 124, Issue 1, 1997, Pages 65-77

  Klüppel, Michael ^a,b   Nagle, Deborah L ^c,d   Bucan, Maja ^c   Bernstein, Alan ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Dominant white spotting; Genomic rearrangement; Kit; Melanocyte; Melanogenesis; Mouse; Steel; Transcriptional regulation

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DERMATOME; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENE REARRANGEMENT; MELANOCYTE; MELANOGENESIS; MOUSE; MOUSE MUTANT; NONHUMAN; ONCOGENE C KIT; PRIORITY JOURNAL; RECEPTOR GENE; SKIN PIGMENTATION; SOMITE; TRANSCRIPTION INITIATION;

ALLELES; ANIMALS; BONE MARROW CELLS; CELLS, CULTURED; CHROMOSOME MAPPING; DNA PRIMERS; EMBRYONIC AND FETAL DEVELOPMENT; GENE REARRANGEMENT; GENES, REGULATOR; GENETIC MARKERS; GESTATIONAL AGE; INVERSION, CHROMOSOME; MAST CELLS; MELANOCYTES; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-KIT; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RECEPTORS, GABA; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SEQUENCE DELETION; TRANSCRIPTION, GENETIC;

EID: 0344352509     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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