Pharmacokinetics and blood-brain barrier transport of an anti- transferrin receptor monoclonal antibody (OX26) in rats after chronic treatment with the antibody
ANIMAL EXPERIMENT;
ANIMAL MODEL;
AREA UNDER THE CURVE;
ARTICLE;
BLOOD BRAIN BARRIER;
CONTROLLED STUDY;
DRUG BIOAVAILABILITY;
DRUG DELIVERY SYSTEM;
INTRAVENOUS DRUG ADMINISTRATION;
MALE;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
RECEPTOR DOWN REGULATION;
TISSUE CULTURE;
ANIMALS;
ANTIBODIES, MONOCLONAL;
AREA UNDER CURVE;
BLOOD-BRAIN BARRIER;
INJECTIONS, INTRAVENOUS;
MALE;
MICE;
RATS;
RATS, SPRAGUE-DAWLEY;
RECEPTORS, TRANSFERRIN;
Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells
Descamps L, Dehouck M-P, Torpier G and Cecchelli R (1996) Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells. Am J Physiol 270:H1149-H1158.
Pharmacokinetics and saturable blood-brain barrier transport of biotin bound to a conjugate of avidin and a monoclonal antibody to the transferrin receptor
Kang Y-S, Bickel U and Pardridge WM (1994) Pharmacokinetics and saturable blood-brain barrier transport of biotin bound to a conjugate of avidin and a monoclonal antibody to the transferrin receptor. Drug Metab Dispos 22:99-105.
Use of neutral-avidin improves pharmacokinetics and brain delivery of biotin bound to an avidin-monoclonal antibody conjugate
Kang Y-S and Pardridge WM (1994) Use of neutral-avidin improves pharmacokinetics and brain delivery of biotin bound to an avidin-monoclonal antibody conjugate. J Pharmacol Exp Ther 269:344-350.
Differential effects of transferrin receptor antibodies on growth and receptor expression of human lymphocytic and myelocytic cell lines
Keyna U, Platzer E, Woith W, Nusslein I, Kalden JR and Manger B (1994) Differential effects of transferrin receptor antibodies on growth and receptor expression of human lymphocytic and myelocytic cell lines. Eur J Haematol 52:169-175.
Expression and upregulation of transferrin receptors and iron uptake in the epiplexus cells of different aged rats injected with lipopolysaccharide and interferon-gamma
Lu J, Kaur C and Ling E-A (1995) Expression and upregulation of transferrin receptors and iron uptake in the epiplexus cells of different aged rats injected with lipopolysaccharide and interferon-gamma. J Anat 187:603-611.
National Institutes of Health Publication 85-23. National Institutes of Health, Bethesda, MD
National Institutes of Health (1985) Principles of Laboratory Animal Care, National Institutes of Health Publication 85-23. National Institutes of Health, Bethesda, MD.
Selective transport of anti-transferrin receptor antibody through the blood-brain barrier in vivo
Pardridge WM, Buciak JL and Friden PM (1991) Selective transport of anti-transferrin receptor antibody through the blood-brain barrier in vivo. J Pharmacol Exp Ther 259:66-70.
Quantification of rat hepatocyte transferrin receptors with poly- And monoclonal antibodies and protein A
Rudolph JR, Regoeczi E and Southward S (1988) Quantification of rat hepatocyte transferrin receptors with poly-and monoclonal antibodies and protein A. Histochemistry 88:187-192.
Combinations of anti-transferrin receptor monoclonal antibodies inhibit human tumor cell growth in vitro and in vivo: Evidence for synergistic antiproliferative effects
White S, Taetle R, Seligman PA, Rutherford M and Trowbridge IS (1990) Combinations of anti-transferrin receptor monoclonal antibodies inhibit human tumor cell growth in vitro and in vivo: evidence for synergistic antiproliferative effects. Cancer Res 50:6295-6301.