Genetic variation in the dimorphic regions of rap-1 genes and rap-1 loci of Babesia bigemina

Molecular and Biochemical Parasitology

Volumn 90, Issue 2, 1997, Pages 479-489

  Hötzel, Isidro ^a   Suarez, Carlos E ^a   McElwain, Terry F ^a   Palmer, Guy H ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Babesia bigemina; Babesia bovis; Multigene family; RAP 1; Rhoptry

Indexed keywords

ANTIGEN; VACCINE;

AMINO TERMINAL SEQUENCE; ARGENTINA; ARTICLE; BABESIA; CARBOXY TERMINAL SEQUENCE; CATTLE; CONTROLLED STUDY; GENE CONVERSION; GENE LOCUS; GENE SEQUENCE; GENETIC VARIABILITY; IMMUNE RESPONSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN VARIANT; PUERTO RICO; STRAIN DIFFERENCE;

AMINO ACID SEQUENCE; ANIMALS; BABESIA; BABESIA BOVIS; BASE SEQUENCE; BLOTTING, SOUTHERN; CONSERVED SEQUENCE; DNA, PROTOZOAN; GENES, PROTOZOAN; GENOME, PROTOZOAN; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PROTOZOAN PROTEINS; RESTRICTION MAPPING; SEQUENCE ANALYSIS, DNA; VARIATION (GENETICS);

ANIMALIA; BABESIA; BABESIA BIGEMINA; BABESIA BOVIS; BOS TAURUS; PROTOZOA; VIBRIO PHAGE NT-1;

EID: 0344352464     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(97)00182-5     Document Type: Article

References (20)

1. Perkins M.E. Rhoptry organelles of apicomplexan parasites. Parasitol. Today. 8:1992;28-32.
2. McElwain T.F., Perryman L.E., Musoke A.J., McGuire T.C. Molecular characterization and immunogenicity of neutralization-sensitive Babesia bigemina merozoite surface proteins. Mol. Biochem. Parasitol. 47:1991;213-222.
3. McElwain T.F., Perryman L.E., Davis W.C., McGuire T.C. Antibodies define multiple proteins with epitopes exposed on the surface of live Babesia bigemina merozoites. J. Immunol. 138:1987;2298-2304.
4. Machado R.Z., McElwain T.F., Suarez C.E., Hines S.A., Palmer G.H. Babesia bigemina: Isolation and characterization of merozoite rhoptries. Exp. Parasitol. 77:1993;315-325.
5. Mishra V.S., McElwain T.F., Dame J.B., Stephens E.B. Isolation, sequence and differential expression of the p58 gene family of Babesia bigemina. Mol. Biochem. Parasitol. 53:1992;149-158.
6. Figueroa J.V., Buening G.M. In vitro inhibition of multiplication of Babesia bigemina by using monoclonal antibodies. J. Clin. Microbiol. 29:1991;997-1003.
7. + T-helper lymphocyte epitopes in the Babesia bigemina rhoptry associated protein-1. Mol. Biochem. Parasitol. 81:1996;89-99.
8. + T-helper lymphocyte responses against Babesia bigemina rhoptry-associated protein 1. Infect. Immun. 64:1996;2079-2087.
9. Madruga C.R., Suarez C.E., McElwain T.F., Palmer G.H. Conservation of merozoite membrane and apical complex B-cell epitopes among Babesia bigemina and Babesia bovis strains isolated in Brazil. Vet. Parasitol. 61:1996;21-30.
10. Echaide I.E., de Echaide S.T., Guglielmone A.A. Live and soluble antigens for cattle protection to Babesia bigemina. Vet. Parasitol. 51:1993;35-40.
11. Vidotto O., McElwain T.F., Machado R.Z., Perryman L.E., Suarez C.E., Palmer G.H. Babesia bigemina: Identification of B-cell epitopes associated with parasitized erythrocytes. Exp. Parasitol. 81:1996;491-500.
12. Dalrymple B.P., Casu R.E., Peters J.M., Dimmock C.M., Gale K.R., Boese R., Wright I.G. Characterisation of a family of multi-copy genes encoding rhoptry protein homologues in Babesia bovis, Babesia ovis and Babesia canis. Mol. Biochem. Parasitol. 57:1993;181-192.
13. Suarez C.E., McElwain T.F., Stephens E.B., Mishra V.S., Palmer G.H. Sequence conservation among merozoite apical complex proteins of Babesia bovis, Babesia bigemina and other apicomplexa. Mol. Biochem. Parasitol. 49:1991;329-332.
14. Suarez C.E., McElwain T.F., Echaide I., Torioni de Echaide S., Palmer G.H. Interstrain conservation of babesial RAP-1 surface-exposed B-cell epitopes despite rap-1 genomic polymorphism. Infect. Immun. 62:1994;3576-3579.
15. Meyerhans A., Vartanian J.P., Wain-Hobson S. DNA recombination during PCR. Nucleic Acids Res. 18:1990;1687-1691.
16. Graham G.J. Tandem genes and clustered genes. J. Theor. Biol. 175:1995;71-87.
17. Adams J.H., Hudson D.E., Torii M., Ward G.E., Wellems T.E., Aikawa M., Miller L.H. The Duffy receptor family of Plasmodium knowlesi is located within the micronemes of invasive malaria merozoites. Cell. 63:1990;141-153.
18. Chitnis C.E., Miller L.H. Identification of the erythrocyte binding domains of Plasmodium vivax and Plasmodium knowlesi proteins involved in erythrocyte invasion. J. Exp. Med. 180:1994;497-506.
19. Prickett M.D., Smarz T.R., Adams J.H. Dimorphism and intragenic recombination within the microneme protein (MP-1) gene family of Plasmodium knowlesi. Mol. Biochem. Parasitol. 63:1994;37-48.
20. Haynes J.D., Dalton J.P., Klotz F.W., McGuinniss M.H., Hadley T.J., Hudson D.E., Miller L.H. Receptor-like specificity of a Plasmodium knowlesi malarial protein that binds to Duffy antigen ligands on erythrocytes. J. Exp. Med. 167:1988;1873-1881.