The TATA-less, GC-rich porcine dipeptidylpeptidase IV (DPPIV) promoter shows bidirectional activity

Biological Chemistry

Volumn 379, Issue 1, 1998, Pages 75-81

  Qvist, Hanne ^a   Sjöström, Hans ^a   Norén, Ove ^a  

^a NONE

Author keywords

5' flanking region; Bidirectional promoter activity; CpG island; Dipeptidylpeptidase IV; DPPIV; TATA less

Indexed keywords

DIPEPTIDYL PEPTIDASE IV; INTESTINE ENZYME;

ARTICLE; BRUSH BORDER; CELL STRAIN CACO 2; CONSENSUS SEQUENCE; DNA FLANKING REGION; DNA SEQUENCE; GENE DELETION; GENE STRUCTURE; GENETIC TRANSFECTION; HEP 2 CELL; HEPATOMA CELL; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SOUTHERN BLOTTING; TATA BOX; TRANSCRIPTION INITIATION; TRANSLATION INITIATION;

ANIMALS; ANTIGENS, CD26; BASE SEQUENCE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CLONING, MOLECULAR; GENES, REPORTER; HUMANS; MICROVILLI; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; SWINE; TATA BOX; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

SUIDAE;

EID: 0344351836     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Abbott, C.A., Baker, E., Sutherland, G.R., and McCaughan, G.W. (1994). Genomic organization, exact localization, and tissue expression of the human CD26 (dipeptidylpeptidase IV) gene. Immunogen. 40, 331-338.
2. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., Struhl, K., Albright, L.M., Coen, D.M., and Varki, A. (1995). Current Protocols in Molecular Biology. (New York: John Wiley and Sons, Inc.)
3. Bernard, A., Mattei, M., Pierres, M., and Marguet, D. (1994). Structure of the mouse dipeptidylpeptidase IV (CD26) gene. Biochem. 33, 15204-15214.
4. Böhm, S.K., Gum, J.R., Erickson, R.H., Hicks, J.W., and Kim, Y.S. (1995). Human dipeptidylpeptidase IV gene promoter: Tissue-specific regulation from a TATA-less GC-rich sequence characteristic of a housekeeping gene promoter. Biochem. J. 311, 835-843.
5. Chomczynski, P., and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
6. Erickson, R.H., and Kim, Y.S. (1990). Digestion and absorption of dietary protein. Ann. Rev. Med. 41, 133-139.
7. Farnham, P.J., Abrams, J.M., and Schimke, R.T. (1985). Opposite-strand RNAs from the 5′-flanking region of the mouse dihydrofolate reductase gene. Proc. Natl. Acad. Sci. USA 82, 3978-3982.
8. Fleischer, B. (1987). A novel pathway of human T cell activation via a 103 kD T cell activation antigene. J. Immunol. 138, 1346-1350.
9. Fujii, H., and Shimada, T. (1989). Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene. J. Biol. Chem. 264, 10057-10064.
10. Genersch, E., Eckerskorn, C., Lottspeich, F., Herzog, C., Kühn, K., and Pöschl, E. (1995). Purification of the sequence-specific transcription factor CTCBF, involved in the control of human collagen IV genes: subunits with homology to Ku antigen. EMBO J. 14, 791-800.
11. Gardiner-Garden, M., and Frommer, M. (1987). CpG islands in vertebrate genomes. J. Mol. Biol. 196, 261-282.
12. Gavalas, A., and Zalkin, H. (1995). Analysis of the chicken GRAT/ AIRC bidirectional promoter for de novo purine nucleotide synthesis. J. Biol. Chem. 270, 2403-2410.
13. Gavalas, A., Dixon, J.E., Brayton, K.A., and Zalkin, H. (1993). Coexpression of two closely linked avian genes for purine nucleotide synthesis from a bidirectional promoter. Mol. Cell. Biol. 13, 4784-4792.
14. Gorman, C.M., Moffat, L.F., and Howard, B.H. (1982). Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2, 1044-1051.
15. Gorvel, J.P., Ferrero, A., Chambraud, L., Rigal, A., Bonicel, J., and Maroux, S. (1991). Expression of the sucrase-isomaltase and dipeptidylpeptidase IV in human small intestine and colon. Gastroenterology 101, 618-625.
16. Hansen, G.H., Niels-Christiansen, L.L., Poulsen, M.D., Norén, O., and Sjöström, H. (1994). Distribution of three microvillar enzymes along the small intestinal crypt-villus axis. J. Submicroscopic Cytol. Pathol. 26, 453-460.
17. Kenny, A.J., Booth, A.G., George, S.G., Ingram, J., Kershaw, J., Wood, E.J., and Young, A.R. (1976). Dipeptidylpeptidase IV, a kidney brush border serine peptidase. Biochem. J. 157, 169-182.
18. Knowles, B.B., Howe, C.C., and Aden, D.P. (1980). Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209, 497-499.
19. Liao, W., Ash, J., and Johnson, L.F. (1994). Bidirectional promoter of the mouse thymidylate synthase gene. Nucl. Acids Res. 22, 4044-4049.
20. Linton, J.P., Yen, J.J., Selby, E., Chen, Z., Chinsky, J.M., Liu, K., Kellems, R.E., and Crouse, G.F. (1989). Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of divergently transcribed Rep-1 gene. Mol. Cell. Biol. 9, 3058-3072.
21. Miyamoto, Y., Ganapathy, V., Barlas, A., Neubert, K., Barth, A., and Leibach, F.H. (1987). Role of dipeptidylpeptidase IV in uptake of peptide nitrogen from β-casomorphin in rabbit renal BBMV. Am. J. Physiol. 252, F670-F677.
22. Olsen, J., Sjöström, H., and Norén, O. (1989). Cloning of the pig aminopeptidase N gene. FEBS Lett. 1, 2, 275-281.
23. Olsen, J., Laustsen, L., Kärnström, U., Sjöström, H., and Norén, O. (1991). Tissue-specific interactions between nuclear proteins and the aminopeptidase N promoter. J. Biol. Chem. 266, 18089-18096.
24. Olsen, J., Laustsen, L., and Troelsen, J. (1994). HNF1α activates the aminopeptidase N promoter in intestinal (Caco-2) cells. FEBS Lett. 342, 325-328.
25. Olsen, J., Classen-Linke, I., Sjöström, H., and Norén, O. (1995). Pseudopregnancy induces the expression of hepatocyte nuclear factor-1β and its target gene aminopeptidase N in rabbit endometrium via the epithelial promoter. Biochem. J. 312, 31-37.
26. Olsen, J., Kokholm, K., Troelsen, J.T., and Laustsen, L. (1997). An enhancer with cell-type dependent activity is located between the myeloid and epithelial aminopeptidase N (CD13) promoters. Biochem. J. 322, 899-908.
27. Pinto, M., Robine-Leon, S., Appay, M., Kedinger, M., Triadou, N., Dussaulx, E., Lacroix, B., Simon-Assermann, P., Haffen, K., Fogh, J., and Zweibaum, A. (1983). Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture. Biol. Cell 47, 323-330.
28. Pöschl, E., Pollner, R., and Kühl, K. (1988). The genes for the α1(IV) and α2(IV) chains of human basement membrane collagen type IV are arranged head-to-head and separated by a bidirectional promoter of unique structure. EMBO J. 7, 2687-2695.
29. Sanger, F., Nicklen, S., and Coulson, A.R. (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74, 5463-5467.
30. Schilling, L.J., and Farnham, P.J. (1995). The bidirectionally transcribed dihydrofolate reductase and Rep-3a promoters are growth regulated by distinct mechanisms. Cell Growth and Diff. 6, 541-548.
31. Schmidt, C., Fischer, G., Kadner, H., Genersch, E., Kühn, K., and Pöschl, E. (1993). Differential effects of DNA-binding proteins on bidirectional transcription from the common promoter region of human collagen type IV genes COL4A1 and COL4A2. Biochim. Biophys. Acta 1174, 1-10.
32. Shapiro, L.H., Ashmun, R.A., Roberts, W.M., and Look, A.T. (1991). Separate promoters control transcription of the human aminopeptidase N gene in myeloid and intestinal epithelial cells. J. Biol. Chem. 266, 11999-12007.
33. Shimada, T., Fujii, H., and Lin, H. (1989). A 165-Base pair sequence between the dihydrofolate reductase gene and the divergently transcribed upstream gene is sufficient for bidirectional transcriptional activity. J. Biol. Chem. 264, 20171-20174.
34. Thomsen, P.D., Qvist, H., Marklund, L., Andersson, L., Sjöström, H., and Norén, O. (1993). Assignment of the dipeptidylpeptidase IV (DPPIV) gene to pig chromosome 15q21. Mammal. Genome 4, 604-607.
35. Troelsen, J.T., Olsen, J., Norén, O., and Sjöström, H. (1992). A novel intestinal trans-factor (NF-LPH1) interacts with the lactase-phlorizin hydrolase promoter and co-varies with the enzymatic activity. J. Biol. Chem. 267, 20407-20411.
36. Troelsen, J.T., Mehlum, A., Olsen, J., Spodsberg, N., Hansen, G.H., Prydz, H., Norén, O., and Sjöström, H. (1994a). 1 kb of the lactase-phlorizin hydrolase promoter directs post-weaning decline and small intestinal-specific expression in transgenic mice. FEBS Lett. 342, 291-296.
37. Troelsen, J.T., Olsen, J., Mitchelmore, C., Hansen, G., Sjöström, H., and Norén, O. (1994b). Two intestinal specific nuclear factors binding to the lactase-phlorizin hydrolase and sucrase promoters are functionally related oligomeric molecules. FEBS Lett. 342, 297-301.
38. Ulmer, A.J., Mattern, T., Feller, A.C., Heymann, E., and Flad, H.D. (1990). CD26 antigen is a surface dipeptidylpeptidase IV (DPP IV) as characterized by monoclonal antibodies clone TII-19-4-7 and 4EL1C7. Scand. J. Immunol. 31, 429-435.