The relationship between c-erbB-2 oncogene expression and clinicopathological factors in gastric cancer

Journal of International Medical Research

Volumn 27, Issue 2, 1999, Pages 74-78

  Gurel S ^a   Dolar, E ^a   Yerci, O ^a   Samli, B ^a   Ozturk H ^a   Nak, S G ^a   Gulten M ^a   Memik, F ^a  

^a ULUDAG UNIVERSITY   (Turkey)

Author keywords

c erbB 2 oncoprotein; Clinicopathological features; Gastric carcinoma; Prognosis

Indexed keywords

FORMALDEHYDE; PARAFFIN;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER MORTALITY; CANCER STAGING; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; GASTRECTOMY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; ONCOGENE C ERB; PATHOLOGY; PROGNOSIS; RETROSPECTIVE STUDY; STAINING; STOMACH CANCER; TISSUE SECTION; TURKEY (REPUBLIC);

EID: 0344348912     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/030006059902700203     Document Type: Article

References (11)

1. Marubini E, Bonafanti G, Bozzetti F, et al: A prognostic score for patients resected for gastric cancer. Eur J Cancer 1993; 29A: 845-850.
2. Hirohashi S, Sugimura T: Genetic alterations in human gastric cancer. Cancer Cells 1991; 3: 49-52.
3. Uchino S, Tsuda H, Maruyama K, et al: Overexpression of c-erbB-2 protein in gastric cancer. Cancer 1993; 72: 3179-3184.
4. Yokoto J, Yamamoto T, Miyajima N, et al: Genetic alterations of the c-erbB-2 oncogene occur frequently in tubular adenocarcinoma of the stomach and are often accompanied by amplification of the v-erbA homologue. Oncogene 1988; 2: 283-287.
5. Falck VG, Gullick WJ: c-erbB-2 oncogene product staining in gastric adeno-carcinoma. An immunohistochemical study. J Pathol 1989; 159: 107-111.
6. Lemoine NR, Jain S, Silvestre F, et al: Amplification and overexpression of the EGF receptor and c-erbB-2 proto-oncogenes in human stomach cancer. Br J Cancer 1991; 64: 79-83.
7. Park J-B, Rhim JS, Park S-C, et al: Amplification, overexpression and rearrangement of the c-erbB-2 protooncogene in primary human stomach carcinomas. Cancer Res 1989; 49: 6605-6609.
8. Tsuda H, Hirohashi S, Shimosato Y, et al: Immunohistochemical study on overexpression of c-erbB-2 protein in human breast cancer: its correlation with gene amplification and long-term survival of patients. Jpn J Cancer Res 1990; 81: 327-332.
9. Wright C, Angus B, Nicholson S, et al: Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer. Cancer Res 1989; 49: 2087-2090.
10. Maruyama K. The most important prognostic factors for gastric cancer patients. Scand J Gastroenterol 1987; 22: 63-68.
11. Jain S, Filipe MI, Gullick WJ, et al: c-erbB-2 proto-oncogene expression and its relationship to survival in gastric carcinoma: an immunohistochemical study on archival material. Int J Cancer 1981; 48: 668-671.