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Volumn 13, Issue 3, 1999, Pages 213-222

New cytotoxic epidithiodioxopiperazines related to verticillin A from a marine isolate of the fungus Penicillium

Author keywords

Cytotoxic dioxopiperazines; Epidithiodioxopiperazine dimers; Marine fungi; Penicillium sp.; Verticillins

Indexed keywords

PIPERAZINEDIONE;

EID: 0344299039     PISSN: 10575634     EISSN: None     Source Type: Journal    
DOI: 10.1080/10575639908048788     Document Type: Article
Times cited : (71)

References (31)
  • 2
    • 0344363400 scopus 로고    scopus 로고
    • note
    • The fungal strain was identified as a Penicillium sp. based on fatty acid methyl ester analysis (Microbial ID, Inc. Newark, DE). Their analysis showed a similarity index of 0.85. indicating a good match with the genus Penicillium. No species assignment was achieved using FAME methods.
  • 3
    • 0344795155 scopus 로고    scopus 로고
    • note
    • The fungus was isolated as part of an expedition onboard the research vessel Seward Johnson in 1996, from the surface of the green alga Avrainvillea longicaulis collected at a depth of -5 m from a seagrass bed off Sweetings Cay, Grand Bahama Island, Bahamas. The producing strain was cultured for 17 days at 27°C in a medium composed of 0.5% yeast extract, 0.5% peptone, 1.0% glucose, 0.2% crab meal, and 100% seawater.
  • 4
    • 85088084438 scopus 로고    scopus 로고
    • note
    • 7 +703.7°).
  • 7
    • 0345226106 scopus 로고    scopus 로고
    • note
    • + m/z 665, m/z 491, 317, 271, 239, 179; LREIMS: m/z 256, 224, 192, 160, 128, 96, 64, 32. See Table 1 for NMR spectral data.
  • 19
    • 0344363398 scopus 로고    scopus 로고
    • note
    • + m/z 681; LREIMS: m/z 446, 384, 382, 256, 232, 224, 192, 168, 128, 96, 64, 32. See Table 2 for NMR spectral data.
  • 20
    • 0345657978 scopus 로고    scopus 로고
    • note
    • 4, dev 2.0 ppm.
  • 21
    • 0345657976 scopus 로고    scopus 로고
    • note
    • -1; UV(MeOH) 286 nm (ε 4600), 277 (ε 5200), 269(sh)(ε 5000), 215 (ε 34000); CD (MeOH) 242 nm (Δε -1.9), 223 (Δε +0.9), 212 (Δε -1.6); LREIMS: m/z 349, 301, 253, 155, 130. See Table 3 for NMR spectral data.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.