Studies on paraquat toxicity on deoxyribonucleic acid of cultured mammalian cells using flow cytometry

Redox Report

Volumn 2, Issue 1, 1996, Pages 19-24

  Tomita, M ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0344296274     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1080/13510002.1996.11747022     Document Type: Article

References (13)

1. Bus J S, Aust S D, Gibson J E. Superoxide and singlet oxygen catalyzed lipid peroxidation as a possible mechanism for paraquat toxicity. Biochem Biophys Res Commun 1974; 58: 749-755.
2. Bus J S, Aust S D, Gibson J E. Lipid peroxidation: a possible mechanism for paraquat toxicity. Res Commun Chem Pathol Pharmacol 1975; 11: 31-38.
3. Trush M A, Mimnaugh E G, Ginsburg E, Gram T E. In vitro stimulation by paraquat of reactive oxygen-mediated lipid peroxidation in rat lung microsomes. Toxicol Appl Pharmacol 1981; 60: 279-286.
4. Ilett K F, Stripp B, Menard R H, Reid W D, Gillette J R. Studies on the mechanism of the lung toxicity of paraquat: comparison of tissue distribution of some biochemical parameters in rats and rabbits. Toxicol Appl Pharmacol 1974; 28: 216-226.
5. Steffen C, Netter K J. On the mechanism of paraquat action on microsomal oxygen reduction and its relation to lipid peroxidation. Toxicol Appl Pharmacol 1979; 47: 593-602.
6. Scott M D, Meshnick S R, Eaton J W. Superoxide dismutase-rich bacteria. J Biol Chem 1987; 262: 3640-3645.
7. Bagley A C, Krall J, Lynch R E. Superoxide mediates the toxicity of paraquat for Chinese hamster ovary cells. Proc Natl Acad Sci USA 1986; 83: 3189-3193.
8. Krall J, Bagley A C, Mullenbach G T, Hallewell R A, Lynch R E. Superoxide mediates the toxicity of paraquat for cultured mammalian cells. J Biol Chem 1988; 263: 1910-1914.
9. Krall J, Speranza M J, Lynch R E. Paraquat-resistant HeLa cells: increased cellular content of glutathione peroxidase. Arch Biochem Biophys 1991; 286: 311-315.
10. Elroy-Stein O, Bernstein Y, Groner Y. Overproduction of human Cu/Zn-superoxide dismutase in transfected cells: extenuation of paraquat-mediated cytotoxicity and enhancement of lipid peroxidation. EMBO J 1986; 5: 615-622.
11. Peter B, Wartena M, Kampinga H H, Konings A W T. Role of lipid peroxidation and DNA damage in paraquat toxicity and the interaction of paraquat with ionizing radiation. Biochem Pharmacol 1992; 43: 705-715.
12. Walker L J, Craig R B, Harris A L, Hickson I D. A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress. Nucleic Acids Res 1944; 22: 4884-4889.
13. Buege J A, Aust S D. Microsomal lipid peroxidation. In: Fleischer S, Packer L, eds. Methods in Enzymology, vol. 52, New York: Academic Press, 1978: 302-310.