GABAB receptor activation and limbic network ictogenesis

Neuropharmacology

Volumn 46, Issue 1, 2004, Pages 43-51

  Avoli, Massimo ^a,b   Benini, Ruba ^a   De Guzman, Philip ^a   Omar, Amer ^a  

^a MCGILL UNIVERSITY   (Canada)

^b IRCCS NEUROMED   (Italy)

Author keywords

4 aminopyridine; Entorhinal cortex; GABAB receptors; Hippocampus; Ictogenesis; N methyl D aspartic acid receptors

Indexed keywords

3 AMINOPROPYL(DIETHOXYMETHYL)PHOSPHINIC ACID; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; 4 AMINOPYRIDINE; BACLOFEN; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ENTORHINAL CORTEX; EPILEPTIC DISCHARGE; HIPPOCAMPUS; IC 50; LIMBIC SYSTEM; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0344256518     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(03)00307-1     Document Type: Article

References (39)

1. Avoli M., Barbarosie M., Lucke A., Nagao T., Lopantsev V., Kohlig R. Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro. Journal of Neuroscience. 16:1996;3912-3924.
2. Avoli M., Louvel J., Kurcewicz I., Pumain R., Barbarosie M. Extracellular free potassium and calcium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus. Journal of Physiology. 493:1996;707-717.
3. Barbarosie M., Avoli M. CA3-driven hippocampal-entorhinal loop controls rather than sustains in vitro limbic seizures. Journal of Neuroscience. 17:1997;9308-9314.
4. Barbarosie M., Louvel J., Kurcewicz I., Avoli M. CA3-released entorhinal seizures disclose dentate gyrus epileptogenicity and unmask a temporoammonic pathway. Journal of Neurophysiology. 83:2000;1115-1124.
5. Bear J., Lothman E.W. An in vitro study of focal epileptogenesis in combined hippocampal-parahippocampal slices. Epilepsy Research. 14:1993;183-193.
6. Bowery N.G., Bettler B., Froestl W., Gallagher J.P., Marshall F., Raiteri M., Bonner T.I., Enna S.J. International union of pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function. Pharmacological Reviews. 54:2002;247-264.
7. 2+]. Brain Research. 590:1992;128-135.
8. D'Antuono M., Benini R., Biagini G., D'Arcangelo G., Barbarosie M., Tancredi V., Avoli M. Limbic network interactions leading to hyperexcitability in temporal lobe epilepsy. Journal of Neurophysiology. 87:2002;634-639.
9. de Curtis M., Avanzini G. Interictal spikes in focal epileptogenesis. Progress in Neurobiology. 63:2001;541-567.
10. Davies C.H., Starkey S.J., Pozza M.F., Collingridge G.L. GABA autoreceptors regulate the induction of LTP. Nature. 349:1991;609-611.
11. Deutch C., Spencer S., Robbins R., Cicchetti D., Spencer D. Interictal spikes and hippocampal somatostatin levels in temporal lobe epilepsy. Epilepsia. 32:1991;174-178.
12. 2+ induced epileptiform activityin rat temporal cortex slices. Experimental Brain Research. 87:1991;581-596.
13. Dudar P., Nicoll R.A. A physiological role for GABAB receptors in the central nervous system. Nature. 322:1988;156-158.
14. B receptors. Journal of Neuroscience. 16:1996;4250-4260.
15. Kofler M., Kronenberg M.F., Rifici C., Saltuari L., Bauer G. Epileptic seizures associated with intrathecal baclofen application. Neurology. 44:1994;25-27.
16. A receptor-mediated oscillations. Journal of Neuroscience. 20:2000;6820-6829.
17. Lewis D.V., Jonses L.S., Mott D.D. Baclofen induces spontaneous rhythmic sharp waves in the rat hippocampal slice. Experimental Neurology. 106:1989;181-186.
18. B-receptor-mediated processes in region CA1 in a chronic model of temporal lobe epilepsy. Journal of Neurophysiology. 76:1996;1282-1296.
19. Margeta-Mitrovic M., Mitrovic I., Riley R.C., Jan L.Y., Basbaum A.I. Immunohisto-chemical localization of GABA(B) receptors in the rat central nervous system. Journal of Comparative Neurology. 405:1999;299-321.
20. B receptors and the effects of baclofen in the mammalian central nervous system. Progress in Neurobiology. 46:1995;423-462.
21. Motalli R., Louvel J., Tancredi V., Kurcewicz I., Wan-Chow-Wah D., Pumain R., Avoli M. GABA(B) receptor activation promotes seizure activity in the juvenile rat hippocampus. Journal of Neurophysiology. 82:1999;638-647.
22. Motalli R., D'Antuono M., Louvel J., Kurcewicz I., D'Arcangelo G., Tancredi V., Manfredi M., Pumain R., Avoli M. Epileptiform synchronization and GABA(B) receptor antagonism in the juvenile rat hippocampus. Journal of Pharmacology and Experimental Therapeutics. 303:2002;1102-1113.
23. Mott D.D., Bragdon A.C., Lewis D.V., Wilson W.A. Baclofen has a proepileptic effect in the rat dentate gyrus. Journal of Pharmacology and Experimental Therapeutics. 249:1989;721-725.
24. Munoz A., Arellano J.I., DeFelipe J. GABABR1 receptor protein expression in human mesial temporal cortex: changes in temporal lobe epilepsy. Journal of Comparative Neurology. 449:2002;166-179.
25. Nagao T., Alonso A., Avoli M. Epileptiform activity induced by pilocarpine in the rat hippocampal-entorhinal slice preparation. Neuroscience. 72:1996;399-408.
26. Paré D., de Curtis M., Llinás R. Role of hippocampal-entorhinal loop in temporal lobe epilepsy: extra- and intracellular study in the isolated guinea pig brain in vitro. Journal of Neuroscience. 12:1992;1857-1881.
27. Princivalle A.P., Duncan J.S., Thom M., Bowery N.G. Studies of GABA(B) receptors labelled with [(3)H]-CGP62349 in hippocampus resected from patients with temporal lobe epilepsy. British Journal of Pharmacology. 136:2002;1099-1106.
28. Prosser H.M., Gill C.H., Hirst W.D., Grau E., Robbins M., Calver A., Soffin E.M., Farmer C.E., Lanneau C., Gray J., Schenck E., Warmerdam B.S., Clapham C., Reavill C., Rogers D.C., Stean T., Upton N., Humphreys K., Randall A., Geppert M., Davies C.H., Pangalos M.N. Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice. Molecular and Cellular Neuroscience. 17:2001;1059-1070.
29. Rush J.M., Gibberd F.B. Baclofen-induced epilepsy. Journal of the Royal Society of Medicine. 83:1990;115-116.
30. Rutecki P.A., Grossman R.G., Armstrong D., Irish-Loewen S.J. Electrophysiological connections between the hippocampus and entorhinal cortex in patients with complex partial seizures. Journal of Neurosurgery. 70:1989;667-675.
31. Schuler V., Luscher C., Blanchet C., Klix N., Sansig G., Klebs K., Schmutz M., Heid J., Gentry C., Urban L., Fox A., Spooren W., Jaton A.L., Vigouret J., Pozza M., Kelly P.H., Mosbacher J., Froestl W., Kaslin E., Korn R., Bischoff S., Kaupmann K., van der Putten H., Bettler B. Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)). Neuron. 31:2001;47-58.
32. Spencer S.S., Spencer D.D. Entorhinal-hippocampal interactions in temporal lobe epilepsy. Epilepsia. 35:1994;721-727.
33. B receptors in convulsant-induced epileptiform activity in rat neocortex in vitro. European Journal of Neuroscience. 10:1998;3417-3427.
34. Swartzwelder H.S., Lewis D.V., Anderson W.W., Wilson W.A. Seizure-like events in brain slices: suppression by interictal activity. Brain Research. 410:1987;362-366.
35. Thompson S.M., Gähwiler B.H. Comparison of the actions of baclofen at pre- and post-synaptic receptors in the rat hippocampus in vitro. Journal of Physiology (London). 451:1992;329-345.
36. Traub R.D., Borck C., Collins S.B., Jefferys J.G. On the structure of ictal events in vitro. Epilepsia. 37:1996;879-891.
37. Uusisaari M., Smirnov S., Voipio J., Kaila K. Spontaneous epileptiform activity mediated by GABA(A) receptors and gap junctions in the rat hippocampal slice following long-term exposure to GABA(B) antagonists. Neuropharmacology. 43:2002;563-572.
38. Watts A.E., Jefferys J.G.R. Effects of carbamazepine and baclofen on 4-aminopyridine-induced epileptic activity in rat hippocampal slices. British Journal of Pharmacology. 108:1993;819-823.
39. Wilson W.A., Swartzwelder H.S., Anderson W.W., Lewis D.V. Seizure activity in vitro: a dual focus model. Epilepsy Research. 2:1988;289-293.