Neuronal nicotinic acetylcholine receptors: Their properties and alterations in autosomal dominant nocturnal frontal lobe epilepsy

Revue Neurologique

Volumn 155, Issue 6-7, 1999, Pages 457-462

  Bertrand, D ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; DIZOCILPINE; NICOTINIC RECEPTOR;

ARTICLE; AUTOSOMAL DOMINANT DISORDER; BINDING AFFINITY; BINDING SITE; BRAIN DYSFUNCTION; FRONTAL LOBE EPILEPSY; GENE MUTATION; GENETIC LINKAGE; HUMAN; NONHUMAN; RECEPTOR BINDING; RECEPTOR BLOCKING; SEIZURE;

EPILEPSY, FRONTAL LOBE; GENES, DOMINANT; HOMOZYGOTE; HUMANS; MUTATION; NEURONS; RECEPTORS, NICOTINIC;

EID: 0344246904     PISSN: 00353787     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. ALBUQUERQUE E.X., PEREIRA E., ALKONDON M., SCHRATTENHOLZ A., MAELICKE A. (1997) Minireview: Nicotinic acetylcholine receptors on hippocampal neurons: Distribution on the neuronal surface and modulation of receptor activity. J Receptor Signal Transduction Research 17: 243-266.
2. ASCHER P., LARGE W.A., RANG H.P. (1979) Studies on the mechanism of action of acetylcholine antagonists on rat parasympathetic ganglion cells. Journal. Physiology 295: 139-170.
3. BERTRAND D, CHANGEUX J.P. (1995) Nicotinic receptor: An allosteric protein specialized for intercellular communication. Sem Neuroscience 7: 75-90.
4. BERTRAND D., COOPER E., VALERA S., RUNGGER D., BALLIVET M. (1991) Electrophysiology of neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes following nuclear injection of genes or cDNA. New York: Academic Press.
5. BUISSON B., BERTRAND D. (1998) Open-channel blockers at the human α4β2 neuronal nicotinic acetylcholine receptor. Molecular Pharmacology 53: 555-563.
6. BUISSON B., GOPALAKRISHNAN M., ARNERIC S.P., SULLIVAN J.P., BERTRAND D. (1996) Human α4β2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study. J Neuroscience 16: 7880-7891.
7. CHANGEUX J.P. (1990). Functional architecture and dynamics of the nicotinic acetylcholine receptor: an allosteric ligand-gated ion channel. In Changeux JP, Llinàs RR, Purves D, Bloom FE (eds). Fidia Research Foundation Neuroscience Award Lectures, pp. 21-168. Raven Press Ltd, New York.
8. EPPING-JORDAN M.P., WATKINS S.S., KOOB G.F., MARKOU A. (1998) Dramatic decreases in brain reward function during nicotine withdrawal. Nature 393: 76-79.
9. GALZI J.L., CHANGEUX J.P. (1995) Neuronal nicotinic receptors: Molecular organization and regulations. Neuropharmacology 34: 563-582.
10. GOPALAKRISHNAN M., MONTEGGIA L.M., ANDERSON D.J., MOLINARI E.J., PIATTONI-KAPLAN M., DONNELLY-ROBERTS D., ARNERIC S.P., SULLIVAN J.P. (1996) Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor. J Pharmacol Exp Ther 276: 289-97.
11. GRAY R., RAJAN A.S., RADCLIFFE K.A., YAKEHIRO M., DANI J.A. (1996) Hippocampal synaptic transmission enhanced by low concentrations of nicotine. Nature 383: 713-716.
12. KURYATOV A., GERZANICH V., NELSON M., OLALE F., LINDSTROM J. (1997) Mutation causing autosomal dominant nocturnal frontal lobe epilepsy alters Ca2+ permeability, conductance, and gating of human alpha 4 beta 2 nicotinic acetylcholine receptors. J Neuroscience 17: 9035-9047.
13. 2+ ions in nicotinic facilitation of GABA release in mouse thalamus. J Neuroscience 17: 576-585.
14. LINDSTROM J. (1997) Nicotinic acetylcholine receptors in health and disease. Molecular Neurobiology 15: 193-222.
15. LINDSTROM J., ANAND R., PENG X., GERZANICH V., WANG F., LI Y. (1995) Neuronal nicotinic receptor subtypes. Ann N Y Acad Sci 757: 100-16.
16. MCGEHEE D.S., ROLE L.W. (1996) Presynaptic ionotropic receptors. Current Opinion Neurobiology 6: 342-349.
17. NEWHOUSE P.A., POTTER A., LEVIN E.D. (1997) Nicotinic system involvement in Alzheimer's and Parkinson's diseases: Implications for therapeutics. Drug Aging 11: 206-228.
18. PHILLIPS H.A., MULLEY J.C. (1997) SSCP variants within the alpha 4 subunit of the neuronal nicotinic acetylcholine receptor gene. Clinical Genetic 51: 135-136.
19. PICARD F., BERTRAND S., STEINLEIN O.K., BERTRAND D. Human neuronal nicotinic acetylcholine receptors are highly sensitive to the antiepileptic drug carbamazepine. Epilepsia Submitted:
20. PICCIOTTO M.R., ZOLI M., RIMONDINI R., LENA C., MARUBIO L.M., PICH E.M., FUXE K., CHANGEUX J.P. (1998) Acetylcholine receptors containing the beta 2 subunit are involved in the reinforcing properties of nicotine. Nature 391: 173-177.
21. PICCIOTTO M.R., ZOLI M., ZACHARIOU V., CHANGEUX J.P. (1997) Contribution of nicotinic acetylcholine receptors containing the beta 2-subunit to the behavioural effects of nicotine. Biochemical Society Transaction 25: 824-829.
22. RUBBOLI F., COURT J.A., SALA C., MORRIS C., PERRY E., CLEMENTI F. (1994) Distribution of neuronal nicotinic receptor subunits in human brain. Neurochemistry International 25: 69-71.
23. SCHRODER H., GIACOBINI E., WEVERS A., BIRTSCH A., SCHUTZ U. Nicotinic receptors in Alzheimer's disease. P O Box 1491/Ann Arbor/MI 48106: Npp Books, 1995.
24. STEINLEIN O.K., MAGNUSSON A., STOODT J., BERTRAND S., WEILAND S., BERKOVIC S.F., NAKKEN K.O., PROPPING P., BERTRAND D. (1997) An insertion mutation of the CHRNA4 gene in a family with autosomal dominant nocturnal frontal lobe epilepsy. Human Molecular Genetic 6: 943-947.
25. STEINLEIN O.K., MULLEY J.C., PROPPING P., WALLACE R.H., PHILLIPS H.A., SUTHERLAND G.R., SCHEFFER I.E., BERKOVIC S.F. (1995) A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy. Nature Genetic 11: 201-3.
26. SVENSSON A.L., WARPMAN U., HELLSTROMLINDAHL E., BOGDANOVIC N., LANNFELT L., NORDBERG A. (1997) Nicotinic receptors, muscarinic receptors and choline acetyltransferase activity in the temporal cortex of Alzheimer patients with differing apolipoprotein E genotypes. Neuroscience Letter 232: 37-40.
27. WADA E., WADA K., BOULTER J., DENERIS E., HEINEMANN S., PATRICK J., SWANSON L.W. (1989) Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat. J Comparative Neurology 284: 314-335.
28. WARPMAN U., NORDBERG A. (1995) Epibatidine and ABT 418 reveal selective losses of alpha 4 beta 2 nicotinic receptors in Alzheimer brains. Neuroreport 6: 2419-2423.
29. WEILAND S., WITZEMANN V., VILLARROEL A., PROPPING P., STEINLEIN O. (1996) An amino acid exchange in the second transmembrane segment of a neuronal nicotinic receptor causes partial epilepsy by altering its desensitization kinetics. FEBS Letter 398: 91-6.
30. ZOLI M., LE NOVÈRE N., HILL J.A., Jr., CHANGEUX J.P. (1995) Developmental regulation of nicotinic Ach receptor subunit mRNAs in the rat central and peripheral nervous systems. J Neuroscience 15: 1912-1939.