Pharmacokinetic/pharmacodynamic modeling of luteinizing hormone (LH) suppression and LH surge delay by cetrorelix after single and multiple doses in healthy premenopausal women

Journal of Clinical Pharmacology

Volumn 43, Issue 3, 2003, Pages 243-251

  Nagaraja V, Nelamangala ^a   Pechstein, Birgit ^b   Erb, Katharina ^c   Klipping, Christine ^d   Hermann, Robert ^b   Locher, Mathias ^b   Derendorf, Hartmut ^a  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

^b Viatris Inc   (Germany)

^c Clinphase Clinical Pharmacology Services   (Germany)

^d Medical Investigations   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CETRORELIX; GONADORELIN ANTAGONIST; LUTEINIZING HORMONE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG HALF LIFE; FEMALE; FERTILIZATION IN VITRO; HORMONE SYNTHESIS; HUMAN; HUMAN EXPERIMENT; LUTEINIZING HORMONE RELEASE; MAXIMUM ALLOWABLE CONCENTRATION; MENSTRUAL CYCLE; NORMAL HUMAN; OVARY FUNCTION; OVULATION; PHARMACODYNAMICS; PREMENOPAUSE;

ADOLESCENT; ADULT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ESTRADIOL; FEMALE; FOLLICLE STIMULATING HORMONE; GONADOTROPIN-RELEASING HORMONE; HALF-LIFE; HORMONE ANTAGONISTS; HUMANS; INJECTIONS, SUBCUTANEOUS; LUTEINIZING HORMONE; OVULATION; PREMENOPAUSE; PROGESTERONE; TIME FACTORS;

EID: 0344211862     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/0091270003251377     Document Type: Article

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