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Volumn 54, Issue 10, 1999, Pages 653-659

Theoretical study of mexiletine and its interaction with cationic and anionic receptor sites

Author keywords

Antiarrhythmic receptor interaction; Mexiletine; Theoretical calculations

Indexed keywords

AMINE; ANION; CATION; MEMBRANE PROTEIN; MEXILETINE;

EID: 0344199931     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(99)00074-9     Document Type: Article
Times cited : (5)

References (32)
  • 1
    • 0022345664 scopus 로고
    • Antiarrhythmic drug therapy
    • Somberg J. Antiarrhythmic drug therapy. Cardiology. 72:1985;329-348.
    • (1985) Cardiology , vol.72 , pp. 329-348
    • Somberg, J.1
  • 3
    • 0025857263 scopus 로고
    • Antiarrhythmic drug classifications. A critical appraisal of their history, present status and clinical relevance
    • Nattel S. Antiarrhythmic drug classifications. A critical appraisal of their history, present status and clinical relevance. Drugs. 41:1991;672-701.
    • (1991) Drugs , vol.41 , pp. 672-701
    • Nattel, S.1
  • 4
    • 0025822969 scopus 로고
    • Molecular action of class I antiarrhythmic drugs and clinical implications
    • Kecskemeti V. Molecular action of class I antiarrhythmic drugs and clinical implications. Pharmacol. Res. 24:1991;131-142.
    • (1991) Pharmacol. Res. , vol.24 , pp. 131-142
    • Kecskemeti, V.1
  • 5
    • 0031857508 scopus 로고    scopus 로고
    • Clinical pharmacology of antiarrhythmic drugs
    • Capucci A., Aschieri D., Villani G.Q. Clinical pharmacology of antiarrhythmic drugs. Drugs Aging. 13:1998;51-70.
    • (1998) Drugs Aging , vol.13 , pp. 51-70
    • Capucci, A.1    Aschieri, D.2    Villani, G.Q.3
  • 7
    • 0021717174 scopus 로고
    • Antiarrhythmic drug action: Blockade of the inward sodium current
    • Grant A.O., Starmer C.F., Strauss H.C. Antiarrhythmic drug action: blockade of the inward sodium current. Circ. Res. 55:1984;427-439.
    • (1984) Circ. Res. , vol.55 , pp. 427-439
    • Grant, A.O.1    Starmer, C.F.2    Strauss, H.C.3
  • 9
    • 0017332486 scopus 로고
    • Local anesthetics: Hydrophilic and hydrophobic pathways for the drug-receptor reaction
    • Hille B. Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction. J. Gen. Physiol. 69:1977;497-515.
    • (1977) J. Gen. Physiol. , vol.69 , pp. 497-515
    • Hille, B.1
  • 10
    • 0026718289 scopus 로고
    • Block and modulation of cardiac sodium channels by antiarrhythmic drugs, neurotransmitters and hormones
    • Grant A.O, Wendt D.J. Block and modulation of cardiac sodium channels by antiarrhythmic drugs, neurotransmitters and hormones. Trends Pharmacol. Sci. 13:1992;352-358.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 352-358
    • Grant, A.O.1    Wendt, D.J.2
  • 11
    • 0025778179 scopus 로고
    • Ab initio investigation of interactions between models of membrane-active compounds and polar groups of membranes: Complexes involving amine, ether, amide, phosphate, and carboxylate
    • Remko M., Scheiner S. Ab initio investigation of interactions between models of membrane-active compounds and polar groups of membranes: complexes involving amine, ether, amide, phosphate, and carboxylate. J. Pharm. Sci. 80:1991;328-332.
    • (1991) J. Pharm. Sci. , vol.80 , pp. 328-332
    • Remko, M.1    Scheiner, S.2
  • 12
    • 0000203720 scopus 로고
    • Effects of external ions on the energetics of proton transfer in hydrogen bonded systems modelling a membrane-active drug-receptor interaction
    • Remko M., Rode B.M. Effects of external ions on the energetics of proton transfer in hydrogen bonded systems modelling a membrane-active drug-receptor interaction. J. Chem. Soc., Faraday Trans. 89:1993;1321-1326.
    • (1993) J. Chem. Soc., Faraday Trans. , vol.89 , pp. 1321-1326
    • Remko, M.1    Rode, B.M.2
  • 13
    • 0002430426 scopus 로고
    • Molecular modelling of the antiarrhythmic-receptor interaction
    • Remko M., Scheiner S., Rode B.M. Molecular modelling of the antiarrhythmic-receptor interaction. J. Mol. Struct.: Theochem. 307:1994;35-46.
    • (1994) J. Mol. Struct.: Theochem. , vol.307 , pp. 35-46
    • Remko, M.1    Scheiner, S.2    Rode, B.M.3
  • 15
    • 0033215136 scopus 로고    scopus 로고
    • Cation binding effect on hydrogen bonding in the complexes of lidocaine, tocainide and mexiletine with the acetate
    • in press
    • M. Remko, B.M. Rode, Cation binding effect on hydrogen bonding in the complexes of lidocaine, tocainide and mexiletine with the acetate, J. Mol. Struct.: Theochem. (1999) in press.
    • (1999) J. Mol. Struct.: Theochem.
    • Remko, M.1    Rode, B.M.2
  • 16
    • 0033009033 scopus 로고    scopus 로고
    • The interaction of antiarrhythmics with an anionic receptor site
    • Remko M. The interaction of antiarrhythmics with an anionic receptor site. IDrugs. 2:1999;243-246.
    • (1999) IDrugs , vol.2 , pp. 243-246
    • Remko, M.1
  • 17
    • 0003669619 scopus 로고    scopus 로고
    • Hypercube Inc., 1115 NW 4th Street, Gainesville, FL 32601-4256, USA
    • HYPERCHEM, version 5.02, Hypercube Inc., 1115 NW 4th Street, Gainesville, FL 32601-4256, USA, 1998.
    • (1998) HYPERCHEM, Version 5.02
  • 18
    • 0028861514 scopus 로고
    • MOLGEN: Personal computer-based modeling system
    • Baricic P., Mackov M. MOLGEN: personal computer-based modeling system. J. Mol. Graph. 13:1995;184-189.
    • (1995) J. Mol. Graph. , vol.13 , pp. 184-189
    • Baricic, P.1    Mackov, M.2
  • 19
    • 0344854305 scopus 로고    scopus 로고
    • Chemical Design Ltd., Chipping Norton, OX7 5SR, UK
    • CHEM-X, Chemical Design Ltd., Chipping Norton, OX7 5SR, UK, 1998.
    • (1998) CHEM-X
  • 20
    • 2442617487 scopus 로고
    • Self-consistent molecular orbital methods 21. Small split-valence basis sets for first-row elements
    • Binkley J.S., Pople J.A., Hehre W.J. Self-consistent molecular orbital methods 21. Small split-valence basis sets for first-row elements. J. Am. Chem. Soc. 102:1980;939-947.
    • (1980) J. Am. Chem. Soc. , vol.102 , pp. 939-947
    • Binkley, J.S.1    Pople, J.A.2    Hehre, W.J.3
  • 21
    • 0345013459 scopus 로고
    • Structure of 1-(2,6-dimethylphenoxy)-2-propanamine hydrochloride
    • Sivý J., Kettmann V., Frešová E. Structure of 1-(2,6-dimethylphenoxy)-2-propanamine hydrochloride. Acta Crystallogr., Sect. C. 47:1991;2695-2696.
    • (1991) Acta Crystallogr., Sect. C , vol.47 , pp. 2695-2696
    • Sivý, J.1    Kettmann, V.2    Frešová, E.3
  • 22
    • 0031521482 scopus 로고    scopus 로고
    • Theoretical study of the local anaesthetic-receptor interaction
    • Remko M., Liedl K.R., Rode B.M. Theoretical study of the local anaesthetic-receptor interaction. Chem. Papers. 51:1997;234-241.
    • (1997) Chem. Papers , vol.51 , pp. 234-241
    • Remko, M.1    Liedl, K.R.2    Rode, B.M.3
  • 23
    • 84890021933 scopus 로고
    • The calculation of small molecular interactions by the differences of separate total energies. Some procedures with reduced errors
    • Boys S.F., Bernardi F. The calculation of small molecular interactions by the differences of separate total energies. Some procedures with reduced errors. Mol. Phys. 19:1970;553-566.
    • (1970) Mol. Phys. , vol.19 , pp. 553-566
    • Boys, S.F.1    Bernardi, F.2
  • 25
    • 0029610054 scopus 로고
    • Relative potency of mexiletine, lidocaine, and tocainide as inhibitors of rat liver CYP1A1 activity
    • Wei X., Loi Ch.M., Jarvi E.J., Vestal R.E. Relative potency of mexiletine, lidocaine, and tocainide as inhibitors of rat liver CYP1A1 activity. Drug Metab. Dispos. 23:1995;1335-1338.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 1335-1338
    • Wei, X.1    Loi, Ch.M.2    Jarvi, E.J.3    Vestal, R.E.4
  • 26
    • 0028844521 scopus 로고
    • Stereoselective effects of mexiletine enantiomers on sodium currents and excitability characteristics of adult skeletal muscle fibers
    • Deluca A., Natuzzi F., Lentini G., Franchini C., Tortorella V., Camerino D.C. Stereoselective effects of mexiletine enantiomers on sodium currents and excitability characteristics of adult skeletal muscle fibers. Naunyn Schmiedebergs Arch. Pharm. 352:1995;653-661.
    • (1995) Naunyn Schmiedebergs Arch. Pharm. , vol.352 , pp. 653-661
    • Deluca, A.1    Natuzzi, F.2    Lentini, G.3    Franchini, C.4    Tortorella, V.5    Camerino, D.C.6
  • 28
    • 0024262760 scopus 로고
    • Interactions of antiarrhythmics with artificial phospholipid membranes
    • Voigt W., Mannhold R., Limberg J., Blaschke G. Interactions of antiarrhythmics with artificial phospholipid membranes. J. Pharm. Sci. 77:1988;1018-1020.
    • (1988) J. Pharm. Sci. , vol.77 , pp. 1018-1020
    • Voigt, W.1    Mannhold, R.2    Limberg, J.3    Blaschke, G.4
  • 29
    • 0024280869 scopus 로고
    • Structure and function of voltage-sensitive ion channels
    • Catterall W.A. Structure and function of voltage-sensitive ion channels. Science. 242:1988;50-61.
    • (1988) Science , vol.242 , pp. 50-61
    • Catterall, W.A.1
  • 30
    • 0542382495 scopus 로고
    • Solvent effects. 1. The mediation of electrostatic effects by solvents
    • Wong M.W., Frisch M.J., Wiberg K.B. Solvent effects. 1. The mediation of electrostatic effects by solvents. J. Am. Chem. Soc. 113:1991;4776-4782.
    • (1991) J. Am. Chem. Soc. , vol.113 , pp. 4776-4782
    • Wong, M.W.1    Frisch, M.J.2    Wiberg, K.B.3
  • 31
    • 7044239742 scopus 로고
    • Free energy calculations: Applications to chemical and biochemical phenomena
    • Kollman P. Free energy calculations: applications to chemical and biochemical phenomena. Chem. Rev. 93:1993;2395-2417.
    • (1993) Chem. Rev. , vol.93 , pp. 2395-2417
    • Kollman, P.1
  • 32
    • 0029623184 scopus 로고
    • Computational methods to predict binding free energy in ligand-receptor complexes
    • Jain A.N., Murcko M.A. Computational methods to predict binding free energy in ligand-receptor complexes. J. Med. Chem. 38:1995;4953-4967.
    • (1995) J. Med. Chem. , vol.38 , pp. 4953-4967
    • Jain, A.N.1    Murcko, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.