5-Hydroxylapachol: A cytotoxic agent from Tectona grandis

Phytochemistry

Volumn 50, Issue 3, 1998, Pages 439-442

  Khan, Rafiullah M ^a   Mlungwana, Suleiman M ^b  

^a PAPUA NEW GUINEA UNIVERSITY OF TECHNOLOGY   (Papua New Guinea)

^b UNIVERSITY OF DAR ES SALAAM   (Tanzania)

Author keywords

5 Hydroxylapachol; Cytotoxicity; Dehydro lapachone; Lapachol; Methylquinizarin; Naphthoquinones; Squalene; Tectona grandis; Verbenaceae

Indexed keywords

5 HYDROXYLAPACHOL; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; DEHYDROLAPACHONE; LAPACHOL; METHYLQUINIZARIN; SQUALENE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTEMIA; ARTICLE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; NONHUMAN; PLANT; PROTON NUCLEAR MAGNETIC RESONANCE; TECTONA GRANDIS;

ARTEMIA SALINA; TECTONA GRANDIS;

EID: 0344197542     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(98)00478-6     Document Type: Article

References (22)

1. Almeida, E. R. D., Filho, A. A. D. S., Santos, E. R. D., & Lopes, C. A. C. (1990). J. Ethnopharmacol., 29, 239.
2. Burnett, A. R. and Thomson, R. H., J. Chem. Soc. C, 1968, 850-853.
3. Cannon, J. K., Joshi, K. R. and McDonald, I. A., Tetrahedron Lett., 1975, 2795-5.
4. Doganca, S., Gurkan, E., Hirlak, F., Tuzun, O. T., & Tuzlaci, E. (1997). Fitoterapia, LXVIII, 80.
5. Gafner, S., Wolfender, J. L., Nianga, M., Stoeckli-Evans, H., & Hostettmann, K. (1996). Phytochemistry, 42, 1315.
6. Goncalves de Lima, O., D'Albuquerque, I. L., Goncalves de Lima, C., & Dalia Maria, M. H. (1962). Rev. Inst. Antibiot. (Recife), 4, 3.
7. Guiraud, P., Steiman, R., Campos-Takaki, G. M., Seigle-Murandi, F., & Simeon de Bouchberg, M. (1964). Planta Med., 60, 373.
8. Johnson, L. F., & Jankowski, W. C. (1972). Carbon-13 NMR spectra. New York: John Wiley and Sons.
9. Kopanski, L., Li, G. R., Best, H., & Steglich, W. (1982). Liebigs Ann. Chem., 1722.
10. Lillie, T. J., Musgrave, O. C., & Skoyles, D. (1977). J.C.S. Perkin Trans. I, 355.
11. Matsumoto, T., Ichihara, A., Yanagiya, M., Yuzawa, T., Sannai, A., Oikawa, H., Sakamura, S., & Eugster, C. H. (1985). Helv. Chim. Acta, 68, 2324.
12. Meyer, B. N., Ferrigni, N. R., Putnam, J. E., Jacobsen, L. B., & Nichols, D. E. (1982). Planta Med., 45, 31.
13. Pouchart, C. (1983). The Aldrich library of NMR spectra (2nd ed.) (p. 36c). Aldrich.
14. Rameshwar, J., & Seshadri, T. R. (1979). J. Indian Chem. Soc., 56, 940-941.
15. Rao, K. V. (1974). Cancer Chemother. Rep., 4 (Part 2), 11.
16. Rao, M. M., & Kingston, D. G. I. (1982). J. Nat. Prod., 45, 600.
17. Rao, K. V., McBride, T. J., & Oleson, J. J. (1968a). Cancer Res., 28, 1952.
18. Rao, K. V., McBride, T. J., & Oleson, J. J. (1968b). Cancer Res., 28, 1952.
19. Santana, C. F., Lins, L. J. P., Asfora, J. J., Melo, A. M., Lima, G., & D'Albuquerque, I. L. (1980-1981). Rev. Inst. Antibiot., 20, 61.
20. Silverstein, R. M., Bassler, G. C., & Morrill, T. C. (1981). Spectroscopic identification of organic compounds (4th ed.). New York, Chichester, Brisbane, Toronto: John Wiley and Sons.
21. Singh, P., Jain, S., & Bhargara, S. (1989). Phytochemistry, 28, 1258-1289.
22. Thomson, R. H. (1971). Naturally occurring quinones (2nd ed.) London and New York: Academic Press.