Improved liquid chromatographic method for mitoxantrone quantification in mouse plasma and tissues to study the pharmacokinetics of a liposome entrapped mitoxantrone formulation

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 799, Issue 1, 2004, Pages 149-155

  Johnson, Jenifer L ^a   Ahmad, Ateeq ^a   Khan, Sumsullah ^a   Wang, Yue Fen ^a   Abu Qare, Aqel W ^a   Ayoub, Jennifer E ^a   Zhang, Allen ^a   Ahmad, Imran ^a  

^a NeoPharm Inc   (United States)

Author keywords

Mitoxantrone; Pharmacokinetics

Indexed keywords

ABSORPTION; BODY FLUIDS; HYDROCHLORIC ACID; METHANOL; PRECIPITATION (CHEMICAL); PROTEINS; TISSUE;

PHARMACOKINETIC STUDY;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ACETONITRILE; AMETANTRONE; HYDROCHLORIC ACID; LIPOSOME; METHANOL; MITOXANTRONE;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG FORMULATION; DRUG TISSUE LEVEL; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY PARENCHYMA; LIVER; MALE; MOUSE; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SAMPLE; SEPARATION TECHNIQUE; SPLEEN; STANDARD; TISSUE HOMOGENATE;

EID: 0344196913     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2003.10.034     Document Type: Article

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