Diarylsemicarbazones: Synthesis, antineoplastic activity and topoisomerase I inhibition assay

Farmaco

Volumn 54, Issue 8, 1999, Pages 517-523

  Asís, Silvia E ^a   Bruno, Ana M ^a   Martínez, Andrea R ^a   Sevilla, María V ^a   Gaozza, Carlos H ^a   Romano, Alejandra M ^b   Coussio, Jorge D ^b   Ciccia, Graciela ^b  

^a Depto Bioquim Clin Fac F   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Antineoplastic activity; Diarylsemicarbazones; Synthesis; Topoisomerase I inhibition

Indexed keywords

DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; SEMICARBAZONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOSTASIS; DNA BINDING; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPOPHILICITY; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; AZO COMPOUNDS; DNA; DNA TOPOISOMERASES, TYPE I; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTROCHEMISTRY; ENZYME INHIBITORS; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0344172799     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(99)00050-6     Document Type: Article

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