메뉴 건너뛰기




Volumn 338, Issue 1-2, 2003, Pages 157-164

Moderate hyperhomocysteinaemia and immune activation in patients with rheumatoid arthritis

Author keywords

Homocysteine; Immune activation; Neopterin; Oxidative stress; Rheumatoid arthritis; Vitamin deficiency

Indexed keywords

AZATHIOPRINE; CYANOCOBALAMIN; CYCLOSPORIN A; CYSTEINE; DICLOFENAC; FOLIC ACID; HOMOCYSTEINE; IBUPROFEN; IMMUNOSUPPRESSIVE AGENT; LOMOXICAM; MELOXICAM; METHOTREXATE; NEOPTERIN; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; SALAZOSULFAPYRIDINE; TRAMADOL; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VITAMIN B GROUP;

EID: 0344154549     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cccn.2003.09.003     Document Type: Article
Times cited : (60)

References (37)
  • 1
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
    • Boushey C.J., Beresford S.A., Omenn G.S., Motulsky A.G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA. 274:1995;1049-1057.
    • (1995) JAMA , vol.274 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 2
    • 0031944655 scopus 로고    scopus 로고
    • Serum homocysteine and methylmalonic acid in patients with rheumatoid arthritis and cobalaminopenia
    • Pettersson T., Friman C., Abrahamsson L., Nilsson B., Norberg B. Serum homocysteine and methylmalonic acid in patients with rheumatoid arthritis and cobalaminopenia. J. Rheumatol. 25:1998;859-863.
    • (1998) J. Rheumatol. , vol.25 , pp. 859-863
    • Pettersson, T.1    Friman, C.2    Abrahamsson, L.3    Nilsson, B.4    Norberg, B.5
  • 3
    • 0030966942 scopus 로고    scopus 로고
    • Abnormal homocysteine metabolism in rheumatoid arthritis
    • Roubenoff R., Dellaripa P., Nadeau M.R.et al. Abnormal homocysteine metabolism in rheumatoid arthritis. Arthritis Rheum. 40:1997;718-722.
    • (1997) Arthritis Rheum. , vol.40 , pp. 718-722
    • Roubenoff, R.1    Dellaripa, P.2    Nadeau, M.R.3
  • 4
    • 0034943763 scopus 로고    scopus 로고
    • Hyperhomocysteinaemia in Behcet's disease
    • Aksu K., Turgan N., Oksel F.et al. Hyperhomocysteinaemia in Behcet's disease. Rheumatology. 40:2001;687-690.
    • (2001) Rheumatology , vol.40 , pp. 687-690
    • Aksu, K.1    Turgan, N.2    Oksel, F.3
  • 5
    • 0033728995 scopus 로고    scopus 로고
    • Homocysteine concentration in primary and systemic sclerosis associated Raynaud's phenomenon
    • Marasini B., Casari S., Bestetti A.et al. Homocysteine concentration in primary and systemic sclerosis associated Raynaud's phenomenon. J. Rheumatol. 27:2000;2621-2623.
    • (2000) J. Rheumatol. , vol.27 , pp. 2621-2623
    • Marasini, B.1    Casari, S.2    Bestetti, A.3
  • 6
    • 0034769809 scopus 로고    scopus 로고
    • Changes in plasma homocysteine in arthritis patients starting treatment with low-dose methotrexate subsequently supplemented with folic acid
    • Slot O. Changes in plasma homocysteine in arthritis patients starting treatment with low-dose methotrexate subsequently supplemented with folic acid. Scand. J. Rheumatol. 30:2001;305-307.
    • (2001) Scand. J. Rheumatol. , vol.30 , pp. 305-307
    • Slot, O.1
  • 7
    • 0022970777 scopus 로고
    • The effect of methothrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis
    • Allegra C.J., Fine R.L., Drake J.C., Chabner B.A. The effect of methothrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis. J. Biol. Chem. 261:1986;6478-6485.
    • (1986) J. Biol. Chem. , vol.261 , pp. 6478-6485
    • Allegra, C.J.1    Fine, R.L.2    Drake, J.C.3    Chabner, B.A.4
  • 8
    • 0034946608 scopus 로고    scopus 로고
    • Homocysteine modulation as a reason for continuous folic acid supplementation in methotrexate-treated rheumatoid arthritis patients
    • Erb N., Kitas G.D. Homocysteine modulation as a reason for continuous folic acid supplementation in methotrexate-treated rheumatoid arthritis patients. Rheumatology. 40:2001;715-716.
    • (2001) Rheumatology , vol.40 , pp. 715-716
    • Erb, N.1    Kitas, G.D.2
  • 9
    • 0031936472 scopus 로고    scopus 로고
    • Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during long-term, low dose methotrexate therapy for rheumatoid arthritis: Implications for cardiovascular disease prevention
    • Morgan S.L., Baggott J.E., Lee J.Y., Alarcon G.S. Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during long-term, low dose methotrexate therapy for rheumatoid arthritis: implications for cardiovascular disease prevention. J. Rheumatol. 25:1998;441-446.
    • (1998) J. Rheumatol. , vol.25 , pp. 441-446
    • Morgan, S.L.1    Baggott, J.E.2    Lee, J.Y.3    Alarcon, G.S.4
  • 10
    • 0034820518 scopus 로고    scopus 로고
    • Homocysteine and antiphospholipid antibodies in rheumatoid arthritis patients: Relationships with thrombotic events
    • Seriolo B., Fasciolo D., Sulli A., Cutolo M. Homocysteine and antiphospholipid antibodies in rheumatoid arthritis patients: relationships with thrombotic events. Clin. Exp. Rheumatol. 19:2001;561-564.
    • (2001) Clin. Exp. Rheumatol. , vol.19 , pp. 561-564
    • Seriolo, B.1    Fasciolo, D.2    Sulli, A.3    Cutolo, M.4
  • 11
    • 0001978378 scopus 로고
    • Rheumatoid arthritis: Epidemiology, pathology and pathogenesis
    • H.R. Schumacher. Atlanta: Arthritis Foundation
    • Wilder R.L. Rheumatoid arthritis: epidemiology, pathology and pathogenesis. Schumacher H.R. Primer on Rheumatic Diseases. 1993;86-89 Arthritis Foundation, Atlanta.
    • (1993) Primer on Rheumatic Diseases , pp. 86-89
    • Wilder, R.L.1
  • 12
    • 0026806992 scopus 로고
    • Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic disease
    • Cope A.P., Aderka D., Aderka D.et al. Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic disease. Arthritis Rheum. 35:1992;1160-1169.
    • (1992) Arthritis Rheum. , vol.35 , pp. 1160-1169
    • Cope, A.P.1    Aderka, D.2    Aderka, D.3
  • 13
    • 0027201923 scopus 로고
    • Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor-α and interleukin-6 levels in rheumatoid arthritis
    • Barrera P., Boerbooms A.M., Janssen E.M.et al. Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor-α and interleukin-6 levels in rheumatoid arthritis. Arthritis Rheum. 36:1993;1070-1079.
    • (1993) Arthritis Rheum. , vol.36 , pp. 1070-1079
    • Barrera, P.1    Boerbooms, A.M.2    Janssen, E.M.3
  • 14
    • 0028908490 scopus 로고
    • Soluble receptors for tumor necrosis factor and interleukin-2 in serum and synovial fluid of patients with rheumatoid arthritis, reactive arthritis and osteoarthritis
    • Steiner G., Studnicka-Benke A., Witzmann G., Hofler E., Smolen J. Soluble receptors for tumor necrosis factor and interleukin-2 in serum and synovial fluid of patients with rheumatoid arthritis, reactive arthritis and osteoarthritis. J. Rheumatol. 22:1995;406-412.
    • (1995) J. Rheumatol. , vol.22 , pp. 406-412
    • Steiner, G.1    Studnicka-Benke, A.2    Witzmann, G.3    Hofler, E.4    Smolen, J.5
  • 15
    • 0000032082 scopus 로고
    • Elevated soluble IL-2 receptor levels in the sera and synovial fluids of patients with rheumatoid arthritis
    • Keystone E.C., Snow K.M., Bombardier C., Chang C.H., Nelson D.L., Rubin L.A. Elevated soluble IL-2 receptor levels in the sera and synovial fluids of patients with rheumatoid arthritis. Arthritis Rheum. 31:1988;1358-1364.
    • (1988) Arthritis Rheum. , vol.31 , pp. 1358-1364
    • Keystone, E.C.1    Snow, K.M.2    Bombardier, C.3    Chang, C.H.4    Nelson, D.L.5    Rubin, L.A.6
  • 16
    • 0023685344 scopus 로고
    • Soluble IL-2 receptor in rheumatoid arthritis: Correlation with disease activity, IL-1 and IL-2 inhibition
    • Symons J.A., Wood N.C., Di Giovine F.S., Duff G.W. Soluble IL-2 receptor in rheumatoid arthritis: correlation with disease activity, IL-1 and IL-2 inhibition. J. Immunol. 141:1988;2612-2618.
    • (1988) J. Immunol. , vol.141 , pp. 2612-2618
    • Symons, J.A.1    Wood, N.C.2    Di Giovine, F.S.3    Duff, G.W.4
  • 17
    • 0025301038 scopus 로고
    • Serial levels of soluble interleukin 2 receptor in the peripheral blood of patients with rheumatoid arthritis: Correlations with disease activity
    • Rubin L.A., Snow K.M., Kurman C.C., Nelson D.L., Keystone E.C. Serial levels of soluble interleukin 2 receptor in the peripheral blood of patients with rheumatoid arthritis: correlations with disease activity. J. Rheumatol. 17:1990;597-602.
    • (1990) J. Rheumatol. , vol.17 , pp. 597-602
    • Rubin, L.A.1    Snow, K.M.2    Kurman, C.C.3    Nelson, D.L.4    Keystone, E.C.5
  • 18
    • 0029591977 scopus 로고
    • SIL-2R levels in rheumatoid arthritis: Poor correlation with clinical activity is due to part to disease duration
    • Tebib J.G., Letroublon M.C., Bienvenu J., Bouvier M. sIL-2R levels in rheumatoid arthritis: poor correlation with clinical activity is due to part to disease duration. Br. J. Rheumatol. 34:1995;1037-1040.
    • (1995) Br. J. Rheumatol. , vol.34 , pp. 1037-1040
    • Tebib, J.G.1    Letroublon, M.C.2    Bienvenu, J.3    Bouvier, M.4
  • 19
    • 0022546266 scopus 로고
    • Urinary neopterin reflects clinical activity in patients with rheumatoid arthritis
    • Reibnegger G., Egg D., Fuchs D.et al. Urinary neopterin reflects clinical activity in patients with rheumatoid arthritis. Arthritis Rheum. 29:1986;1063-1070.
    • (1986) Arthritis Rheum. , vol.29 , pp. 1063-1070
    • Reibnegger, G.1    Egg, D.2    Fuchs, D.3
  • 20
    • 0022501637 scopus 로고
    • Neopterin production in inflamed knee joints: High levels in synovial fluids
    • Maerker-Alzer G., Diemer O., Strumper R., Rohe M. Neopterin production in inflamed knee joints: high levels in synovial fluids. Rheumatol. Int. 6:1986;151-154.
    • (1986) Rheumatol. Int. , vol.6 , pp. 151-154
    • Maerker-Alzer, G.1    Diemer, O.2    Strumper, R.3    Rohe, M.4
  • 21
    • 0141427874 scopus 로고    scopus 로고
    • Homocysteine accumulates in supernatants of stimulated human peripheral blood mononuclear cells
    • Schroecksnadel K., Frick B., Wirleitner B., Schennach H., Fuchs D. Homocysteine accumulates in supernatants of stimulated human peripheral blood mononuclear cells. Clin. Exp. Immunol. 134:2003;53-56.
    • (2003) Clin. Exp. Immunol. , vol.134 , pp. 53-56
    • Schroecksnadel, K.1    Frick, B.2    Wirleitner, B.3    Schennach, H.4    Fuchs, D.5
  • 23
    • 0033533505 scopus 로고    scopus 로고
    • Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): Population reference ranges and contribution of vitamin status to high serum concentrations
    • Selhub J., Jacques P.F., Rosenberg I.H.et al. Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): population reference ranges and contribution of vitamin status to high serum concentrations. Ann. Intern. Med. 131:1999;331-339.
    • (1999) Ann. Intern. Med. , vol.131 , pp. 331-339
    • Selhub, J.1    Jacques, P.F.2    Rosenberg, I.H.3
  • 24
    • 0034900823 scopus 로고    scopus 로고
    • The relation between plasma cysteine, plasma homocysteine and coronary atherosclerosis
    • van den Brandhof W.E., Haks K., Schouten E.G., Verhoef P. The relation between plasma cysteine, plasma homocysteine and coronary atherosclerosis. Atherosclerosis. 157:2001;403-409.
    • (2001) Atherosclerosis. , vol.157 , pp. 403-409
    • Van Den Brandhof, W.E.1    Haks, K.2    Schouten, E.G.3    Verhoef, P.4
  • 26
    • 0028181516 scopus 로고
    • Increased serum concentrations of soluble tumor necrosis factor receptors in HIV-infected individuals are associated with immune activation
    • Zangerle R., Gallati H., Sarcletti M.et al. Increased serum concentrations of soluble tumor necrosis factor receptors in HIV-infected individuals are associated with immune activation. J. Acquir. Immune Defic. Syndr. 7:1994;79-85.
    • (1994) J. Acquir. Immune Defic. Syndr. , vol.7 , pp. 79-85
    • Zangerle, R.1    Gallati, H.2    Sarcletti, M.3
  • 27
    • 0027066967 scopus 로고
    • The role of neopterin as a monitor of cellular immune activation in transplantation, inflammatory, infectious and malignant diseases
    • Fuchs D., Weiss G., Reibnegger G., Wachter H. The role of neopterin as a monitor of cellular immune activation in transplantation, inflammatory, infectious and malignant diseases. Crit. Rev. Clin. Lab. Sci. 29:1992;307-341.
    • (1992) Crit. Rev. Clin. Lab. Sci. , vol.29 , pp. 307-341
    • Fuchs, D.1    Weiss, G.2    Reibnegger, G.3    Wachter, H.4
  • 29
    • 0028901371 scopus 로고
    • Redox status and protein binding of plasma homocysteine and other aminothiols in patients with early-onset peripheral vascular disease
    • Mansoor M.A., Bergmark C., Svardal A.M., Lonning P.E., Ueland P.M. Redox status and protein binding of plasma homocysteine and other aminothiols in patients with early-onset peripheral vascular disease. Arterioscler. Thromb. Vasc. Biol. 15:1995;232-240.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 232-240
    • Mansoor, M.A.1    Bergmark, C.2    Svardal, A.M.3    Lonning, P.E.4    Ueland, P.M.5
  • 30
    • 0036620060 scopus 로고    scopus 로고
    • Decreasing plasma endothelin-1 and unchanged plasma neopterin during folate supplementation in hyperhomocysteinemia
    • Gottsater A., Forsblad J., Mattiasson I., Lindgarde F. Decreasing plasma endothelin-1 and unchanged plasma neopterin during folate supplementation in hyperhomocysteinemia. Int. Angiol. 21:2002;158-164.
    • (2002) Int. Angiol. , vol.21 , pp. 158-164
    • Gottsater, A.1    Forsblad, J.2    Mattiasson, I.3    Lindgarde, F.4
  • 31
    • 0032849727 scopus 로고    scopus 로고
    • Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries
    • Erren M., Reinecke H., Junker R.et al. Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries. Arterioscler. Thromb. Vasc. Biol. 19:1999;2355-2363.
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 2355-2363
    • Erren, M.1    Reinecke, H.2    Junker, R.3
  • 35
    • 0034819473 scopus 로고    scopus 로고
    • Is hyperhomocysteinemia due to the oxidative depletion of folate rather than to insufficient dietary intake?
    • Fuchs D., Jaeger M., Widner B., Wirleitner B., Artner-Dworzak E., Leblhuber F. Is hyperhomocysteinemia due to the oxidative depletion of folate rather than to insufficient dietary intake? Clin. Chem. Lab. Med. 39:2001;691-694.
    • (2001) Clin. Chem. Lab. Med. , vol.39 , pp. 691-694
    • Fuchs, D.1    Jaeger, M.2    Widner, B.3    Wirleitner, B.4    Artner-Dworzak, E.5    Leblhuber, F.6
  • 36
    • 0034783872 scopus 로고    scopus 로고
    • Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and endothelial dysfunction in uremia
    • Mezzano D., Pais E.O., Aranda E.et al. Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and endothelial dysfunction in uremia. Kidney Int. 60:2001;1844-1850.
    • (2001) Kidney Int. , vol.60 , pp. 1844-1850
    • Mezzano, D.1    Pais, E.O.2    Aranda, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.