Effect of Chagas' disease on nitric oxide-containing neurons in severely affected and unaffected intestine

Diseases of the Colon and Rectum

Volumn 41, Issue 11, 1998, Pages 1411-1417

  Ribeiro Jr , Ulysses ^b,c   Safatle Ribeiro, Adriana Vaz ^a,c   Habr Gama, Angelita ^c   Gama Rodrigues, Joaquim J ^c   Sohn, Jackie ^a   Reynolds, James C ^a,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Chagas' disease; Megacolon; Neuronal nicotinamide adenine dinucleotide phosphate diaphorase; Nitric oxide synthase neurons

Indexed keywords

DIHYDROLIPOAMIDE DEHYDROGENASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; NITRIC OXIDE;

ANUS SPHINCTER; ARTICLE; CHAGAS DISEASE; COLON CANCER; DISEASE SEVERITY; ENZYME ACTIVITY; HUMAN; MEGACOLON; NERVE FIBER TRANSPORT; NEUROTRANSMISSION; TRYPANOSOMA CRUZI;

EID: 0344110541     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02237058     Document Type: Article

References (30)

1. Okumura M, Corrêa-Neto A. Produção experimental de megas em animais inoculados com Trypanosoma cruzi. Rev Hosp Cl'n Fac Med São Paulo 1961;18:5.
2. Koberle F. Chagas' disease and Chagas' syndrome. The pathology of American trypanosomiasis. Adv Parasitol 1968;6:63-116.
3. Habr-Gama A, Raia A, Corrêa Neto A. Motility of the sigmoid colon and rectum: contribution to the physiopathology of megacolon in Chagas' disease. Dis Colon Rectum 1971;14:291-304.
4. Burleigh DE, D'Mello A, Parks AG. Responses of isolated human internal anal sphincter to drugs and electrical field stimulation. Gastroenterology 1979;77:484-90.
5. Burleigh DE. Non-adrenergic non-cholinergic inhibitory neurons in the human internal anal sphincter muscle. J Pharm Pharmacol 1983;35:258-60.
6. G-monomethyl L-arginine on the response of the rat anococcygeus muscle to NANC nerve stimulation. Br J Pharmacol 1989;98:1080-2.
7. Li CG, Rand MJ. Evidence for a role of nitric oxide in the neurotransmitter system mediating relaxation of the rat anococcygeus muscle. Clin Exp Pharmacol Physiol 1989;16:933-8.
8. Bull H, Boeckxstaens GE, Pelckmans PA, Jordaens FH, Van Maercke YM, Herman AG. Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter. Nature 1990;345:346-7.
9. Sanders KM, Ward SM. Nitric oxide as a mediator of nonadrenergic noncholinergic neurotransrnission. Am J Physiol 1992;262:G3:79-92.
10. Keef KD, Du C, Ward SM, McGregor B, Sanders KM. Enteric inhibitory neural regulation of human colonic muscle: the role of nitric oxide. Gastroenterology 1993;105:1009-16.
11. Stebbing JF, Brading AF, Mortensen NJ. Nitrergic innervation and relaxant response of rectal circular smooth muscle. Dis Colon Rectum 1996;39:294-9.
12. Bredt DS, Hwang PM, Snyder SH. Localization of nitric oxide synthase indicating a neural role for nitric oxide. Nature 1990;347:768-70.
13. Costa M, Furness JB, Pompolo S, et al. Projections and chemical coding of neurons with immunoreactivity for nitric oxide synthase in the guinea-pig small intestine. Neurosci Lett 1992;148:121-5.
14. Young HM, Furness JB, Shuttleworth CW, Bredt DS, Snyder SH. Co-localization of nitric oxide synthase immunoreactivity and NADPH diaphorase staining in neurons of the guinea pig intestine. Histochemistry 1992;97:375-8.
15. Ward S, Xue C, Shuttleworth CW, Bredt DS, Snyder SH, Sanders KM. NADPH diaphorase and nitric oxide synthase co-localization in enteric nerves of the canine proximal colon. Am J Physiol 1992;263:G2:77-84.
16. Dawson TM, Bredt DS, Fotuhi M, Hwang PM, Snyder SH. Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc Natl Acad Sci USA 1991;88:7797-801.
17. Hope BT, Michael GJ, Knigge KM, Vincent SR. Neuronal NADPH diaphorase is a nitric oxide synthase. Proc Natl Acad Sci USA 1991;88:2811-4.
18. O'Kelly T, Brading A, Mortensen N. Nerve mediated relaxation of the human internal sphincter: the role of nitric oxide. Gut 1993;34:689-93.
19. Bealer JF, Natuzzi ES, Buscher C, et al. Nitric oxide synthase is deficient in the aganglionic colon of patients with Hirschsprung's disease. Pediatrics 1994;93:647-51.
20. Moore BG, Singaram C, Eckhoff DE, Gaumnitz EA, Starling JR. Immunohistochemical evaluation of ultra-short-segment Hirschsprung's disease: report of three cases. Dis Colon Rectum 1996;39:817-22.
21. Cuffari C, Rubin SZ, Krantis A. Routine use of the nitric oxide stain in the differential diagnosis of Hirschsprung's disease. J Pediatr Surg 1993;28:1202-4.
22. Vanderwinden JM, De Laet MH, Schiffmann SN, et al. Nitric oxide synthase distribution in the enteric nervous system of Hirschsprung's disease. Gastroenterology 1993;105:969-73.
23. O'Kelly TJ, Brading AF, Mortensen NJ. Nerve mediated relaxation of the human internal anal sphincter: the role of nitric oxide. Gut 1993;34:689-93.
24. Gustafsson BI, Delbro DS. Tonic inhibition of small intestinal motility by nitric oxide. J Auton Nerv Syst 1993;44:179-87.
25. Middleton SJ, Cuthbert AW, Shorthouse M, Hunter JO. Nitric oxide affects mammalian distal colonic muscle by tonic neural inhibition. Br J Pharmacol 1993;108:974-9.
26. Rattan S, Sarkar A, Chadker S. Nitric oxide pathway in rectoanal inhibitory reflex of opossum internal anal sphincter. Gastroenterology 1992;103:43-50.
27. O'Kelly TJ, Davies JR, Brading AF, Mortensen NJ. Dis-tribution of nitric oxide synthase containing neurons in the rectal myenteric plexus and canal anal: morphologic evidence that nitric oxide mediates the rectoanal inhibitory reflex. Dis Colon Rectum 1994;37:350-7.
28. Loder PB, Kamm MA, Nicholls RJ, Phillips RK. Reversible chemical sphincterotomy by local application of glyceryl trinitrate. Br J Surg 1994;81:1386-9.
29. Lund JN, Sholefield JH, A randomised, prospective, double-bind, placebo-controlled trial of glyceryl trinitrate ointment in treatment of anal fissure. Lancet 1997;349:11-4.
30. Schouten WR, Briel JW, Boerma MO, Auwerda JJ, Wilms EB, Graatsma BH. Pathophysiological aspects and clinical outcome of intra-anal application of isosorbide dinitrate in patients with chronic anal fissure. Gut 1996;39:465-9.