Structure activity relationship of homochiral 7-substituted 1- Aminoindans as 5-HT(1A) receptor ligands

Archiv der Pharmazie

Volumn 331, Issue 2, 1998, Pages 59-71

  Landsiedel Maier, Dorothea ^a   Frahm, August Wilhelm ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

5 HT receptor subtypes; 5 HT(1A) receptor selectivity; 7 Substituted 1 aminoindans; Absolute configuration; Asymmetric synthesis; Binding studies; Functional test; HeLa cell culture; Structure activity relationship

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 7 BENZYLAMIDO 1 (1 PHENYLETHYLAMINO)INDAN; 7 METHOXY 1 (DI N PROPYLAMINO)INDAN HYDROGENEMBONATE; 7 PROPOXY 1 (DI N PROPYLAMINO)INDAN; CYCLIC AMP; FORSKOLIN; INDAN DERIVATIVE; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0344110347     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4184(199802)331:2<59::AID-ARDP59>3.3.CO;2-4     Document Type: Article

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