Carboxypeptidase G2 rescue in methotrexate intoxication;Sauvetage de l'intoxication au methotrexate par la carboxypeptidase-G2

Bulletin du Cancer

Volumn 85, Issue 12, 1998, Pages 1066-

  Grill, Jacques ^a   Amigo Ferreiro, Maria Elena ^a   Schoepfer, Caroline ^a   Bonnay, Marc ^a   Valteau Couanet, Dominique ^a   Hartmann, Olivier ^a   Vassal, Gilles ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE G2; CREATININE; FOLINIC ACID; GLUTAMIC ACID; METHOTREXATE; THYMIDINE;

DRUG TOXICITY; HUMAN; INTRATHECAL DRUG ADMINISTRATION; KIDNEY FAILURE; LETTER; MORBIDITY; OSTEOSARCOMA;

ADOLESCENT; ANTIMETABOLITES, ANTINEOPLASTIC; BONE NEOPLASMS; GAMMA-GLUTAMYL HYDROLASE; HUMANS; MALE; METHOTREXATE; OSTEOSARCOMA; POISONING;

EID: 0344097397     PISSN: 00074551     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Letter

References (3)

1. 1. Widemann BC, Balis FM, Murphy RF, Sorensen JM, Montello MJ, O'Brien M, et al. Carboxypeptidase-G2, thymidine and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction. J Clin Oncol 1997 ; 15 : 2125-34.
2. 2. Bleyer WA. Methotrexate : clinical pharmacology, current status and therapeutic guidelines. Cancer Treat Rev 1977 ; 4 : 87-101.
3. 3. O'Marcaigh AS, Johnson CM, Smithson WA, Patterson MC, Widemann BC, Adamson PC, et al. Successful treatment of intrathecal methotrexate overdose by using ventriculolumbar perfusion and intrathecal instillation of carboxypeptidase G2. Mayo Clin Proc 1996 ; 71 : 161-5.