Imatinib mesylate-induced molecular remission of Philadelphia chromosome-positive myelodysplastic syndrome [3]

Leukemia

Volumn 17, Issue 2, 2003, Pages 463-465

  Drummond, M W ^a   Lush, C J ^b   Vickers, M A ^c   Reid, F M ^a   Kaeda, J ^d   Holyoake, T L ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b RAIGMORE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

^d MRD Group   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BCR ABL PROTEIN; DAUNORUBICIN; IMATINIB;

AGED; ANEMIA; CANCER REGRESSION; CASE REPORT; CHROMOSOME ANALYSIS; CHROMOSOME TRANSLOCATION 22; CHROMOSOME TRANSLOCATION 9; CONTROLLED STUDY; CYTOGENETICS; ERYTHROCYTE TRANSFUSION; FEMALE; HUMAN; LETTER; MOLECULAR GENETICS; MYELODYSPLASTIC SYNDROME; NEUTROPENIA; PANCYTOPENIA; PHILADELPHIA 1 CHROMOSOME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL TIME; THROMBOCYTOPENIA;

EID: 0344089317     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402814     Document Type: Letter

References (8)

1. Jacobs RH, Cornbleet MA, Vardiman JW, Larson RA, Lebeau MM, Rowley JD. Prognostic implications of morphology and karyotype in primary myelodysplastic syndromes. Blood 1986; 76: 1765-1772.
2. Melo J. The diversity of Bcr-Abl fusion proteins and their relationship to leukaemia phenotype. Blood 1996; 88: 2375-2384.
3. Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM, Lydon NB, Kantarjian H, Capdeville R, Ohno-Jones S, Sawyers CL. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001; 344: 1031-1037.
4. Verhoef G, Meeus P, Stul M, Mecucci C, Cassiman J, Van Den Berghe H, Boogaerts M. Cytogenetic and molecular studies of the Philadelphia translocation in myelodysplastic syndromes. Cancer Genet Cytogenet 1992; 59: 161-166.
5. Jaffe ES, Harris NL, Stein H, Vardiman JW. WHO classification of tumours: pathology and genetics of tumours of haematopoietic and lymphoid tissues. In: Kleihues P, Sobin LH (eds). WHO Classification of Tumours, 1st edn. IARC Press: Lyon, 2001, pp 63-73.
6. Germing U, Gattermann N, Strupp C, Aivado M, Aul C. Validation of the WHO proposals for a new classification of primary myelodysplastic syndromes: a retrospective analysis of 1600 patients. Leukemia Res 2000; 24: 983-992.
7. Cross NCP, Feng L, Chase A, Bungey J, Hughes TP, Goldman JM. Competitive polymerase chain reaction to estimate the number of BCR-ABL transcripts in chronic myeloid leukemia patients after bone marrow transplantation. Blood 1993; 82: 1929-1936.
8. Vickers MA, McLeod E, Spector TD, Wilson IJ. Assessment of mechanism of acquired skewed X inactivation by analysis of twins. Blood 2001; 97: 1274-1281.