Benzodiazepine-induced amnesia in rats: Reinstatement of conditioned performanced by noxious stimulation on test

Behavioral Neuroscience

Volumn 112, Issue 1, 1998, Pages 183-192

  Harris, Justin A ^a   Westbrook, R Frederick ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE DERIVATIVE; FORMALDEHYDE; MIDAZOLAM;

AMNESIA; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDITIONING; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; FEAR; MALE; NOCICEPTIVE STIMULATION; NONHUMAN; RAT; TASK PERFORMANCE;

AMYGDALA; ANIMALS; ANTI-ANXIETY AGENTS; ASSOCIATION LEARNING; BRAIN MAPPING; CONDITIONING, CLASSICAL; ELECTROSHOCK; FEAR; MALE; MENTAL RECALL; MIDAZOLAM; MOTOR ACTIVITY; PAIN THRESHOLD; RATS; RATS, WISTAR; RETENTION (PSYCHOLOGY);

EID: 0344074027     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.112.1.183     Document Type: Article

References (39)

1. Abbott, F. V., Franklin, K. B. J., & Westbrook, R. F. (1995). The formalin test: Scoring properties of the first and second phases of the pain response in rats. Pain, 60, 91-102.
2. Blanchard, D. C., & Blanchard, R. J. (1972). Innate and conditioned reactions to threat in rats with amygdaloid lesions. Journal of Comparative Physiology and Psychology, 81, 281-290.
3. Brandon, S. E., Bombace, J. C., Falls, W. A., & Wagner, A. R. (1991). Modulation of unconditioned defensive reflexes by a putative emotional Pavlovian conditioned stimulus. Journal of Experimental Psychology: Animal Behavior Processes, 17, 312-322.
4. Brown, J. S., Kalish, H., & Farber, I. E. (1951). Conditioned fear as revealed by magnitude of startle response to an auditory stimulus. Journal of Experimental Psychology, 41, 317-328.
5. Cole, B. J., & Hillmann, M. (1994). Effects of benzodiazepine receptor ligands on the performance of an operant delayed matching to position task in rats: Opposite effects of FG 7142 and lorazepam. Psychopharmacology, 115, 350-357.
6. Davis, M. (1986). Pharmacological and anatomical analysis of fear conditioning using the potentiated startle paradigm. Behavioral Neuroscience, 100, 808-818.
7. Davis, M. (1992). The role of the amygdala in conditioned fear. In J. P. Aggleton (Ed.), The amygdala: Neurobiological aspects of emotion, memory and mental dysfunction (pp. 255-305). New York: Wiley-Liss.
8. Dickinson-Anson, H., & McGaugh, J. L. (1993). Midazolam administered into the amygdala impairs retention of an inhibitory avoidance task. Behavioral and Neural Biology, 60, 84-87.
9. Dickinson-Anson, H., Mesches, M. H., Coleman, K., & McGaugh, J. L. (1993). Bicuculline administered into the amygdala blocks benzodiazepine-induced amnesia. Behavioral and Neural Biology, 60, 1-4.
10. Fanselow, M. S. (1980). Conditional and unconditional components of post-shock freezing. Pavlovian Journal of Biological Sciences, 15, 177-182.
11. Fanselow, M. S. (1986). Associative vs. topographical accounts of the immediate shock freezing deficit in rats: Implications for the response selection rules governing species specific defensive reactions. Learning and Motivation, 17, 16-39.
12. Fanselow, M. S. (1990). Factors governing one-trial contextual conditioning. Animal Learning and Behavior, 18, 264-270.
13. Fanselow, M. S., & Helmstetter, F. J. (1988). Conditional analgesia, defensive freezing, and benzodiazepines. Behavioral Neuroscience, 102, 233-243.
14. Flaherty, C. F. (1990). Effects of anxiolytics and antidepressants on extinction and negative contrast. Pharmacology and Therapeutics, 46, 309-320.
15. Gray, J. A. (1977). Drug effects on fear and frustration: Possible limbic site of action of minor tranquilizers. In L. L. Iversen, S. D. Iversen, & S. H. Snyder (Eds.), Handbook of psychopharmacology: Drugs, neurotransmitters, and behavior (Vol. 8. pp. 433-529). New York: Plenum Press.
16. Gray, J. A. (1982). The neuropsychology of anxiety: An inquiry into the junctions of the septo-hippocampal system. Oxford, England: Oxford University Press.
17. Harris, J. A., McGregor, I. S., & Westbrook, R. F. (1993). Low and high doses of midazolam differentially affect hypoalgesia in rats conditioned to a heat stressor. Psychopharmacology, 111, 62-68.
18. Harris, J. A., & Westbrook, R. F. (1994). Effects of midazolam and naloxone in rats tested for sensitivity/reactivity to formalin pain in a familiar, novel or aversively conditioned environment. Psychopharmacology, 115, 65-72.
19. Harris, J. A., & Westbrook, R. F. (1995). Effects of benzodiazepine micro-injection into the amygdala or periaqueductal gray upon the expression of conditioned fear and hypoalgesia in rats. Behavioral Neuroscience, 109, 295-304.
20. Harris, J. A., & Westbrook, R. F. (1996). Midazolam impairs the acquisition of conditioned analgesia if rats are tested with an acute but not a chronic noxious stimulus. Brain Research Bulletin, 39, 227-233.
21. Haefely, W. E. (1990). The GABAA-benzodiazepine receptor: Biology and pharmacology. In G. D. Burrows, M. Roth, & R. Noyes, Jr. (Eds.), Handbook of anxiety: The neurobiology of anxiety (vol. 3, pp. 165-188). New York: Elsevier.
22. Hays, W. L. (1972). Statistics for the social sciences. New York: Holt, Rinehart & Winston.
23. Kiernan, M. J., & Westbrook, R. F. (1993). Effects of exposure to a to-be-shocked environment upon the rat's freezing response: Evidence for facilitation, latent inhibition and perceptual learning. Quarterly Journal of Experimental Psychology, 46B, 271-288.
24. Konorski, J. (1967). Integrative activity of the brain. Chicago: University of Chicago Press.
25. LeDoux, J. E. (1992). Brain mechanisms of emotion and emotional learning. Current Opinion in Neurobiology, 2, 191-197.
26. LeDoux, J. E. (1995). In search of an emotional system in the brain: Leaping from fear to emotion and consciousness. In M. S. Gazzaniga (Ed.), The cognitive neurosciences (pp. 1049-1061). Cambridge, MA: MIT Press.
27. Maren, S., & Fanselow, M. S. (1996). The amygdala and fear conditioning: Has the nut been cracked? Neuron, 16, 237-240.
28. Paxinos, G., & Watson, C. (1986). The rat brain in stereotaxic coordinates (2nd ed.). San Diego, CA: Academic Press.
29. Rodger, R. S. (1967). Type II errors and their decision basis. British Journal of Mathematical and Statistical Psychology, 20B, 187-204.
30. Rothschild, A. J. (1992). Disinhibition, amnestic reactions, and other adverse reactions secondary to triazolam: A review of the literature. Journal of Clinical Psychiatry, 53(Suppl.), 69-79.
31. Rudy, J. W., & Morledge, P. (1994). The ontogeny of contextual fear conditioning: Implications for consolidation, infantile amnesia, and hippocampal system function. Behavioral Neuroscience, 108, 227-234.
32. Stackman, R. W., & Walsh, T. J. (1992). Chlordiazepoxide-induced working memory impairments: Site specificity and reversal by flumazenil (RO15-1788). Behavioral and Neural Biology, 57, 233-243.
33. Thiébot, M.-H. (1985). Some evidence for amnesic-like effects of benzodiazepines in animals. Neuroscience & Biobeharioral Reviews, 9, 95-100.
34. Tohyama, K., Nabeshimu, T. Ichihara, K., & Kameyama, T. (1991). Involvement of GABAergic systems in benzodiazepine-induced impairment of passive avoidance learning in mice. Psychopharmacology, 105, 22-26.
35. Tomaz, C., Dickinson-Anson, H., & McGaugh, J. L. (1991). Amygdala lesions block the amnestic effects of diazepam. Brain Research, 568, 85-91.
36. Tomaz, C., Dickinson-Anson, H., & McGaugh, J. L. (1992). Basolateral amygdala lesions block diazepam-induced anterograde amnesia in an inhibitory avoidance task. Proceedings of the National Academy of Sciences USA, 89, 3615-3619.
37. Venault, P., Chapouthier, G., de Carvalho, L. P., Simiand, J., Morre, M., Dodd, R. H., & Rossier, J. (1986). Benzodiazepine impairs and beta-carboline enhances performance in learning and memory tasks. Nature, 321, 864-866.
38. Wagner, A. R., & Brandon, S. E. (1989). Evolution of a structured connectionist model of Pavlovian conditioning (ÆSOP). In S. B. Klein & R. R. Mowrer (Eds.), Contemporary learning theories (pp. 149-189). Hillsdale, NJ: Erlbaum.
39. Westbrook, R. F., Greeley, J. D., Nabke, C. P., & Swinbourne, A. L. (1991). Aversive conditioning in the rat: Effects of a benzodiazepine and of an opioid agonist and antagonist on conditioned hypoalgesia and fear. Journal of Experimental Psychology: Animal Behavior Processes, 17, 219-230.