Modeling and Control of a Microthermal Cycler for DNA Polymerase Chain Reaction

Industrial and Engineering Chemistry Research

Volumn 42, Issue 24, 2003, Pages 6104-6111

  Sung, Su Whan ^a   Park, Sunwon ^b   Yoon, Dae Sung ^c   Lee, Youngsun ^c   Lim, Geunbae ^c  

^a LG Chemical Ltd   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^c Samsung Advanced Institute of Technology (SAIT)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER SOFTWARE; CONTROL SYSTEMS; DNA; MICROSENSORS;

MICROTHERMAL CYCLERS; POLYMERASE CHAIN REACTION;

BIOREACTORS;

DNA POLYMERASE; PLATINUM;

DNA;

AUTOMATION; COMPUTER PROGRAM; CONFERENCE PAPER; DEVICE; DYNAMICS; MICROTHERMAL CYCLER; NONLINEAR SYSTEM; PERFORMANCE; POLYMERASE CHAIN REACTION; PREDICTION; SENSOR;

EID: 0344063369     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie030031d     Document Type: Conference Paper

References (9)

1. Belgrader, P.; Young, S.; Yuan, B.; Primeau, M.; Christel, L. A.; Pourahmadi, F.; Northrup, M. A. A Battery-Powered Notebook Thermal Cycler for Rapid Multiplex Real-Time PCR Analysis. Anal. Chem. 2001, 73, 286.
2. Northrup, M. A.; Benett, B.; Hadley, D.; Landre, P.; Lehew, S.; Richards, J.; Stratton, P. A Miniature Analytical Instrument for Nucleic Acids Based on Micromachined Silicon Reaction Chambers. Anal. Chem. 1998, 70, 918.
3. Lao, A. I. Y.; Lee, T. M. H.; Hsing, I.; Ip, N. Y. Precise Temperature Control of Microfluidic Chamber for Gas and Liquid Phase Reactions, Sens. Actuators 2000, 84, 11.
4. Seborg, D. E.; Edgar, T. F.; Mellichamp, D. A. Process Dynamics and Control; John Wiley & Sons: New York, 1989
5. Sung, S. W.; Lee, I. Limitations and Countermeasures of PID Controllers. Ind. Eng. Chem. Res. 1996, 35, 2596.
6. Haber, R.; Unbehauen, H. Structure Identification of Non-linear Dynamic Systems-A Survey on Input/Output Approches. Automatica 1990, 26, 651.
7. Sung, S. W.; Lee, I. Prediction Error Method for Continuous-Time Processes with Time Delay. Ind. Eng. Chem. Res. 2001, 40, 5743.
8. Sung, S. W.; Lee, T.; Park, S. Optimal PID Controller Tuning Method for Single-Input-Single-Output (SISO) Processes. AIChE J. 2002, 48, 1358.
9. Morari, M.; Zafiriou, E. Robust Process Control; Prentice-Hall: Englewood Cliffs, NJ, 1989.