5-hydroxytryptamine is a mediator of 4-aminopyridine induced contractions in porcine and human isolated coronary arteries

Acta Biologica Szegediensis

Volumn 44, Issue 1-4, 2000, Pages 39-44

  Kun, Attila ^a   Pataricza, János ^a   Krassói, Irén ^b   Opincariu, Miklós ^a   Szécsi, János ^a   Papp, Julius Gy ^b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

4 aminopyridine; Human coronary artery; Porcine coronary artery; Voltage dependent potassium channel

Indexed keywords

EID: 0344060989     PISSN: 03246523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Adams DJ (1994) Ionic channels in vascular endothelial cells. Trends Cardiovasc Med 4:18-26.
2. Bryan LJ, O'Donnell SR, Williams AM (1989) Dissipation mechanisms for 5-hydroxytryptamine in the coronary circulation of the isolated perfused heart of the rat. Br J Pharm 97:329-338.
3. Cohen RA (1985) Platelet-induced neurogenic coronary contractions due to accumulation of the false neurotransmitter, 5-Hydroxytryptamine. J Clin Invest 75(1):286-292.
4. Cushing DJ, Cohen ML (1992) Comparison of the serotonin receptors that mediate smooth muscle contarction in canine and porcine coronary artery. J Pharm Exp Ther 261:856-862.
5. Fryer MW, Glover WE (1997) Effects of 4-methyl-2-aminopyridine on [3H]-noradrenaline overflow and contractility of isolated rabbit arteries. Gen Pharm 29(4):657-63.
6. Gollasch M, Ried C, Bychkov R, Luft FC, Haller H (1996) K+ currents in human coronary artery vascular smooth muscle cells. Circ Res 78(4):676-88.
7. Grissmer S (1997) Potassium channels still hot. Trends Pharm Sci 18:347-350.
8. + currents from rabbit isolated aortic smooth muscle cells. Br J Pharm 116:3139-3148.
9. Hara Y, Kitamura K, Kuriyama H (1980) Actions of 4-aminopyridine on vascular smooth muscle tissues of the guinea-pig. Br J Pharm 68:99-106.
10. Horst MA, Robinson CP (1985) Action of agonists and antagonists on adrenergic receptors in isolated porcine coronary arteries. Can J Physiol Pharm 63(7):867-871.
11. 2+ sensitivity and presynaptic control. Br J Pharm 102:764-768.
12. Iost N, Virág L, Opincariu M, Szécsi J, Varró A, Papp JGy (1998) Delayed rectifier potassium current in undiseased human ventricular myocytes. Cardiovasc Res 40:508-515.
13. Ishikawa T, Eckman DM, Keef KD (1997) Characterisation of delayed rectifier K+ currents in rabbit coronary artery cells near resting membrane potential. Can J Physiol Pharm 75(9):1116-22.
14. Knot HJ, Nelson MT (1995) Regulation of membrane potential and diameter by voltage-dependent K+ channels in rabbit myogenic cerebral arteries. Am J Physiol 269:H348-H355.
15. +-channel blockers on transmitter release in bullfrog sympathetic ganglia. J Pharm Exp Ther 235:241-247.
16. Nelson MT, Quayle JM (1995) Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol 268 (Cell Physiol 37):C799-C822.
17. O'Rourke ST (1996) Effects of potassium channel blockers on resting tone in isolated coronary arteries. J Cardiovasc Pharm 27:636-642.
18. + channels in canine pulmonary artrey. Novel mechanism for hypoxia-induced membrane depolarisation. Circ Res 77:131-139.
19. Quillen J, Sellke F, Banitt P, Harrison D (1992) The effect of norepinephrine on the coronary microcirculation. J Vasc Res 29(1):2-7.
20. Saito A, Lee J-F (1987) Serotonin as an alternative transmitter in sympathetic nerves of large cerebral arteries of the rabbit. Circ Res 60:220-228.
21. Szabó Cs, Hardebo JE, Owman C (1991) An amplifying effect of exogenous and neurally stored 5-hydroxytryptamine on the neurogenic contraction in rat tail artery. Br J Pharm 102:401-407.
22. Takeda K, Schini V, Stoeckel H, (1987) Voltage-activated potassium, but not calcium currents in cultured bovine aortic endothelial cells. Pflügers Arch 410:385-393.
23. Uchida Y, Nakamura F, Tomaru T, Sumino S, Kato A, Sugimoto T (1986) Phasic contractions of canine and human coronary arteries induced by potassium channel blockers. Jpn Heart J 27(5):727-740.
24. Varró A, Papp JGy (1995) Classification of positive inotropic actions based on electrophysiologic characteristics: where should calcium sensitizers be placed? J Cardiovasc Pharm 26(Suppl.1):S32-S44.