Contractile responses to various stimuli in isolated resistance vessels from simultaneously hypertensive and streptozotocin-diabetic rats

Journal of Cardiovascular Pharmacology

Volumn 27, Issue 1, 1996, Pages 167-175

  Kam, Kwee Lan ^a   Hendriks, Maarten G C ^a   Pijl, Aarnout J ^a   Van Marie, Jan ^a   Van Veen, Henk A ^a   Pfaffendorf, Martin ^a   Van Zwieten, Pieter A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

1 Adrenoceptors; Hypertension; Morphology; Small arteries; Streptozotocin; Vasoconstriction

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; METHOXAMINE; NORADRENALIN; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; HEMODYNAMIC MONITORING; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RESISTANCE BLOOD VESSEL;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CALCIUM CHLORIDE; DIABETES MELLITUS, EXPERIMENTAL; HYPERTENSION; MALE; MESENTERIC ARTERIES; METHOXAMINE; MUSCLE CONTRACTION; NOREPINEPHRINE; POTASSIUM CHLORIDE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SEROTONIN; SEROTONIN AGONISTS; STREPTOZOCIN; VASCULAR RESISTANCE;

EID: 0344059719     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199601000-00026     Document Type: Article

References (38)

1. Christlieb AR, Diabetes and hypertensive vascular disease. Mechanisms and treatment. Am J Cardiol 1973;32:592-606.
2. Epstein M, Sowers JR. Diabetes mellitus and hypertension. Hypertension 1992;19:403-18.
3. Trost BN. Hypertension in the diabetic patient. Drugs 1989; 38:621-33.
4. Hsueh WA, Anderson PW. Hypertension, the endothelial cell, and the vascular complications of diabetes mellitus. Hypertension 1992;20:253-63.
5. The hypertension in diabetes study group. Hypertension in diabetes study (HDS): I. Prevalence of hypertension in newly presenting type 2 diabetic patients and the association with risk factors for cardiovascular and diabetic complications. J Hypenens 1993;11:309-17.
6. The hypertension in diabetes study group. Hypertension in diabetes study (HDS): II. Increased risk of cardiovascular complications in hypertensive type 2 diabetic patients. J Hypertens 1993;11:319-25.
7. Airaksinen KEJ, Salmela PI, Linnaluoto MK, Ikäheimo MJ, Ahola K, Ryhänen LJ. Diminished arterial elasticity in diabetes: association with fluorescent advanced glycosylation end products in collagen, Cardiovasc Res 1993;27:942-5.
8. Webb RC. Vascular changes in hypertension. In: Antonaccio M, ed. Cardiovascular pharmacology, 2nd ed. New York: Raven Press, 1984:215-55.
9. Mulvany MJ. Editorial review. The fourth Sir George Pickering memorial lecture. The structure of the resistance vasculature in essential hypertension. J Hypertens 1987;5:129-36.
10. Cooper ME, Allen TJ, O'Brien RC, et al. Effects of genetic hypertension on diabetic nephropathy in the rat-functional and structural characteristics. J Hypertens 1988;6:1009-16.
11. Mulvany MJ. Changes to the vascular system resulting from hypertension and their effects on response to therapy. Drug 1990;39(suppl 1):9-20.
12. Folkow B. "Structural factor" in primary and second hypertension. Hypertension 1990;16:89-101.
13. Heagerty AM, Aalkjaer C, Bund SJ, Korsgaard N, Mulvany MJ. Small artery structure in hypertension. Dual processes of remodeling and growth. Hypertension 1993;21:391-7.
14. Aalkjaer C, Mulvany MJ. Morphological and mechanical properties of small mesenteric arteries and veins in spontaneously hypertensive rats. Acta Physiol Scand 1979;107: 309-12.
15. Tomlinson KC, Gardiner SM, Hebden RA, Bennett T. Functional consequences of streptozotocin-induced diabetes mellitus, with particular reference to the cardiovascular system. Pharmacol Rev 1992;44:103-50.
16. Owen MP, Carrier GO. Calcium dependence of norepinephrine-induced vascular contraction in experimental diabetes. J Pharmacol Exp Ther 1980;212:253-8.
17. MacLeod KM, McNeill JH. The influence of chronic experimental diabetes on contractile responses of rat isolated blood vessels. Can J Physiol Pharmacol 1985;63:52-7.
18. Agrawal DK, Bhimji S, McNeill JH. Effect of chronic experimental diabetes on vascular smooth muscle function in rabbit carotid artery. J Cardiovasc Pharmacol 1987;9:584-7.
19. Fiol de Cuneo M, Ruiz RD, Lacuara JL, Santillan de Torres R. Contractility and pharmacological reactivity of isolated vascular smooth muscle from diabetic rats. Pharmacology 1988;36:228-37.
20. Hebden RA, Doroudian A, Mcneill JH. Evidence for regionally selective changes in response to potassium chloride but not vasopressin or methoxamine in vasculature from diabetic rats. Can J Physiol Pharmacol 1988;666:1464-7.
21. Mulhern M, Docherty JR. Effects of experimental diabetes on the responsiveness of rat aorta. Br J Pharmacol 1989;97: 1007-12.
22. 1,-adrenoceptor stimulation in the absence and presence of extracellular calcium. J Cardiovasc Pharmacol 1990;16:239-48.
23. 2, but not noradrenaline, of aortae from rats with streptozotocininduced diabetes mellitus. Br J Pharmacol 1991;104:928-32.
24. Rinaldi GJ, Cingolani HE. Effect of diabetes on fast response to norepinephrine in rat aorta. Diabetes 1992;41: 30-4.
25. +-induced contraction in isolated aorta from diabetic and age-matched control rats. Pharmacology 1993;46:193-7.
26. Factor SM, Minase T, Cho S, Fein F, Capasso JM, Sonnenblick EH. Coronary microvascular abnormalities in the hypertensive-diabetic rat. Am J Pathol 1984;116:9-20.
27. Agrawal DK, McNeill JH. Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery. Can J Physiol Pharmacol 1986;65:2274-80.
28. Hendriks MGC, Kam KL, Pijl AJ, Pfaffendorf M, van Zwi-eten PA. The effects of hypertension and diabetes mellitus on the vascular reactivity of resistance arteries. Blood Pressure 1993;2:69-76.
29. Davis MJ, Ferrer PN, Gore RW. Vascular anatomy and hydrostatic pressure profile in the hamster cheek pouch. Am J Physiol 1986;250:H291-303.
30. Mulvany MJ. Structure and function of small arteries in hypertension. J Hypertens 1990;8(suppl 7):S225-32.
31. Mulvany MJ, Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ Res 1977;41:19-26.
32. De Mey JG, Defreyn G, Lenaers A, Calderon P, Roba J. Arterial reactivity, blood pressure, and plasma levels of atrial natriuretic peptides in normotensive and hypertensive rats: effects of acute and chronic administration of atriopeptin III. J Cardiovasc Pharmacol 1987;9:525-35.
33. x values in the analysis of pharmacodynamics. Arch Int Pharmacodyn 1957;110:275-99.
34. Mulvany MJ, Hansen PK, Aalkjaer C. Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers. Circ Res 1978;43:854-64.
35. Warshaw DM, Mulvany MJ, Halpern W. Mechanical and morphological properties of arterial resistance vessels in young and old spontaneously hypertensive rats. Circ Res 1979;45:250-9.
36. Mulvany MJ, Aalkjaer C, Christensen J. Changes in noradrenaline sensitivity and morphology of arterial resistance vessels during development of high blood pressure in spontaneously hypertensive rats. Hypertension 1980;2:664-71.
37. Aalkjaer C, Heagerty AM, Petersen KK, Smales JD, Mulvany MJ. Evidence for increased media thickness, increased neuronal amine uptake, and depressed excitationcontraction coupling in isolated resistance vessels from essential hypertensives. Circ Res 1987;61:181-6.
38. Furman BL, Sneddon P. Endothelium-dependent vasodilator responses of the isolated mesenteric bed are preserved in long-term streptozotocin diabetic rats. Eur J Pharmacol 1993;232:29-34.