(CAG)nCAA and GGN repeats in the human androgen receptor gene are not associated with prostate cancer in a French-German population

European Journal of Human Genetics

Volumn 7, Issue 3, 1999, Pages 357-362

  Correa Cerro, Lina ^d   Wöhr, Gudrun ^d   Haüssler, Jürgen ^d   Berthon, Philippe ^a   Drelon, Eric ^a   Mangin, Philippe ^a   Fournier, Georges ^b   Cussenot, Oliver ^a   Kraus, Petra ^d   Just, Walter ^d   Paiss, Thomas ^d   Cantú, José María ^d   Vogel, Walther ^c  

^a SAINT LOUIS HOSPITAL   (France)

^b SERVICE DE RHUMATOLOGIE   (France)

^c UNIVERSITY OF ULM   (Germany)

^d NONE

Author keywords

CAG and GGC microsatellites; Human androgen receptor gene; Prostate cancer

Indexed keywords

ANDROGEN RECEPTOR;

ADULT; AGED; ALLELE; ARTICLE; CANCER RISK; CANCER STATISTICS; CONTROLLED STUDY; EXON; FRANCE; GENETIC POLYMORPHISM; GERMANY; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE REPEAT; POPULATION GENETICS; PRIORITY JOURNAL; PROSTATE CANCER; RECEPTOR GENE;

EID: 0344052663     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200298     Document Type: Article

References (20)

1. Wang C, Uchida T: Androgen receptor gene mutations in prostate cancer. Nippon Hinyokika Gakkai Zasshi 1997; 88: 550-556.
2. Ross RK, Henderson BE: Do diet and androgens alter prostate cancer risk via a common etiological pathway? J Natl Cancer Inst 1994; 86: 252-254.
3. Online Mendelian Inheritance in Man, OMIM (TM): John Hopkins University, Baltimore, MD. MIM Number: 313700: 1/27/1998: World Wide Web URL: http:/ /www.ncbi.nlm.nih.gov/omim/
4. Irvine RA, Yu MC, Ross RK, Coetzee GA: The CAG and GGC microsatellites of the androgen receptor gene are in linkage disequilibrium in men with prostate cancer. Cancer Res 1995; 55: 1937-1940.
5. Lumbroso Rose, Beitel LK, Vasiliou DM, Trifiro MA, Pinsky L: Codon-usage variants in the polymorphic (GGN)n trinucleotide repeat of the human androgen receptor gene. Hum Genet 1997; 101: 43-46.
6. Giovannucci E, Stampfer MJ, Krithivas K et al: The CAG repeat within the androgen receptor gene and its relationship to prostate cancer. Proc Natl Acad Sci USA 1997; 94: 3320-3323.
7. Edwards A, Hammond HA, Jun L, Caskey T, Chakraborty R: Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups Genomics 1992; 12: 241-253.
8. Kazemi-Esfarjani P, Trifiro MA, Pinsky L: Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: possible pathogenetic relevance for the (CAG)n-expanded neuropathies. Hum Mol Genet 1995; 4: 523-527.
9. Ingles SA, Ross RK, Yu MC et al: Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor. J Natl Cancer Inst 1997; 89: 166-170.
10. Hardy DO, Scher III, Bogenreider T et al: Androgen receptor CAG repeats lengths in prostate cancer: correlation with age of onset. J Clin Endocrinol Metab 1996; 81: 4400-4405.
11. Stanford JL, Just JJ, Gibbs M et al: Polymorphic repeats in the androgen receptor gene: molecular markers of prostate cancer risk. Cancer Res 1997; 57: 1194-1198.
12. Sun S, Narod SA, Aprikian A, Ghadirian P, Labrie F: Androgen receptor and familial prostate cancer. Nat Med 1995; 1: 848-849.
13. Carter BS, Beaty TH, Steinberg GD, Childs B, Walsh PC: Mendelian inheritance of familial prostate cancer. Proc Natl Acad Sci USA 1992; 89: 3367-3371.
14. Berthon P, Valeri A, Cohen-Akenine A et al: Predisposing gene for early-onset prostate cancer, localized on chromosome 1q42.2-43. Am J Hum Genet 1998; 62: 1416-1424.
15. Schaid D, McDonell SK, Blute ML, Thibodeau SN: Evidence for autosomal dominant inheritance of prostate cancer. Am J Hum Genet 1998; 62: 1425-1438.
16. Smith JR, Freije D, Carpten JD et al: Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genomewide search. Science 1996; 274: 1371-1374.
17. Taylor JA, Hirvonen A, Watson M, Pittman G, Mohler JL, Bell DA: Association of prostate cancer with vitamin D receptor gene polymorphism. Cancer Res 1996; 56: 4108-4110.
18. Ingles SA, Coetzee GA, Ross RK et al: Association of prostate cancer with vitamin D receptor haplotypes in Africans-Americans. Cancer Res 1998; 58: 1620-1623.
19. Reichardt JKV, Makridakis N, Henderson BE, Yu MC, Pike MC, Ross RK: Genetic variability of the human SRD5A2 gene: implications for prostate cancer risk. Cancer Res 1995; 55: 3973-3975.
20. Abbaszadegan MR, Brown KM, Voeller JH, Sciavolire P, Abate-Shen C, Gelmann EP: Polymorphic allele of NKX3.1 a prostate specific homeobox gene is a possible risk factor for prostate cancer. Proc Am Assoc Cancer Res 1998; 39: 365.