Toxic Interaction of Lathyrus sativus and Manganese in Guinea Pig Intestine

Toxicology Mechanisms and Methods

Volumn 13, Issue 4, 2003, Pages 295-300

  Kumar, Manoj ^a   Kannan, A ^a   Upreti, R K ^a   Mishra, Geeta ^a   Khanna, S K ^a   Das, Mukul ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Brush Border Markers; Lathyrus sativus; Xenobiotic Metabolizing Enzymes; Diaminopropionic Acid; N Oxalyl L

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM MAGNESIUM); ALKALINE PHOSPHATASE; CHOLESTEROL; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HEXOSE; INTESTINE ENZYME; LATHYRUS EXTRACT; MANGANESE; PHOSPHOLIPID; PLANT EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SUCRASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DEPLETION; ENZYME INHIBITION; FEEDING; GASTROINTESTINAL TOXICITY; GUINEA PIG; INTESTINE BRUSH BORDER; INTESTINE CELL; LATHYRUS; LATHYRUS SATIVUS; MALE; NONHUMAN; PRIORITY JOURNAL; TOXICITY TESTING;

ANIMALIA; CAVIA; CAVIA PORCELLUS; LATHYRUS; LATHYRUS SATIVUS; SUS SCROFA;

EID: 0344012208     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/713857193     Document Type: Article

References (45)

1. Chase, R. A., Pearson, S., Nunn, P. B., and Lantos, P. L. 1985. Comparative toxicities of α- and β: 3, N-oxalyl-L-α-β -diaminopropionic acid to rat spinal cord. Neurosci. Lett. 55:89-94.
2. Cheema, P. S., Malathi, K., Padmanaban, G., and Sarma, P. S. 1969. The neurotoxicity of β-N-oxalyl-L-α,β-diaminopropionic acid, the neurotoxin from the pulse Lathyrus sativus. Biochem. J. 112:29-33.
3. Dahlqvist, A. 1964. Method for assay of intestinal disaccharidases. Anal. Biochem. 7:18-25.
4. Dehnen, W., Tomingas, R., and Roos, J. 1973. A modified method for the assay of benzo(a)pyrene hydroxylase. Anal. Biochem. 53:373-383.
5. De Young, L. M., Richards, W. L., Bonzelet, W., Tsai, L. L., and Boutwell, R. K., 1978. The localisation and significance of gamma glutaqmyl transpeptidase in normal and neoplastic mouse skin. Cancer Res. 38:3697-3701.
6. Dubey, R. K., and Singh, J. 1988a. Localisation and characterisation of drug metabolising enzymes along the villus-crypt surface of the rat small intestine. I. Biochem. Pharmacol. 37:169-176.
7. Dubey, R. K., and Singh, J. 1988b. Localisation and chracterisation of drug metabolising enzymes along the villus-crypt surface of the rat small intestine II. Biochem. Pharmacol. 37:177-184.
8. Dwivedi, M. P., and Prasad, B. G. 1964. An epidemiological study of lathyrism in the district of Rewa, Madhya Pradesh. Indian J. Med. Res. 52:81-116.
9. Earnest, D. L. 1997. Gastrointestinal system: introduction. In Comprehensive Toxicology, ed. R. S. McCuskey and D. L. Earnest, 505-506. New York: Elsevier Science.
10. Ernster, L. 1967. DT-Diaphorase. In Methods in Enzymology, ed. R. W. Estrabook and M. E. Pullman, 309-317. New York: Academic Press.
11. Fiske, C. H., and Subborow, Y. 1925. The colorimetric determination of phosphorus. J. Biol. Chem. 66:375-400.
12. Folch, J., Lees, M., and Sloane-Stanley, G. H. 1956. Isolation of total tissue lipids J. Biol. Chem. 226:497-509.
13. Forstner, G. G., Sabesin, S. M., and Isselbacher, K. J. 1968. Rat intestinal microvillus membrane. Biochem. J. 106:381-390.
14. Gabre-ab, T., Gabriel, W. Z., Maffi, M., Ahmed, M. M., Ayele, Z. T., and Fanta, H. 1978. Neurolathyrism: a review and report of an epidemic. Ethiopia Med. J. 16:1-11.
15. Gottschalk, A. 1960. Correlation between composition structure, shape and function of a salivary mucoprotein. Nature 186:949-951.
16. Habig, W. H., Pabst, M. J., and Jakoby, W. B. 1974. Glutathione-s-transferase: the first step in mercapturic acid formation. J. Biol. Chem. 249:7130-7139.
17. 2+ ATPase of transverse tubule membranes isolated from rabbit skeletal muscle. J. Biol. Chem. 256:13937-13945.
18. ITRC. 1975. Outbreak of paralysis in some villages of Unnao district of Uttar Pradesh: a preliminary epidemiological study. Industrial Toxicology Research Centre, Lucknow, India.
19. Jacobson, E. D. 1997. Gastrointestinal system: overview of physiology. In Comprehensive Toxicology, ed. I. G. Sipes, C. A. Mc Queen, and A. J. Gandolfi, 520-538. New York: Pergamon Press.
20. Jahan, K., and Ahmed, K. 1993. Studies on neurolathyrism. Environ. Res. 60:259-266.
21. Kaminsky, L. S., and Fasco, M. J. 1992. Small intestinal cytochrome P-450. CRC Crit Rev. Toxicol. 21:407-422.
22. Lebouton, A. V. 1997. Anatomy (Esophagus, Stomach, Small Intestine, Colon). In Comprehensive Toxicology, ed. R. S. McCuskey and D. L. Earnest, 507-518. New York: Elsevier Science.
23. Lowry, O. H., Rosenbrough, N. J., Farr, A. L., and Randall, R. J. 1951. Protein measurement by folin phenol reagent. J. Biol. Chem. 193:265-275.
24. Mishra, G. 1999. Chemico-toxicological studies on Lathyrus sativus: Effect of co-exposure of manganese. (PhD diss, Lucknow University).
25. Mukherjee, S., Upreti, R. K., Tekwani, B. L., and Kidwai A. M. 1992. Biochemical analysis of jejunal brush border membrane of golden hamster: pathogenic modulations due to ancylostomiasis. Indian J. Biochem. Biophys. 29:82-86.
26. Murakami, S., Yamada, H., Muramastu, M., Aihara, H., and Suwa, I. 1968. Effect of sofalcone on gastric mucous glycoprotein in experimental gastritis induced by sodium taurocholate. Res. Commun. Path. Pharm. 62:461-482.
27. Olney, J. W., Misra, C. H., and Rhee, V. 1976, Brain and retinal damage from lathyrus excitotoxin, β-N-oxalyl-L-α,β-diaminopriopionic acid. Nature 264:659-661.
28. Oser, B. L., and Oser, M. 1956. Nutrition studies on diet containing high levels of partial ester emulsifiers. J. Nutr. 60:367-390.
29. Porter, C. W., Dworacyzk, K., and Gurtoo, H. L. 1982. Biochemical localisation of aryl hydrocarbon hydroxylase in the intestinal epithelium of the rat. Cancer Res. 42:1283-1285.
30. Rao, S. L. N., Adiga, P. R., and Sarma, P. S. 1964. The isolation and characterization of β-N-oxalyl-L-β-diaminopropionic acid: a neurotoxin from the seeds of Lathyrus sativus. Biochemistry 3:432-436.
31. Rao, S. N. L., Sarma, P. S., Mani, K. S., Rao, T. R. R., and Srimachari, S. 1967. Experimental neurolathyrism in monkeys. Nature 214:610-611.
32. Roe, J. H. 1955. The determination of sugar in blood and fluid with anthrone reagent. J. Biol. Chem. 212:335-343.
33. Sadasivan, T. S., Sulochana, C. B., John, V. T., Subbaram, M. R., and Gopalan, C. 1960. Manganese and lathyrism. Curr. Sci. 29:86-87.
34. Schinitzky, M., and Inbar, M. 1974. Lipid structrual order parameter in biomembranes derived from steady-state fluorescence polarisation measurements. J. Mol. Biol. 85:603-615.
35. Schwank, M., and Locher, M. 1985. 1-Napthol conjugation in isolated cells from liver, jejunum, colon and kidney of the guinea pig. Biochem. Pharmacol. 34:697-701.
36. Seth, K., Mishra, G., Das, M., Agarwal, A. K., Khanna, S. K., and Seth, P. K. 2003. Effect of lathyrus and manganese and their co-exposure on neuroreceptors, intracellular calcium levels and membrane fludity in guinea pigs (Personal communication).
37. Snecdecor, G. W., and Cochran, W. G. 1967. One-way classification: analysis of variance. Statistical Methods, 6th ed., 258-296. Ames, IA: Iowa State University Press.
38. Vainio, H., and Hietanen, E. 1980 Role of extrahepatic metabolism. In Concepts in Drug Metabolism, ed. P. Jenner and B. Testa, 251-258. New York: Marcel Dekker.
39. Van Bliterswijk, V. W. J., Hoeven, V. R. P., and Meer, V. B. W. 1981. Biochem. Biophys. Acta 644:323-332.
40. Wagner, A., Lissau, A., Holzl, J., and Harhammer, L. 1962. The incorporation of p32 into the inositol phosphatides of rat brain. Lipid Res. 3:177-180.
41. Warren, L. 1959. The thiobarbituric acid assay of sialic acids. J. Biol. Chem. 234:1971-1975.
42. Watkins, J. B., and Klaassen, C. D. 1997. Absorption, enterohepatic circulation, and fecal excretion of toxicants. In Comprehensive Toxcology, vol. 9, ed. I. G. Sipes, C. A. McQueen, and A. I. Gandolfi, 626-637, New York: Pergamon Press.
43. Weiser, M. M. 1973. Intestinal epithelial cell surface membrane glycoprotein systhesis. L. an indication of cellular differentiation. J. Biol. Chem. 248:2536-2541.
44. Wills, C. L., Meldrum, B. S., Nunn, P. B., Anderton, B. H., and Leigh, P. N. 1993. Neuronal damage induced by 3-N-oxalylamino-L-alanine in the rat hippocampus can be prevented by a non-NMDA antagonist, 2,3-dihydroxy-6-nitro-7-sulfamoyl benzo(f)quinoxaline. Brain. Res. 627:55-62.
45. Zlatkis, A., Zak, B., and Vboyle, A. J. 1953. A new method for the direct determination of serum cholesterol. J. Lab. Clin. Med. 41:486-492.