Ligand-free palladium catalysed Heck reaction of methyl 2-acetamido acrylate and aryl bromides as key step in the synthesis of enantiopure substituted phenylalanines

Journal of Organometallic Chemistry

Volumn 687, Issue 2, 2003, Pages 494-497

  Willans, Charlotte E ^a   Mulders, Jan M C A ^a   de Vries, Johannes G ^a   de Vries, André H M ^a  

^a DSM Pharmaceutical Products   (Netherlands)

Author keywords

Heck; Ligand free; MonoPhos; Palladium; Substituted phenylalanines

Indexed keywords

ACETAMIDE DERIVATIVE; ACRYLIC ACID DERIVATIVE; BROMIDE; PALLADIUM; PHENYLALANINE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ENANTIOMER; ENANTIOSELECTIVITY; HECK REACTION; HYDROGENATION; SUBSTITUTION REACTION; SYNTHESIS;

EID: 0344012076     PISSN: 0022328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jorganchem.2003.09.012     Document Type: Article

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