Twenty-Eight Day Repeated Dose Oral Toxicity Test of Synergist of a pyrethroid insecticide, 2, 3, 3, 3, 2′, 3′, 3′, 3′-Octachlorodipropyl ether (S-421) in Rats

Bulletin of National Institute of Health Sciences

Volumn , Issue 121, 2003, Pages 40-47

  Matsushima, Yuko ^a   Uchida, Osayuki ^b   Saitoh, Minoru ^b   Kawasaki, Yasushi ^b   Isama, Kazuo ^b   Kaniwa, Masaaki ^b   Inoue, Tohru ^b   Kanno, Jun ^b  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b NONE

Author keywords

A twenty eight day repeated oral dose toxicity test; Hepatotoxicity; Insecticides; Pyrethroid; Rat; S 421

Indexed keywords

2,3,3,3,2',3',3',3' OCTACHLORODIPROPYL ETHER; ETHER DERIVATIVE; HEMOGLOBIN; INSECTICIDE; PYRETHROID; UNCLASSIFIED DRUG;

ACCIDENT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD CHEMISTRY; BODY WEIGHT; CELL SWELLING; CELL VACUOLE; CONTROLLED STUDY; DROWSINESS; EXPERIMENTAL TEST; HEMATOLOGY; INTERMETHOD COMPARISON; LEUKOCYTE; LIVER CELL; LIVER NECROSIS; LIVER WEIGHT; LONG TERM EXPOSURE; MEAN CORPUSCULAR HEMOGLOBIN; NONHUMAN; RAT; SEX DIFFERENCE; SURVIVAL RATE; TREATMENT OUTCOME;

ACUTE TOXICITY TESTS; ADMINISTRATION, ORAL; ANIMALS; BLOOD CELLS; BODY WEIGHT; ETHERS; FEMALE; HYPERTROPHY; INSECTICIDES; LIVER; MALE; NECROSIS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; RATS; RATS, WISTAR; TIME FACTORS;

EID: 0344010098     PISSN: 13434292     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Miyazaki, T., Residues of the synergist S-421 in human milk collected from the Tokyo metropolitan area. Bull Environ Contam Toxicol, 29(5), 566-569 (1982)
2. Miyazaki, T., Kaneko, S., Horii, S., Yamagishi, T., Identification of the synergist bi (2,3,3,3,-tetrachloropropyl) ether in human milk, Bull Environ Contam Toxicol, 26(3), 420-423 (1981)
3. Uno, M., Onji, Y., Sasaki, M., Tanigawa, K., Residual Pyrethroid Insecticides in the Interior of a House, EISEI KAGAKU, 30(4): 207-210 (1984)
4. Sekita, S., Kawasaki, Y., Matsumoto, S., Ochiai, T., Nakaji, Y., Kobayashi, K., Furuya, T., Kurokawa, Y., Tobe, M, Subacute Toxicity Study for Bis (2,3,3,3-tetrachloropropyl) ether, Bulletin of National Institute of Hygienic Sciences, 106, 33-38,(1988)
5. Takahashi, O., Oishi, S., Fujitani, T., Tanaka, T., Yoneyama, M., Chronic toxicity studies of piperonyl butoxide in F344 rats: induction of hepatocellular carcinoma. Fundam. Appl. Toxicol, 22, 293-303 (1994)
6. Hirose, C., Current trends and Topics of the Insecticide Market, Journal of Pesticides Science, 2, 187-200 (1977)