Overexpression of the ferritin iron-responsive element decreases the labile iron pool and abolishes the regulation of iron absorption by intestinal epithelial (Caco-2) cells

Journal of Biological Chemistry

Volumn 275, Issue 3, 2000, Pages 1651-1655

  Gárate, Marco A ^a   Núñez, Marco T ^a  

^a UNIVERSITY OF CHILE   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN; IRON REGULATORY FACTOR; MESSENGER RNA;

ARTICLE; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM; IRON ABSORPTION; IRON METABOLISM; IRON TRANSPORT; PRIORITY JOURNAL; RNA TRANSLATION;

CACO-2 CELLS; FERRITINS; FLUORESCEINS; FLUORESCENT DYES; HUMANS; IRON; KINETICS; RECEPTORS, TRANSFERRIN; RNA, MESSENGER; RNA-BINDING PROTEINS; SPECTROMETRY, FLUORESCENCE; TIME FACTORS; TRANSFECTION;

MAMMALIA;

EID: 0343986454     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.3.1651     Document Type: Article

References (31)

1. Flanagan, P. R. (1990) Acta Pediatr. Scan. Suppl. 361, 21-30
2. Gavin, M. W., McCarthy, D. M., and Garry, P. J. (1994) Am. J. Clin. Nutr. 59, 1376-1380
3. Tapia, V., Arredondo, M., and Núñez, M. T. (1996) Am. J. Physiol. 271, G443-G447
4. Alvarez-Hernandez, X., Smith, M., and Glass, J. (1994) Biochim. Biophys. Acta 1192, 215-222
5. Hillgreen, K. M., Kato, A., and Borchardt, R. T. (1995) Med. Res. Rev. 15, 83-109
6. Núñez, M. T., Tapia, V., and Arredondo, M. (1996) J. Nutr. 126, 2151-2158
7. Núñez, M. T., Alvarez, X., Smith, M., Tapia, V., and Glass, J. (1994) Am. J. Physiol. 267, C1582-C1588
8. Han, O., Failla, M. L., Hill, D., Morris, E. R., and Smith, J. C. (1995) J. Nutr. 125, 1291-1299
9. Leibold, E. A., and Munro, H. N. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 2171-2175
10. Mullner, E. W., Neupert, B., and Kühn, L. C. (1989) Cell 58, 373-382
11. Klausner, R. D., Rouault, T. A., and Hartford, J. B. (1993) Cell 72, 19-28
12. Samaniego, F., Chin, J., Iwai, K., Rouault, T. A., and Klausner, R. D. (1994) J. Biol. Chem. 269, 30904-30910
13. Guo, B., Yu, Y., and Leibold, E. A. (1994) J. Biol. Chem. 269, 24252-24260
14. Iwai, K., Klausner, R. D., and Rouault, T. A. (1995) EMBO J. 14, 5350-5357
15. Kim, H.-Y., Klausner, R. D., and Rouault, T. A. (1995) J. Biol. Chem. 270, 4983-4986
16. Iwai, K., Drake, S. K., Wehr, N. B., Weissman, A. M., LaVaute, T., Minato, N., Klausner, R. L., Levine, R. L., and Rouault, T. J. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 4924-4928
17. Kennedy, M. C., Emptage, M. C., Dreyer, J.-L., and Beinert, H. (1983) J. Biol. Chem. 258, 11098-11105
18. DeRusso, P. A., Philpott, C. C., Iwai, K., Mostowski, H. S., Klausner, R. D., and Rouault, T. (1995) J. Biol. Chem. 270, 15451-15454
19. Arredondo, M., Orellana, A., Gárate, M. A., and Núñez, M. T. (1997) Am. J. Physiol. 273, G275-G280
20. Flanagan, P. R., Hadju, A., and Adams, P. C. (1995) Hepatology 22, 828-832
21. Pietrangelo, A., Rocchi, E., Casalgrandi, G., Rigo, G., Ferrari, A., Perini, M., Ventura, G., and Cairo, G. (1992) Gastroenterology 120, 802-809
22. Gaetano Cairo, G., Recalcati, S., Montosi, G., Castrusini, E., Conte, D., and Pietrangelo, A. (1997) Blood 89, 2546-2553
23. Ausubel, F., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Shmith, J. A., and Struhl, K. (1995) Short Protocols in Molecular Biology, 3rd. Ed., pp. 4.22-4.25, John Wiley and Sons, New York
24. Harlow, E., and Lane, D. (1988) Antibodies: A Laboratory Manual, pp. 553-612, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
25. Epsztejn, S., Kakhlon, O., Glickstein, H., Breuer, W., and Cabantchik, Z. I. (1997) Anal. Biochem. 248, 31-40
26. Boyd, D., Vecoli, C., Belcher, D. M., Jain, S. K., and Drysdale, J. W. (1985) J. Biol. Chem. 260, 11755-11761
27. Gunshin, H., Mackenzie, B., Berger, U. V., Gunshin, Y., Romero, M. F., Boron, W. F., Nussberger, S., Gollan, J. L., and Hediger M. A. (1997) Nature 388, 482-488
28. Fleming, M. D., Trenor, C. C., III, Su, M. A., Foerntzler, D., Beier, D. R., Dietrich, W. F., and Andrews, N. C. (1997) Nat. Genet. 16, 383-386
29. Gutiérrez, J. A., Yu, J., Rivera, S., and Wessling-Resnick, M. (1997) J. Cell Biol. 139, 895-905
30. Lee, P. L., Gelbart, T., West, C., Halloran, C., and Beutler, E. (1998) Blood Cells Mol. Dis. 24, 199-215
31. Topham, R. W., Eads, C. E., and Butler, B. F. (1992) Biochem. J. 284, 877-884